1,721,026 research outputs found
Oli essenziali nel trattamento delle dermatiti parassitarie da artropodi e da micetri degli animali domestici
No full textIn vitro anthelmintic activity of plant-derived active principles against sheep gastrointestinal nematodes
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Efficacy of mangiferin against Cryptosporidium parvum in a neonatal mouse model.
No full textThe inhibitory activity of mangiferin (50 mg/kg/die and 100 mg/kg/die) on Cryptosporidium parvum was evaluated in a neonatal mouse model and its activity was compared with that of paromomycin (100 mg/kg/die). At 4 days of age, neonatal Swiss conventional outbred mice were experimentally infected by oral administration of 10(4) oocysts/animal of C. parvum and treated orally for 10 consecutive days, starting 7 days after the experimental infection. One group of mice was left untreated. To evaluate the efficacy of mangiferin, from euthanised mice, 3-mu m-thick tissue sections of the intestine were stained with haematoxylin-eosin and periodic acid Schiff. Immunohistochemistry was also used by employing a monoclonal anti-C. parvum antibody. Oocysts were counted and results were expressed as mean oocysts number/intestine. Results obtained show that mangiferin at 100 mg/kg/die has a significant anticryptosporidial activity and that its activity is similar to that showed by the same dose (100 mg/kg/die) of paromomycin. However, both mangiferin and paromomycin were not able to completely inhibit intestinal colonization of C. parvum but only to reduce it. This reduction was calculated at over 80% for both mangiferin and paromomycin with respect to the untreated control. A significant activity was found also for mangiferin at 50 mg/kg/die only after the end of treatment
Oocyst excretion pattern of three intestinal Eimeria species in female rabbits.
Full text linkAbstract: The dynamic change in faecal Eimeria oocyst excretion was evaluated in 10 naturally infected
female rabbits, starting from their weaning at 33 d of age until about 1 mo after their second parturition.
Faecal samples collected from examined animals were quali-quantitatively analysed to evaluate presence
and number of Eimeria oocysts. In addition, isolated Eimeria oocysts were identified at the species level
following sporulation. Animals were found to be infected by Eimeria perforans, Eimeria exigua and Eimeria
magna and shed Eimeria oocysts after weaning and after parturition. In particular, at 33 d of age all female
rabbits examined were negative, while the discharge of Eimeria oocysts started at 39th day of age and peaked
between 46th and 53rd day of age. From 81-109 d of age until the first parturition and from 25 d of age of
the litters born at the first parturition to the second parturition, all animals resulted negative. After parturition,
Eimeria oocyst output occurred from 6th to 12th day after the first parturition and from 7th to 13th day after the
second parturition, while a second period of oocyst excretion was observed from 18th to 24th day after both
parturitions. These findings may indicate the existence of a relationship between the periparturient phase
and Eimeria oocyst output and suggest an important role of the mothers in transmission of the infection to
their litter
Efficacy of an Aqueous Extract of Stellaria media (L.) Cyr. against Eimeria legionensis Infection (Apicomplexa: Eimeridae) in Red-legged Partridges (Alectoris rufa)
Full text linkAims: Coccidiosis is one of the most frequent causes of morbidity and mortality in farmed redlegged partridges (Alectoris rufa). The aim of this study was to evaluate the effects of the plant Stellaria media (Caryophyllaceae) on coccidia-infected red-legged partridges.
Methodology: Of 9 replicates of redlegged partridges, each composed by 6 coccidia-infected birds (Eimeria legionensis), 3 replicates (S group) received an aqueous extract (12 ml/l) of S. media with drinking water for 3 consecutive days, while 3 further replicates (D group) received 20% sodium sulfaquinoxaline (2 g/l) with drinking water for 3 consecutive days. The remaining 3 replicates did not receive any treatment (C group). The day before the beginning of the treatment (day 0), the last day of the treatment (day 3) and 7 days after the end of the treatment (day 10), individual fresh faecal samples were collected from all examined birds and analysed for presence and number of coccidian oocysts/gram of faeces (OPG). Data were statistically elaborated with the Analysis of Variance (ANOVA) and the Test of Student-Newman-Keuls for multiple comparisons. The percentage of reduction of the mean OPG number was also assessed. In addition, all birds were clinically observed in order to evaluate the appearance of diarrhoea and of other signs of clinical coccidiosis.
Results: Seven days after the end of the treatment, birds of the C group showed diarrhoea and significant (P<0.05) higher OPG numbers respect to those of S and D groups, while no significant differences resulted between S and D groups. Moreover, percentages of OPG reduction of 98.61% and 99.60% and of 99.23% and 78.46% were found at day 3 and day 10 for group S and group D, respectively, while an increased mean OPG number was observed in the untreated group (C).
Conclusion: After oral administration to the examined red-legged partridges S. media was able not only to prevent the clinical form of coccidiosis, but also to give a significant reduction of E. legionensis OPG number in faecal samples of birds treated with this plant. This reduction resulted comparable to that observed in animals treated with the commercial drug
Efficacia Acaricida di un olio essenziale di cannella nei confronti di Psoroptes cuniculi
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