1,721,044 research outputs found
The Formation of 2-Hydroxy-but-3-enyl Cyanide from (2S)-Hydroxybut-3-enyl Glucosinolate using Immobilized Myrosinase
No full text
N-(2-Phenylprop-1-enyl) proline methylester : equilibrium between the enamine and the aza methine ylide form.
No full textCarbo- and Heterocyclization Reactions of 2-(4-Morpholinyl)-1-phenylpropene and Nitroolefins
No full textA facile chemoenzymatic approach to chiral non-racemic beta-alkyl-gamma-amino acids and 2-alkylsuccinic acids.A concise synthesis of (S)-(+)-Pregabalin
No full textBoth enantiomerically pure antipodes of GABA analogues were prepared as hydrochloride salts, by enzymatic kinetic resolution of their precursors ethyl 2-(nitromethyl)alkanoates. These latter compounds can be easily transformed into enantiomerically pure 2-alkylsuccinic acids by a Nef reaction followed by oxidation. Interestingly, this reaction was particularly easy for the neopentyl derivative (S)-(+)-7d, which underwent conversion into its corresponding succinic acid derivative (S)-()-8d in buffered solution. The absolute configurations of the main compounds of interest involved are given, together with their CD spectr
A Facile Route To Polysubstituted 2-Hydroxy-3-nitrocyclopentanones via a Linear alpha-Ketoenamine
No full textNitroalkylation Reactions of Methyl 2-(4-Morpholinyl)acrylate. Synthesis of alpha,omega-Dioxoesters
No full textA Facile Route To (+)- and (–)-trans-Tetrahydro-5-oxo-2-pentylfuran-3-carboxylic Acid, Precursors of (+)- and (–)-Methylenolactocin
No full textThe enantioselective synthesis of the title compound is easily achieved by enzymatic kinetic resolution of the parent racemic carboxylic ester
Cyclopentaannulation Reactions between Nitrocycloalkenes and Diacetyl Morpholino Enamine
No full textSynthesis of Polysubstituted Pyrrolizidines from Proline Derivatives and Conjugated Nitroolefins
No full text- …
