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Mosquito symbionts as a tool for mosquito borne disease control.
No full textMosquito symbionts as a tool for mosquito borne disease control
Plenary Session intitolata "genetic modification of mosquitoes and symbionts " all'interno del workshop "Reducing Plasmodium transmission and malaria burden by integrated vector control"
No full textTo gain knowledge on novel vector control tools based on genetic modification of mosquitoes or bacteria associated to the vector: i) various technical approaches pursued, strengths and weaknesses in view of a possible future implementation ii) ethical, legal and social issues related to implementing vector control based on genetically modified mosquitoes/symbiotic organisms
Engineered mosquitoes to fight mosquito borne diseases: not a merely technical issue
Full text linkMalaria, dengue and other mosquito-borne diseases pose dramatic problems of public health, particularly in tropical and sub-tropical countries. Historically, vector control has been one of the most successfully strategies to eradicate some mosquito-borne diseases, as witnessed by malaria eradication in Mediterranean regions such as Italy and Greece. Vector control through insecticides has been used worldwide; unfortunately, it is losing effectiveness due to spread of resistances. Control of mosquito-borne diseases through field-releases of genetically engineered mosquitoes is an innovative and now feasible approach. Genetically modified mosquitoes have already been released into the wild in some regions, and protocols for this release are on hand in others. Local authorities are vigilant that transgenic insects in the field are safe for human and animal populations, and the public engagement in every control program is assuming a central role
Symbionts conferring resistance to viruses in insects
No full textRecently, PLoS Pathogens published an interesting
paper of Julien Martinez and collaborators, about the
protective role of Wolbachia from viral infections in
Drosophila hosts.
This work is part of a wider context of studies aimed
to define the mechanisms of Wolbachia-mediated
protection to a broad spectrum of pathogens in insects
infected with specific strains of this bacterium. The
exploitation of bacterial symbionts represents a very
hot topic in regard to the control of diseases
transmitted by insect vectors. In fact, recently the
Wolbachia infection of mosquito vectors of Dengue
virus turned out to be an innovative approach,
particularly effective in combating this infection
Mosquito symbionts: perspectives in diseases control.
No full textIt is well accepted that the symbiotic relationships insects have established with several
microorganisms have had a key role in their evolutionary success. Bacterial symbiosis is also prevalent
in insect vectors, and numerous studies have sought to decrypt the basic mechanisms of the host–
symbiont relationships and develop ways to control vector borne diseases. ‘Symbiotic control’ that uses
symbiotic microorganisms to control insect pests or reduce vector competence, seems particularly
promising. Three such approaches currently at the cutting edge are: i) the disruption of microbial
symbionts required by insect pests; ii) the manipulation of symbionts that can express anti-pathogen
molecules within the host; and iii) the introduction of endogenous microbes that affect life-span and
vector capacity of the new hosts in insect populations.
I will present new advancement in the field of mosquito symbiosis with particular regards to the
interactions between mosquitoes and bacteria of the genus Asaia
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