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Template for assessing bone quality and methods of use thereof
No full textUnited States Patent Application 20080119719
Kind Code A1
Ascenzi; Maria-Grazia ; et al. May 22, 2008
TEMPLATES FOR ASSESSING BONE QUALITY AND METHODS OF USE THEREOF
Abstract
The present invention relates to the preparation and use of novel bone templates that can be prepared using a
comprehensive approach to observing microstructural features of bone, including trabecular thickness and
trabecular density. These features are assessed in regions of interest in a bone (e.g., proximal femur, distal
femur, wrist, spine, etc.) as observed using digital radiographic techniques or clinical imaging, such as Dual
Energy X-ray Absorptiometry (DEXA) and computed tomography (CT) scanners. The microstructural
features are presented in the form of data based on scanning results and are also assessed and/or organized in
terms of age, gender, race, pathology, clinical history, and other patient population parameters. The template
can be used to assess bone quality, predict the likelihood of bone fracture, and evaluate prosthesis design and
placement, based on an image of a corresponding subject bone, e.g. the bone of a patient.
Inventors: Ascenzi; Maria-Grazia; (Santa Monica, CA) ; Favia; Angela; (Bari, IT)
Assignee: The Regents of the University of California
Oakland
CA
Class at Publication: 600/410; 435/4
International Class: C12Q 1/00 20060101 C12Q001/00; A61B 5/05 20060101
A61B005/0
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