125 research outputs found

    Supplementary_Data – Supplemental material for Are we there yet with patent foramen ovale closure for secondary prevention in cryptogenic stroke? A systematic review and meta-analysis of randomized trials

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    Supplemental material, Supplementary_Data for Are we there yet with patent foramen ovale closure for secondary prevention in cryptogenic stroke? A systematic review and meta-analysis of randomized trials by Pradyumna Agasthi, Kantha Ratnam Kolla, Charan Yerasi, Sibghat Tullah, Venkata Siva Pulivarthi, Boshra Louka, Reza Arsanjani, Eric H Yang, Farouk Mookadam and F David Fortuin in SAGE Open Medicine</p

    Perioperative venous thromboembolic disease and the emerging role of the novel oral anticoagulants: An analysis of the implications for perioperative management

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    Venous thromboembolism includes 2 inter-related conditions: Deep venous thrombosis and pulmonary embolism. Heparin and low-molecular-weight heparin followed by oral anticoagulation with vitamin K agonists is the first line and current accepted standard therapy with good efficacy. However, this therapeutic strategy has many limitations including the significant risk of bleeding and drug, food and disease interactions that require frequent monitoring. Dabigatran, rivaroxaban, apixaban, and edoxaban are the novel oral anticoagulants that are available for use in stroke prevention in atrial fibrillation and for the treatment and prevention of venous thromboembolism (HYPERLINK\l "1). Recent prospective randomized trials comparing the NOACs with warfarin have shown similar efficacy between the treatment strategies but fewer bleeding episodes with the NOACs. This paper presents an evidence-based review describing the efficacy and safety of the new anticoagulants compared to warfarin

    Back to the future: of fevers and failures

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    Unicuspid Aortic Valve

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    A case of hemolysis after percutaneous ventricular septal defect closure with a device.

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    Hemolytic anemia related to intracardiac prosthetic materials has been described. We describe a case of a 74-year-old female with a history of hypertrophic obstructive cardiomyopathy that had a postoperative ventricular septal defect closed with a muscular ventricular septal defect occluder. The device caused intractable hemolytic anemia that required surgical removal and repair. We describe a rare cause of hemolysis complicating transcatheter closure of a post-traumatic ventricular septal defect

    Body Composition and Wages

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    This paper examines the effect of body composition on wages. We develop measures of body composition – body fat (BF) and fat-free mass (FFM) – using data on bioelectrical impedance analysis (BIA) that are available in the National Health and Nutrition Examination Survey III and estimate wage models for white respondents in the National Longitudinal Survey of Youth 1979. Previous research used body size or BMI for measuring obesity despite the growing concern in the medical literature that BMI-based measures do not distinguish between body fat and fat-free body mass and that BMI does not adequately control for non-homogeneity inside human body. Therefore, measures used in this paper represent a useful alternative to BMI-based proxies of obesity. This paper also contributes to the growing literature on the role of non-cognitive skills on wage determination. Our results indicate that calculated BF is unambiguously associated with decreased wages for both males and females among whites We also present evidence indicating that FFM is consistently associated with increased wages. We show that these results are not the artifacts of unobserved heterogeneity. Finally, our findings are robust to numerous specification checks and to a large number of alternative BIA prediction equations from which the body composition measures are derived.
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