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Presence of atrial natriuretic factor (ANF) in the carcinoma of human breast. Ital. J. Anat. Embryol.
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Presence of atrial natriuretic factor in normal and hyperplastic human prostate and its relationship with oxytocin localisation
Full text linkIn this work, we showed the presence of atrial natriuretic factor (ANF) in human prostate and compared its localisation in normal and hyperplastic conditions. ANF was localised in epithelial and stromal cells, being increased in hyperplasia, mainly in the stromal component. Moreover, we compared ANF and oxytocin positivity in the same glands, focusing on the possible relationship between the paracrine effects of these two hormones
Utrastructural biologic effects of sonography with pulse inversion and microbubble contrast in rabbit liver
No full textPURPOSE:This prospective study was conducted to evaluate the biologic effects of microbubble destruction with pulse-inversion harmonic imaging on rabbit liver parenchyma.
METHODS:The livers of 6 albino rabbits were examined sonographically by a single investigator. Three rabbits underwent contrast-enhanced sonography, with scanning starting 5 seconds after injection by using pulse-inversion harmonic imaging with a mechanical index of 1.2. Four time-triggered images were recorded at a rate of 1 frame every 2 seconds. For comparison, 3 control rabbits had pulse-inversion harmonic imaging with a mechanical index of 1.2 only, without contrast medium. Immediately after sonography, the animals were killed and uninterrupted, thin serial sections of the liver from both groups were analyzed by energy-filtered transmission electron microscopy.
RESULTS:The hepatic parenchyma of rabbits exposed to contrast agents had ultrastructural damage: mitochondria with fragmented crests; interrupted rough endoplasmic reticulum; enlarged intercellular spaces; highly vacuolized cytoplasmic areas; dilated sinusoids, sometimes with an irregular and interrupted endothelial wall; fragmented hepatocyte microvilli in dilated spaces of Disse; fragmented or missing microvilli in bile canaliculi; vacuolated and lysosome-deprived hepatic cytoplasm around the bile canaliculi; markedly injured or fragmented endothelium in larger vessels; and damaged basal membrane. Control-group results indicated that exposure to ultrasound alone did not cause ultrastructural damage to hepatic cells.CONCLUSIONS:Simultaneous exposure to contrast administration and pulse-inversion harmonic imaging with a high mechanical index causes ultrastructural damage in the rabbit liver
ABDOMINAL AORTIC ANEURYSM WALL RUPTURE RISK EVALUATION THROUGH COMPUTERIZED FINITE ELEMENT ANALYSIS MODEL AND FUZZY-TOPSIS DECISION METHOD
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Histochemical Geography and Ultrastructural Remarks of the Urinary Tract in Some Mammals
No full textOur investigations oriented towards the urinary tracts, particulary the bladder and ureter, were carried out by histochemical and ultrastructural studies by SEM and TEM observation. In this segment of urinary tract, by structural, ultrastructural and chemical analysis, have evinced variations related to different animal species (guinea pig, rabbit and rat). The bladder wall was considered from us for histochemical aspects related to hydrolytic lysosomial enzymes (Ac-Phase; Na-beta-Gase) and oxidative enzymes (SDH; Iso-DH; MADH) and ultrastructural aspect with TEM. The SEM observations showed the connection between morphovolumetric variations of uroepithelial cells and respiratory enzymatic activity
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