1,721,268 research outputs found
How can we help patients with major depressive disorder (MDD) and schizophrenia to gain the most benefit from their treatment?
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Overcoming hurdles to achieving good physical health in patients treated with atypical antipsychotics
No full textHurdles that must be overcome in order to implement guidelines and maximize physical health in patients treated with antipsychotics include the impression that a disruption in physical health is an inevitable token for the patient to pay in order to achieve and maintain his or her mental health; lack of routine monitoring; lack of defined care pathways for evaluation, monitoring and treatment of physical health issues in psychiatry; the burden of guideline implementation on mental health team resources; the difficulty to perform certain procedures (e.g. monitoring of waist circumference); and reluctance to switch medications once physical health effects are recognized, especially if the psychiatric symptoms are under relatively good control. It is imperative that we act now to overcome these hurdles and maximize outcomes for our patients. Strategies include establishing simple, consistent processes for physical health monitoring and tracking in clinical practice; provision of appropriate equipment to staff; effective education of all personnel involved in the care of psychiatric patients regarding this important topic; and consideration of a medication switch in patients whose medication is a high-risk contributory factor to poor physical health. © 2008 Elsevier B.V. and ECNP
From study to practice in bipolar mania: Recommendations for optimizing the clinical benefits of new antipsychotics
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The art and science of switching in patients with schizophrenia: Strategies for achieving a smooth transition
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Perfenazina, amitriptilina e perfenazina-amitriptilina: Ruolo nella pratica clinica [Perphenazine, amitriptyline and perphenazine-amitriptyline: Role in clinical practice]
Full text linkTypical antipsychotics, also called conventional antipsychotics, first-generation antipsychotics or major tranquilizers, and tricyclic antidepressants, are drugs developed since 1950 and still used in the treatment of many psychiatric disorders, despite several compounds that were developed later, with the intention of improving their therapeutic response and tolerability. Although the efficacy, tolerability, value and usefulness of the new compounds are undeniable, none of these is so effective and tolerated to make us consider the older generation drugs as always and completely overtaken. This paper evaluates and reviews the pharmacological and clinical properties of perphenazine, amitriptyline and the association of these two medications
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