625 research outputs found

    Epithelial abnormalities in cystic ovarian endometriosis

    No full text
    Objective. To evaluate the prevalence of epithelial abnormalities in cystic ovarian endometriosis. Methods. In this observational study, the specimens of 388 consecutive patients undergoing a surgical procedure whose final diagnosis included cystic ovarian endometriosis were histopathologically reviewed. The prevalence and patient characteristics of cases featuring epithelial metaplasia, hyperplasia, atypia, and endometrioid carcinoma arising in endometriosis were analyzed. Results. The epithelial lining was evaluable in 339 cases. Left-sided cysts were significantly more common than right-sided ones (P < 0.0001). The observed prevalence was 12.1% for metaplasia, 9.4% for hyperplasia, 5.9% for atypia, and 4.1% for endometrioid carcinoma arising in endometriosis. Complex hyperplasia, but not simple hyperplasia or metaplasia, was significantly more common in cases with associated endometrioid carcinoma than in all other cases (P < 0.00001). A statistically significant trend for increasing age from normal epithelium to carcinoma was observed (P < 0.001). Conclusions. Epithelial abnormalities are a common finding in cystic ovarian endometriosis. Despite their clinical significance being still debated, complex hyperplasia and atypia can be associated with malignant transformation of endometriosis. Their observation in a surgical specimen, particularly in older patients, should indicate a careful examination of the entire lining of the cyst and a strict follow-up of the patient

    The effects of water management on annual maximum floods of Lake Como and River Adda at Lecco (Italy)

    No full text
    This paper presents the results of an analysis aimed to assess the impact exerted on the flood regime of Lake Como and its emissary by different kinds of waterworks in the Adda basin (Italy). This includes construction of reservoirs in the Alps, increase in flow capacity of the exutory and regulation of Lake Como. The assessment of the management effect on peak floods is of particular interest as flood damages could be particularly heavy in densely populated areas along the lake banks and in the river flood plain downstream of the lake. The analysis is carried out by comparing the annual maxima of Lake Como levels and the river Adda discharges at Lecco, at the lake exutory, in different real and hypothetical situations. Both the construction of alpine reservoirs and the improvement of flow capacity of the exutory decrease lake levels and flood discharges, while lake regulation (for irrigation and power production) increases them. The overall effect is a generalised reduction of the flood levels and a slight increase in the discharges with return periods lower than 10 years. The discharges with higher return periods, instead, remain unchanged. The difference between peak and mean daily discharges negligible in all cases disappears altogether for return periods higher than 10 years

    Usury in Christian Middle Ages. A Reconsideration of the Historiographical Tradition (1949-2010)

    No full text
    The widespread historiographical idea that usury and its forbidding were the heart of the medieval economic doctrine, and at the same time the idea that something like a coherent medieval economic doctrine had existed, are however two very typical interconnected and complementary historical assumptions widely represented by European economic historians since the beginning of the past century, and firmly recapitulated in the Fifties and Sixties by historians devoted to explain, on the whole, the transition from feudal to capitalistic mode of production, are criticized and the entire problem is reshaped

    "E' più facile per un cammello": il denaro, le sue raffigurazioni, il suo uso e la produzione artistica tra XIII e XV secolo

    No full text
    Il contributo passa in rassegna le differenti tipologie della raffigurazione del denaro nell'arte medievale; il valore riproduttivo 'neutro', quello morale (specie nella raffigurazioni allegoriche di certe figure chiave, come Giuda), quello di suggestione antichizzante. Considera inoltre l'uso di non raffigurarlo, come una sorta di 'disagio della ricchezza'
    corecore