912 research outputs found

    Erasmo in Italia: la traduzione dell’Institutio principis christiani curata da Francesco Angelo Coccio (1539).

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    La centralità del ruolo di Erasmo da Rotterdam nella letteratura politica rinascimentale italiana – oltre che europea – è dato ormai da tempo acquisito. L’Institutio principis christiani, il trattato che l’umanista olandese dedicò, nel 1516, al futuro Carlo V, in particolare, rivela numerosi punti di contatto con le matrici culturali, platoniche e aristoteliche, del pensiero politico dell’Umanesimo italiano. Nel 1538 venne pubblicata a Venezia, per i tipi di Francesco Marcolini, la prima traduzione italiana dell’Institutio erasmiana, curata da Francesco Angelo Coccio, umanista e traduttore originario di Arezzo, e dedicata a Ferrante Francesco d’Avalos, marchese di Pescara. Il presente contributo si propone due obiettivi: anzitutto, contestualizzare l’operazione messa in atto da Coccio – non ‘neutra’, ovviamente, come tutte le traduzioni – e comprendere in qual modo e entro quali limiti essa rappresenti un capitolo della fortuna italiana di Erasmo; in secondo luogo, indagare le caratteristiche della concreta prassi versoria di Coccio al fine di lumeggiare le modalità del riuso di nozioni politiche della tradizione

    Risk of long-term pelvic recurrences after fluid minihysteroscopy in women with endometrial carcinoma: a controlled randomized study

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    Menopause. 2010 May-Jun;17(3):511-5. Risk of long-term pelvic recurrences after fluid minihysteroscopy in women with endometrial carcinoma: a controlled randomized study. Cicinelli E, Tinelli R, Colafiglio G, Fortunato F, Fusco A, Mastrolia S, Fucci AR, Lepera A. Source Department of Obstetrics and Gynecology, University Medical School of Bari, 70124 Bari, Italy. [email protected] Abstract OBJECTIVE: Concerns exist about the risk of endometrial cancer cells spreading into the peritoneal cavity after fluid minihysteroscopy. The aim of our study was to evaluate the 5-year incidence of pelvic recurrences in women affected by early-stage endometrial carcinoma (stage IA or IB) who did or did not undergo preoperative hysteroscopy with low pressure (<70 mm Hg) saline uterine distention. METHODS: A total of 140 women were randomized into two groups of 70 women who underwent or did not undergo diagnostic fluid minihysteroscopy before surgical staging. Women were followed up every 6 months for at least 5 years. Diagnosis of pelvic recurrence was based on a positive result at clinical examination and/or at vaginal cytology and/or at magnetic resonance imaging/positron emission tomography scan. Univariate analysis of disease-free survival was performed with the Kaplan-Meier method and survival curves were compared using the long-rank test. RESULTS: No difference in peritoneal cytology was observed between the two groups (5.7% and 8.5% of cases in the hysteroscopy and control group, respectively). After a mean duration of follow-up of 62 months, 2 (2.85%) pelvic recurrences in the hysteroscopy group and 3 (4.28%) in the control group were found. No significant difference was found between the two groups when the recurrence rate was compared. Overall survival rates and disease-free survival projected by Kaplan-Meier curves were not significantly different for the two groups. CONCLUSIONS: Preoperative low-pressure fluid minihysteroscopy does not increase the risk of intraperitoneal transport of endometrial carcinoma cells during the examination or the risk of pelvic recurrence at the 5-year follow-up. It does not seem to modify the recurrence rate, disease-free survival, and overall survival, although multicenter randomized trials and long-term follow-up are required to evaluate the overall oncologic outcomes of this procedure. PMID:2008 1548 [PubMed - indexed for MEDLINE

    Feasibility, safety, and efficacy of conservative laparoscopic treatment of borderline ovarian tumors.

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    OBJECTIVE: To outline the most recent information regarding conservative laparoscopic surgery for young women with borderline ovarian tumors. DESIGN: Review article. SETTING: Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy. PATIENT(S): Young women with low-stage borderline ovarian tumors who wish to preserve their fertility. INTERVENTION(S): Conservative laparoscopic surgery with unilateral salpingo-oophorectomy or cystectomy. MAIN OUTCOME MEASURE(S): Recurrence rate and outcomes. RESULT(S): Laparoscopic cystectomy may have more chance of preserving a woman's fertility compared with adnexectomy because of the removal of less ovarian tissue. Its greatest danger is the risk of inadvertently leaving behind some malignant cells. Therefore, this procedure should be reserved for patients with previous unilateral salpingo-oophorectomy or when bilateral lesions are present to preserve at least some ovarian tissue. CONCLUSION(S): When borderline ovarian tumors are identified at surgery by intraoperative histology, the recommended conservative treatment should be laparoscopic salpingo-oophorectomy. Recurrence can be noted after this type of treatment, but the cases of recurrent disease can be detected with close follow-up and treated accordingly. For these reasons, careful selection of candidates for this kind of treatment is, of course, necessary and close follow-up is required. If these restrictions are rigorously applied, then fertility-sparing surgery may be considered a safe option for this pathology, but all laparoscopic procedures should be reserved for oncologic surgeons trained in extensive laparoscopic procedures

    Visual neglect: does it exist in children with unilateral brain lesion? A systematic review

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    Visual Neglect (VN) is a common neuropsychological disorder in adults with unilateral brain lesion (UBL), characterized by the failure to attend and to report sensory events occurring in one side of space, contralateral to an area of brain damage. Less is known about VN expression in children following brain injury. The aim of this systematic review is to evaluate the presence of VN in UBL children and to identify the best neuropsychological assessment’s tool for this population. A comprehensive search of 4 databases (Pubmed, Cochrane Database, SCOPUS, DARE) was undertaken from May 2020 to January 2021. Inclusion criteria were (i) subjects less than 18 years with cerebral lesions and with MRI, (ii) specific neuropsychological assessments for VN, (iii) studies published in English since 2000. A total of 309 articles were found in the initial search but only 10 observational studies met the full inclusion criteria. In these studies, 1051 subjects were evaluated for VN, of them 749 were controls and 302 had brain lesions. The two most common types of neuropsychological tools used in children with unilateral brain damage to assess the presence of VN were target cancellation tests and drawing tests. This review confirms the possibility that children with UBL can develop VN, even if it is not very clear which brain structure’s characteristics can increase this risk. Children with right lesion showed visuo-spatial attention deficits focalized on the contralateral side, compatible with diagnosis of VN, while children with left lesion showed more generalized attention difficulties. The overall level of evidence correlating the presence of VN and different types of UBL in children was low and neuropsychological assessment of VN for children are sparse. Some important limitations of this review must be reported: the limited number of studies included, the administration of various types of tests to evaluate VN, the lack of information regarding the cognitive level of children in most of the studies. Further research is needed to understand patterns of VN based on brain structure and time since lesion. Systematic Review Registration: ID on PROSPERO: CRD42021281993
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