462 research outputs found

    Requisiti Minimi per il Trattamento delle Neoplasie Ginecologiche. Società Italiana di Oncologia Ginecologica.

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    L'evoluzione della modulazione della radicalità continuamnete proposta sia per la stadiazione che per l'adeguata exeresi primaria si è arricchita di tecniche di dissezione sempre più accurate e rispettose dei visceri contigui dell'apparato genitale. Questo autorevole contributo della SIOG, oltre a delineare i "requisiti minimi" per il trattamento delle neoplasie ginecologiche, enuncia lo stato dell'arte dell'oncologia ginecologica e sottolinea cultura e professionalità indispensabili per chi aspira ad esserne protagonista

    Current landscape and future perspective of sentinel node mapping in endometrial cancer

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    Endometrial cancer (EC) represents the most common gynecological neoplasm in developed countries. Surgery is the mainstay of treatment for EC. Although EC is characterized by a high prevalence several features regarding its management are still unclear. In particular the execution of lymphadenectomy is controversial. The recent introduction of sentinel node mapping represents the mid-way between the execution and omission of node dissection in EC patients. In the present review we discuss the emerging role of sentinel node mapping in EC. In addition, we discussed how type of tracers utilized and site of injection impacted on sentinel node detection rates. Future perspective regarding EC management are also discussed

    Role of secondary surgery in relapsed ovarian cancer

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    In recurrent ovarian cancer secondary surgery may be an important opportunity to improve survival and quality of life. In order to give a general overview of the available evidence, we discuss published data on the role of secondary surgery in relapsing ovarian cancer. The median survival after secondary surgery has been reported ranging from 16 to 29 months, and seems to be longer in subjects with optimal debulked disease. However, as with front-line debulking, it is difficult to establish whether the secondary debulking itself has a therapeutic, or even a lasting palliative effect, or whether the patients in whom the procedure is successful are those who have more indolent disease. Any benefit of treatment must be compared with potential morbidity. Post-operative complications are reported in about 25–30% of cases, with a potential impact on hospital stay. During the natural course of the disease, most patients with ovarian cancer develop intestinal obstruction, without impairment of other vital organs or pain. Reported series have suggested that palliative surgery for bowel obstruction is generally feasible in most patients. Some prognostic factors have been suggested to identify patients likely to benefit most from palliative surgery: young age seemed to be associated with longer survival after successful surgery for bowel obstruction, though this finding was not statistically significant. The site of obstruction does not seem to be related to survival after surgery
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