724 research outputs found
I Gas Serra nel sottosuolo
No full textLa cattura e lo stoccaggio geologico della CO2 (internazionalmente note come CO2 Capture & Storage = CCS da ora in poi) consistono nell’insieme delle operazioni di carattere industriale in cui la CO2 viene catturata dal camino delle centrali elettriche o prima, vale a dire separata dagli altri gas di combustione, viene poi trasportata compressa e secca all’interno di tubi fino al sito di stoccaggio geologico (pozzi di iniezione che sotto gli 800 m di profondità, vedi Fig. 1), come già discusso su questa rivista (Quattrocchi, 2006).
Quali le novità ? Proprio quando l’ultimo G8 dei primi di giugno a Heiligendamm in Germania, dedica nella sua dichiarazione d’intenti, 15 delle 38 pagine, a clima e energia pulita, e di queste 2 sono dedicate alle tecnologie CCS, e proprio quando in tutto il Mondo i progetti e gli esperimenti di cattura e stoccaggio geologico della CO2, vengono finanziati e attuati con grandi successi (Canada, Norvegia, Germania, Inghilterra, Olanda, etc…), in Italia questa tecnologia, anche solo a farne ricerca al riguardo, è avversata da alcuni consulenti e funzionari di questo Governo (vedi ESPRESSO N. 29, 26 Luglio 2007, pg, 30), senza un ben chiaro motivo: forse un’antica paura di sconvolgimenti sotterranei a seguito dell’iniezione di CO2 in profondità. Tale paura è completamente priva di fondamento, se il sito è scelto con accuratezza, come da circa 30 anni in USA visto che, per motivi di produzione petrolifera (tecnologia ben matura denominata Enhanced Oil Recovery = EOR), si inietta da allora CO2 nel sottosuolo sotto gli 800 metri di profondità, alla pressione in cui cioè la CO2 è allo stato supercritico (si comporta cioè alla stregua di un liquido ed occupa meno volume rispetto a quanto ne occupa, come gas, alle pressioni inferiori).Published14-214.4. Scenari e mitigazione del rischio ambientaleN/A or not JCRreserve
Luigi e Maria Beltrame Quattrocchi. La fecondità del Sacramento vissuto
No full textDi Luigi e Maria Beltrame Quattrocchi, prima coppia beatificata nella storia della Chiesa, viene presentata la vicenda biografica unitamente al cammino di santità percorso nel matrimonio
L’educazione sessuale nella riflessione di Maria Beltrame Quattrocchi
No full textIl contributo presenta la riflessione maturata nei primi anni del Novecento da parte di Maria Beltrame Quattrocchi in merito alla problematica dell'educazione sessuale
“Cercare il meglio sempre” Maria Corsini Beltrame Quattrocchi: la continuità educativa tra famiglia e scautismo
No full textProfilo di Maria Corsini Beltrame Quattrocchi e presentazione dell'impegno educativo e degli scritti di carattere pedagogic
Revealing environmental synchronicity that enhances anchovy recruitment in the Mediterranean Sea
No full textSmall pelagic fishes in the Mediterranean Sea constitute about half of the total landings, of which almost one-third is European anchovy. Anchovy abundance mainly depends on early life stage and juvenile survival and growth, which are susceptible to shifts in environmental processes. Due to the commercial importance of this species, it is necessary to elucidate the processes affecting recruitment strength for effective fishery management, using environmental indices to set more appropriate harvesting limits. Here, we constructed a simple index to capture synchronicity between enrichment and retention/concentration processes, which are known to affect anchovy abundance, during the first year of life. Three ecosystems in the Mediterranean were examined: Gulf of Lions, Adriatic Sea, and Strait of Sicily. The synchronicity index (SI) represented the synergic evolution over time of the chlorophyll-a concentration (CHL, enrichment process) and mixed layer depth (MLD, concentration/retention processes), and was related with the abundance of anchovy recruits obtained from published survey reports. Considering different ecosystems, when the SI was significantly higher, anchovy recruitment was promoted. This result indicated SI is consistent across ecosystems in explaining anchovy abundance fluctuations and thus could be used to enhance fisheries management and extended to assess the impact of projected environmental changes
Discrete-to-continuum limits of optimal transport with linear growth on periodic graphs
No full textWe prove discrete-to-continuum convergence for dynamical optimal transport on Zd
-periodic graphs with cost functional having linear growth at infinity. This result provides an answer to a problem left open by Gladbach, Kopfer, Maas, and Portinale (Calc Var Partial Differential Equations 62(5), 2023), where the convergence behaviour of discrete boundary-value dynamical transport problems is proved under the stronger assumption of superlinear growth. Our result extends the known literature to some important classes of examples, such as scaling limits of 1 -Wasserstein transport problems. Similarly to what happens in the quadratic case, the geometry of the graph plays a crucial role in the structure of the limit cost function, as we discuss in the final part of this work, which includes some visual representations
Identification and characterization of the role of CALR protein and 3’untranslated region in normal and neoplastic hematopoiesis
No full textMyeloproliferative Neoplasms (MPNs) are hematopoietic stem cell-derived clonal disorders including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF), with an overproduction of red blood cells, platelets and bone marrow fibrotic tissue, respectively. MPNs are triggered by JAK2, MPL and CALR (CALR) somatic mutations, all deregulating JAK/STAT signalling. CALR mutations, which are exclusively associated to ET and PMF, generally arise from a +1 frameshift converting the first 31 nucleotides of CALR-3’UTR, into coding sequence. However, the physiologic role of CALR and such CALR-3’UTR region in hematopoiesis are unknown.
This thesis was aimed to: i) investigate the role of CALR in physiological hematopoiesis and the context of MPN; ii) elucidate the function of novel mutated variants of CALR 3’UTR that we identified; iii) realize a model in vitro to study the functional consequences of CALR 3’UTR disruption in myelopoiesis.
Results and conclusions. We observed a hematopoietic lineage- specific regulation of CALR. Moreover, in a cohort of MPN patients, we detected two non-canonical CALR mutations associated to enhanced erythropoiesis in patients diagnosed as JAK2V617F-negative PVs. One was an in frame mutation (c.1214_1225del/del12), whereas the other occurred in the 3’UTR (c.1254+10_+33del/del24). Interestingly, the RNA folding prediction of del24, and even more of del12 indicated a structural impairment of this 3’UTR region. Primary CD34+ cells from such patients exhibited an erythroid growth push on unilineage culture and colony assays, associated with JAK/STAT activation and increase of CALR expression. Strikingly, CALR 3’UTR disruption in myeloid progenitors by CRISPR-CAS9 technology increased CALR levels and JAK/STAT activation, and, more surprisingly, induced erythropoiesis. Overall, these results suggest a novel role for CALR-3’UTR in lineage fate decision of myeloid progenitors. Its disruption might induce a PV-phenotype in vitro and in vivo
A unified model for the mobile-edge-cloud continuum
No full textTechnologies such as mobile, edge, and cloud computing have the potential to form a computing continuum for new, disruptive applications. At runtime, applications can choose to execute parts of their logic on different infrastructures that constitute the continuum, with the goal of minimizing latency and battery consumption and maximizing availability. In this article, we propose A3-E, a unified model for managing the life cycle of continuum applications. In particular, A3-E exploits the Functions-as-a-Service model to bring computation to the continuum in the form of microservices. Furthermore, A3-E selects where to execute a certain function based on the specific context and user requirements. The article also presents a prototype framework that implements the concepts behind A3-E. Results show that A3-E is capable of dynamically deploying microservices and routing the application’s requests, reducing latency by up to 90% when using edge instead of cloud resources, and battery consumption by 74% when computation has been offloaded.Fil: Baresi, Luciano. Politecnico di Milano; ItaliaFil: Mendonça, Danilo Filgueira. Politecnico di Milano; ItaliaFil: Garriga, Martín. Politecnico di Milano; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Guinea, Sam. Politecnico di Milano; ItaliaFil: Quattrocchi, Giovanni. Politecnico di Milano; Itali
Rispettare il processo. Il ruolo sociale, culturale e politico delle ostetriche libere professioniste in Italia e in Spagna
No full textIn this article the author focus on the role of the independent midwives in Italy and
Spain, where she conducted her fieldwork between 2010 and 2015. Emerging data
show that in these contexts – where the medicalisation of childbirth dominates –
independent midwives are today the keepers of the physiology and of the female
knowledge relating to birth. A central concept is “respect”; around this concept orbits
the midwives’ vision of the process and all the practices that are deployed during
the caring process. To beand to dooutside the widespread system allow independent
midwives to critically examine the assumptions and paradigms of scientific medicine,
but also wider social processes. In this sense, a social, a cultural and a political role of
the independent midwives was highlighted
Gino Chierici e l'architettura contemporanea: dal Liberty a Terragni
No full textGino Chierici (1877-1961), soprintendente ai monumenti a Siena, Napoli, Milano, una delle personalità più importanti in Italia nel campo della teoria e della pratica del restauro architettonico, ha avuto anche una limitata ma interessantissima attività come progettista. Il saggio ricostruisce tale attività, dalle realizzazioni Liberty di inizio secolo in provincia di Siena, al convinto sostegno dell'architettura razionalista di Terragni nella Como di fine anni Trenta
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