1,403 research outputs found

    sj-docx-1-cpx-10.1177_21677026221129279 – Supplemental material for Investigating Individual Variation Using Dynamic Structural Equation Modeling: A Tutorial With Tinnitus

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    Supplemental material, sj-docx-1-cpx-10.1177_21677026221129279 for Investigating Individual Variation Using Dynamic Structural Equation Modeling: A Tutorial With Tinnitus by Thomas L. Rodebaugh, Marilyn L. Piccirillo, Madelyn R. Frumkin, Dorina Kallogjeri, Katherine M. Gerull and Jay F. Piccirillo in Clinical Psychological Science</p

    sj-docx-2-aor-10.1177_00034894221104939 – Supplemental material for Balloon Sinus Dilation Versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis

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    Supplemental material, sj-docx-2-aor-10.1177_00034894221104939 for Balloon Sinus Dilation Versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis by Parul Sinha, Theresa Tharakan, Spencer Payne and Jay F. Piccirillo in Annals of Otology, Rhinology & Laryngology</p

    sj-docx-1-aor-10.1177_00034894221104939 – Supplemental material for Balloon Sinus Dilation Versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis

    No full text
    Supplemental material, sj-docx-1-aor-10.1177_00034894221104939 for Balloon Sinus Dilation Versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis by Parul Sinha, Theresa Tharakan, Spencer Payne and Jay F. Piccirillo in Annals of Otology, Rhinology & Laryngology</p

    Blow-up results for a class of first order nonlinear evolution inequalities

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    We investigate the non-existence of solutions to a class of evolution inequalities; in this case, as it happens in a relatively small number of blow-up studies, nonlinearities depend also on time-variable t and spatial derivatives of the unknown. The present results, which in great part do not require any assumption on the regularity of data, are completely new and shown with various applications. Some of these results referring to the problem u t = Δu + a(x) u p + λf(x) in R N , t > 0 include the non-existence results of positive global solutions obtained by Fujita and others when a ≡ 1 and f ≡ 0, Bandle-Levine and Levine-Meier when a ≡ x m and f ≡ 0, Pinsky when either f ≡ 0 or f ≠ > 0 and λ > 0, Zhang and Bandle-Levine-Zhang when a ≡ 1 and λ = 1

    sj-jpg-1-aor-10.1177_00034894221104939 – Supplemental material for Balloon Sinus Dilation Versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis

    No full text
    Supplemental material, sj-jpg-1-aor-10.1177_00034894221104939 for Balloon Sinus Dilation Versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis by Parul Sinha, Theresa Tharakan, Spencer Payne and Jay F. Piccirillo in Annals of Otology, Rhinology & Laryngology</p

    A Randomized Double-Blind Study to Investigate the Clinical Efficacy of Adding a Non-Migrating Antimicrobial to a Special Silk Fabric in the Treatment of Atopic Dermatitis

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    Background: A randomized, double-blind study designed to compare the efficacy of DermaSilk (R) versus a sleeve of similar structure but minus the AEM 5772/5 antimicrobial finish in the treatment of atopic dermatitis (AD). Objective: To evaluate the clinical effect of adding an antimicrobial finish to knitted silk garments on eczema severity and on pruritus in patients with AD. Methods: Thirty patients aged between 3 and 31 years (mean 14.2 +/- 7.7) were enrolled. The inclusion criterion was that the patients presented with active AD with eczematous lesions located on the arms without any sign of infection. Each participant was given a set of 4 pairs of knitted silk tubular sleeves marked with seams of different colours. Only one colour was treated with AEGIS AEM 5772/5. This information was unknown to both the clinicians and the patients/parents. At baseline (T0) and after 7 (T7), 14 (T14), 21 (T21) and 28 (T28) days, the patients were evaluated using the following methods: photographic assessment, local modified SCORAD index adapted for only the arm, and parent/patient assessment of pruritus measured with a visual analogue scale. Results: The mean local SCORAD index of both the DermaSilk- and the unmodified-silk-covered arms decreased significantly between baseline (T0) and the end of study (T28). However, while the DermaSilk group showed a constant decrease each week, the unmodified-silk group showed a significant decrease only in the first 2 weeks of the study. Also the decrease in pruritus values between T0 and T28 was greater for the DermaSilk group. Conclusions: This study demonstrates the importance of including the AEM 5772/5 finish to the specially knitted silk for a long-term improvement of atopic eczema symptoms

    HYPERTRIGLYCERIDEMIA DURING TREATMENT WITH ADALIMUMAB IN PSORIATIC ARTHRITIS

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    A 39-year-old man with a 1-year history of psoriatic arthritis was treated with adalimumab 40 mg every 2 weeks subcutaneously. After 8 weeks of treatment the patient developed hypercholesterolaemia (267 mg/dL), hypertriglyceridaemia (449 mg/)and weakness; we decided to continue treatment and after 3 months of therapy the patient developed a severe weakness and a remarkable hypertriglyceridaemia (689 mg/dL) while total serum cholesterol levels remained unchanged (264 mg/dL). Because of these important alterations we decided to discontinue therapy with the biological drug and after 4 weeks the TG level was 220 mg/dL), cholesterol level was 224 mg/dL) and weakness was notably improved

    Treatment of palmoplantar pustular psoriasis with efalizumab: a quick response with early recurrence

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    A 74-year-old Caucasian man with severe long-standing Palmoplantar pustular psoriasis (PPP) was treated with systemic therapy with efalizumab. Considerable improvement of PPP was observed after only 4 weeks of treatment and a complete recovery of daily activities was obtained after three months of therapy. A month later a sudden important absence of side effects; adult; aged; blood testis barrier; case report; drug withdrawal; human; lab reappearance of pustules were noted. Systemic acitretin at an initial dose of 0.5 mg/kg/d was started while continuing efalizumab. After 15 days an almost complete disappearance of pustular lesions was reobserved. The dermatosis relapsed after suspension of the retinoid, despite ongoing efalizumab

    Transient and slight thrombocytopaenia induced by etanercept during treatment of psoriatic arthritis

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    A 61 years-old male patient suffering from psoriatic arthritis for over 12 years was treated with Etanercept 25 mg subcutaneously twice a week. From the second month of therapy, we observed a decrease of platelet count that achieved the minimal value at the third month of therapy (95 x 103/μl). Being the thrombocytopenia slight and asymptomatic we decided to continue the treatment After the third month of therapy the platelet count gradually increased until the forth month, when the number of platelets recovered the initial value. When we restart the therapy with etanercept,After two months of therapy PASI was 6,4, Ritchie index 3 and a decrease of platelet count was noted achieving the minimal value at the third month of treatment(94,4 x 103/μl)
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