45 research outputs found
Anaesthesia and the QT intervalEffects of isoflurane and halothane in unpremedicated children
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EARLY CARDIAC GENE TRANSCRIPT LEVELS IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF PATIENTS WITH ESSENTIAL HYPERTENSION ASSOCIATE WITH LEFT VENTRICULAR MASS INDEX: PP.22.389
No full textREAL-WORLD EVIDENCE ON LDL-C GOAL ATTAINMENT RATE AND LIPID MANAGEMENT PATTERNS POST-ACS IN GREECE: THE POST-ACUTE CORONARY SYNDROME STUDY (PACSS)
No full textEstimation of the economic burden of atrial fibrillation-related stroke in Greece
No full textBackground: Stroke is aleading cause of death and disability, with atrial fibrillation (AF) being among key risk factors and AF-related stroke inflicting significant burden on healthcare systems and society. The present study was undertaken for estimating the total annual socioeconomic burden of AF-related stroke in Greece and identifying the key cost contributors. Research design and methods: A cost-of-illness model was developed for estimating the total annual economic burden of AF-related stroke in Greece, from asocietal perspective (year 2018). Atargeted literature review and an advisory board consisting of key experts in the management of AF and AF-related stroke were performed for collecting local resource use and epidemiological data. Results: The total annual socioeconomic burden of AF-related stroke was estimated at €175million, in 2018. Direct and indirect costs accounted for 59% and 41%, respectively. Main contributors were informal care (21.1%), patients’ productivity losses (19.7%) and hospitalizations (15.0%), accounting for more than half of the total costs of AF-related stroke events. Conclusion: A F-related stroke imposes asignificant socioeconomic burden in Greece. Despite results relying on estimations, it seems that ensuring efficient reallocation of resources in appropriate prevention and early intervention strategies could decrease AF-related stroke’s burden but also enhance healthcare systems’ efficiency. Abbreviations: AF=atrial fibrillation. © 2021 Informa UK Limited, trading as Taylor & Francis Group
The role of angiotensin-(1-7)/mas axis and angiotensin type 2 receptors in the central nervous system in cardiovascular disease and therapeutics: A riddle to be solved
No full textIn recent years, the Angiotensin-(1-7)/Mas receptor [Ang-(1-7)/Mas] sub-branch of the Renin-Angiotensin System (RAS) in the brain, and Angiotensin Type 2 Receptors (AT2R), have attracted scientific interest, as there is evidence that they constitute an essential pathway in cardiovascular regulation, in health and in disease. By acting centrally, the Ang-(1-7)/Mas axis-that has been termed ‘the axis of good’-can exert blood pressure-lowering effects, while also favourably altering baroreflex sensitivity and noradrenergic neurotransmission. Thus, research has focused on the possible neuro-and cardioprotective effects of this pathway in the setting of cardiovascular disease, ultimately aiming to evaluate the potential for development of novel therapeutic strategies based on its modulation. We summarize the available evidence from experimental studies in this context, aiming to assess current limits of scientific knowledge relevant to this newly-described ‘player’ in haemodynamic regulation, that may become a potential therapeutic target. © 2019 Bentham Science Publishers
Impact of atrioventricular delay on heart rate variability of paced patients with and without heart failure
No full textEstimation of the economic burden of atrial fibrillation-related stroke in Greece
No full textBackground: Stroke is aleading cause of death and disability, with atrial fibrillation (AF) being among key risk factors and AF-related stroke inflicting significant burden on healthcare systems and society. The present study was undertaken for estimating the total annual socioeconomic burden of AF-related stroke in Greece and identifying the key cost contributors. Research design and methods: A cost-of-illness model was developed for estimating the total annual economic burden of AF-related stroke in Greece, from asocietal perspective (year 2018). Atargeted literature review and an advisory board consisting of key experts in the management of AF and AF-related stroke were performed for collecting local resource use and epidemiological data. Results: The total annual socioeconomic burden of AF-related stroke was estimated at euro175million, in 2018. Direct and indirect costs accounted for 59% and 41%, respectively. Main contributors were informal care (21.1%), patients’ productivity losses (19.7%) and hospitalizations (15.0%), accounting for more than half of the total costs of AF-related stroke events. Conclusion: A F-related stroke imposes asignificant socioeconomic burden in Greece. Despite results relying on estimations, it seems that ensuring efficient reallocation of resources in appropriate prevention and early intervention strategies could decrease AF-related stroke’s burden but also enhance healthcare systems’ efficiency
LONG NON CODING RNAS IN PERIPHERAL BLOOD MONONUCLEAR CELLS IN HYPERTENSIVES WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION AND THEIR RELATION TO THEIR FUNCTIONAL CAPACITY
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