17,465 research outputs found
Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components
No full textIn many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla. In the silkworm Bombyx mori, the OBPs are subdivided into three main subfamilies; pheromone-binding proteins (PBPs), general odorant-binding proteins (GOBPs) and antennal-binding proteins (ABPs). We used the MotifSearch algorithm to search for genes encoding putative OBPs in B. mori and found 13, many fewer than are found in the genomes of fruit flies and mosquitoes. The 13 genes include seven new ABP-like OBPs as well as the previously identified PBPs (three), GOBPs (two) and ABPx. Quantitative examination of transcript levels showed that BmorPBP1, BmorGOBP1, BmorGOBP2 and BmorABPx are expressed at very high levels in the antennae and so could be involved in olfaction. A new two-phase binding assay, along with other established assays, showed that BmorPBP1, BmorPBP2, BmorGOBP2 and BmorABPx all bind to the B. mori sex pheromone component (10E,12Z)-hexadecadien-1-ol (bombykol). BmorPBP1, BmorPBP2 and BmorABPx also bind the pheromone component (10E,12Z)-hexadecadienal (bombykal) equally well, whereas BmorGOBP2 can discriminate between bombykol and bombykal. X-ray structures show that when bombykol is bound to BmorGOBP2 it adopts a different conformation from that found when it binds to BmorPBP1. Binding to BmorGOBP2 involves hydrogen bonding to Arg110 rather than to Ser56 as found for BmorPBP1
La libertà umana. Storia di una controversia filosofica
No full textSaggi di M. De Caro, L. Fonnesu, G. Lettieri, M. Mori, C. Natali, P. Porro, E. Spinelli, F. Trabatton
Redevelopment after the Abruzzo event
No full textNatural disasters raise quite a number of interdisciplinary issues concerning regional economic growth and local development, as well as public finance and sustainability, to mention only a few of them. These issues deserve special attention in our globalized world, given the expectation of a growing impact of climate-related disasters: no surprise that disaster management stands as a new discipline aimed at bridging the gap between theory and practice, so as to prevent natural disasters in the first place; afterwards, considerable efforts are required to accelerate business recovery, quickly restore vital energies, and hopefully carry out specific improvement projects as a sort of compensation for the (both personal and economic) losses suffered. Interesting lessons can be learned from natural disasters and can be shared as a payback to those who helped upon their occurrence. Actually, cooperation calls for cross-cultural activities that are likely to benefit from direct experience made by impacted scholars and practitioners: a case in point has to do with the earthquake that devastated L’Aquila and its environs on April 6, 2009 causing more than 300 deaths, apart from extensive damage in the Abruzzo region, in Central Italy; the Abruzzo event – as this natural disaster is currently referred to – fuels the debate on redevelopment problems to be faced under similar circumstances, that may obliterate the economic environment and attractiveness of an area in a few moments. Due to the huge amount of money needed to undertake appropriate strategies, finance plays a key role and useful insights can be gained by exploring the process of financial innovation. A supporting argument deals with the recourse to micro-finance in order to make the business and economic scenario revive after a natural disaster: micro-credit might be resorted to even within the framework of new financial engineering instruments, such as Urban Development Funds, recently promoted by the European Investment Bank; they include JESSICA (Joint European Support for Sustainable Investment in City Areas) and JEREMIE (Joint European Resources for Micro to Medium Enterprises), to be properly considered as strategic tools in sight of redeveloping L’Aquila and its surrounding boroughs.
Short interval intracortical facilitation correlates with the degree of disability in multiple sclerosis
No full textMori F, Kusayanagi H, Monteleone F, et al. Short interval intracortical facilitation correlates with the degree of disability in multiple sclerosis. Brain Stimulation. 2013;6(1):67-71
I mondi intermedi degli esercizi spirituali: percorsi storico-filosofici
No full text1. Premessa sui mondi intermedi
2. La Tavola di Cebete e la caverna di Platone
3. Sul ricorso alla simulazione nello Stoicismo romano
4. Altre finestre sui mondi intermedi degli esercizi spiritual
A NOTE ON THE STRONGLY MORI DOMAINS
No full textWe will prove that there is no Mori domain which is a Krull domain and Strongly Mori domain. And we construct a Mori domain A; Let V be a valuation domain with maximal ideal M ≠ (0).
◁그림 삽입▷ (원문을 참조하세요)
, where π is the canonical surjection and F' is a subring of the field F. We will prove that A is a Strongly Mori domain if and only if, V is a DVR ( discrete valuation ring) and F' is a proper subfield of F. Moreover, we will give an example of Mori domain, which is neither Krull domain nor Strongly Mori domain.;Krull domain 으로서 Strongly Mori domain이 되는 Mori domaim이 존재하지 않는 것을 증명한다. V를 maximal ideal M을 갖는 valuation domain이라 하고 다음과 같이 Mori domain A를 만든다.
◁그림참조▷(원본을 참조하세요)
이때 π는 canonical surjection이고 F'은 체F의 부분환이다. A가 Strongly Mori domain이기 위한 필요충분조건은 V가 DVR이고 F'이 체F의 진부분체인 것을 보인다.
또한 Krull domain도 아니고 Strongly Mori domain도 아닌 Mori domain을 예로 보여준다.ABSTRACT = ⅰ
CONTENTS = ⅱ
INTRODUCTION = ⅲ
Ⅰ. PRELIMINARIES = 1
Ⅱ. CONSTRUCTION OF STRONGLY MORI DOMAIN = 5
REFERENCES = 10
논문초록 = 1
Filosofia come palestra del pensiero, a partire dall’infanzia
No full textIl capitolo affronta il problema dell'educazione del senso del limite attraverso la conversazione filosofica, a partire dalla sentenza "Nulla di troppo", attribuita a Solone, con una prospettiva al tempo stesso filosofica e pedagogica. Facendo riferimento a Wittgenstein, si considera la possibilità di rilevare caratteristiche peculiari e distintive delle domande filosofiche e del rapporto tra argomentazione ed esperienza nei tentativi di rispost
Improved performance of submicrometer-gate GaAs MESFET's with an Al0.3Ga0.7As buffer layer grown by metal organic vapor phase epitaxy
No full text- …
