147 research outputs found
Measurement of the branching ratio of the decay D-0 ->pi(-)mu(+)nu relative to D-0 -> K-mu(+)nu
No full textAbstractWe present a new measurement of the branching ratio of the Cabibbo suppressed decay D0→π−μ+ν relative to the Cabibbo favored decay D0→K−μ+ν and an improved measurement of the ratio |f+π(0)/f+K(0)|. Our results are 0.074±0.008±0.007 for the branching ratio and 0.85±0.04±0.04±0.01 for the form factor ratio, respectively
Analysis of the decay mode D0 → K−mu+nu(mu)
No full textStudies of the decay D0 + K-mu+ nu, are reported by Fermilab photoproduction experiment E687. The ratio BR( D0 ->
K-mu+ nu(mu),)/BR( D0 -> K-pi+) is determined to be 0,852 +- 0.034 (statistical) +- 0.028 (systematic). Using this result and
an isospin argument we infer the ratio BR(D0 -> K*-,mu+ nu(mu))/BR(D0->K- mu+ nu(mu)) = 0.62+- 0.07+- 0.09. The pole
mass from the single pole form factor is measured to be M(pole) = l.87(-0.08-0.06)(+0.11+0.07) GeV/c2. Using M(pole) and BR( D0->
K-,mu+ nu(mu))/BR(D0->K-pi+), we calculate |f+(O)| = 0.71 +-0.03+-0.03. We also measure the ratio f-(0)/f+(O) =
- 1.3(-3.4)(+3.6) +- 0.
Measurements of the q(2) dependence of the D-0 -> K-mu(+)nu and D-0 -> K-mu(+)nu and D-0 -> pi(-)mu(+)nu form factors
No full textUsing a large sample of D0 → K−μ+ν and D0 → π−μ+ν decays collected by the FOCUS photoproduction experiment
at Fermilab, we present new measurements of the q2 dependence for the f+(q2) form factor. These measured f+(q2) form
factors are fit to common parameterizations such as the pole dominance form and compared to recent unquenched Lattice QCD
calculations. We find mpole = 1.93 ± 0.05 ± 0.03 GeV/c2 for D0 → K−μ+ν and mpole = 1.91+0.30 ± 0.07 GeV/c2 for
D0 → π−μ+ν and f (K)(0)/f (K)(0) = −1.7+1.5 ± 0.3. − + −1.
Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy
No full text"
Objectives: We aim to investigate cognitive phenotype distribution and MRI correlates across pediatric-, elderly-, and adult-onset MS patients as a function of disease duration.
Methods: In this cross-sectional study, we enrolled 1262 MS patients and 238 healthy controls, with neurological and cognitive assessments. A subset of 222 MS patients and 92 controls underwent 3T-MRI scan for brain atrophy and lesion analysis. Multinomial probabilistic models identified likelihood of belonging to cognitive phenotypes (""preserved-cognition,"" ""mild verbal memory/semantic fluency,"" ""mild multi-domain,"" ""severe attention/executive,"" and ""severe multi-domain"") and experiencing MRI abnormalities based on disease duration and age at onset.
Results: In all groups, the likelihood of ""preserved-cognition"" phenotype decreased, whereas ""mild multi-domain"" increased with longer disease duration. In pediatric- and adult-onset patients, the likelihood of ""mild verbal memory/semantic fluency"" phenotypes decreased with longer disease duration, and that of ""severe multi-domain"" increased with longer disease duration. Only in adult-onset patients, the likelihood of ""severe executive/attention"" phenotype increased with longer disease duration. All groups displayed escalating probabilities of cortical, thalamic, hippocampal, and deep gray matter atrophy over disease course. Compared to adult, pediatric-onset patients showed lower probability of experiencing thalamic atrophy with longer disease duration, while elderly-onset showed higher probability of experiencing cortical and hippocampal atrophy.
Interpretation: Age at MS onset significantly influences the distribution of cognitive phenotypes and the patterns of regional gray matter atrophy throughout the disease course.
ChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis
No full textBackground: ChatGPT is an open-source natural language processing software that replies to users' queries. We conducted a cross-sectional study to assess people living with Multiple Sclerosis' (PwMS) preferences, satisfaction, and empathy toward two alternate responses to four frequently-asked questions, one authored by a group of neurologists, the other by ChatGPT. Methods: An online form was sent through digital communication platforms. PwMS were blind to the author of each response and were asked to express their preference for each alternate response to the four questions. The overall satisfaction was assessed using a Likert scale (1-5); the Consultation and Relational Empathy scale was employed to assess perceived empathy. Results: We included 1133 PwMS (age, 45.26 ± 11.50 years; females, 68.49%). ChatGPT's responses showed significantly higher empathy scores (Coeff = 1.38; 95% CI = 0.65, 2.11; p > z < 0.01), when compared with neurologists' responses. No association was found between ChatGPT' responses and mean satisfaction (Coeff = 0.03; 95% CI = - 0.01, 0.07; p = 0.157). College graduate, when compared with high school education responder, had significantly lower likelihood to prefer ChatGPT response (IRR = 0.87; 95% CI = 0.79, 0.95; p < 0.01). Conclusions: ChatGPT-authored responses provided higher empathy than neurologists. Although AI holds potential, physicians should prepare to interact with increasingly digitized patients and guide them on responsible AI use. Future development should consider tailoring AIs' responses to individual characteristics. Within the progressive digitalization of the population, ChatGPT could emerge as a helpful support in healthcare management rather than an alternative
ChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis
No full textBackground ChatGPT is an open-source natural language processing software that replies to users' queries. We conducted a cross-sectional study to assess people living with Multiple Sclerosis' (PwMS) preferences, satisfaction, and empathy toward two alternate responses to four frequently-asked questions, one authored by a group of neurologists, the other by ChatGPT. Methods An online form was sent through digital communication platforms. PwMS were blind to the author of each response and were asked to express their preference for each alternate response to the four questions. The overall satisfaction was assessed using a Likert scale (1-5); the Consultation and Relational Empathy scale was employed to assess perceived empathy. Results We included 1133 PwMS (age, 45.26 +/- 11.50 years; females, 68.49%). ChatGPT's responses showed significantly higher empathy scores (Coeff = 1.38; 95% CI = 0.65, 2.11; p > z < 0.01), when compared with neurologists' responses. No association was found between ChatGPT' responses and mean satisfaction (Coeff = 0.03; 95% CI = - 0.01, 0.07; p = 0.157). College graduate, when compared with high school education responder, had significantly lower likelihood to prefer ChatGPT response (IRR = 0.87; 95% CI = 0.79, 0.95; p < 0.01). Conclusions ChatGPT-authored responses provided higher empathy than neurologists. Although AI holds potential, physicians should prepare to interact with increasingly digitized patients and guide them on responsible AI use. Future development should consider tailoring AIs' responses to individual characteristics. Within the progressive digitalization of the population, ChatGPT could emerge as a helpful support in healthcare management rather than an alternative
Neural network based reconstruction of neutral hadrons in a fixed target photoproduction experiment
No full textA wide band photon beam at the Fermilab Tevatron to study heavy flavors
No full textFor many years, the use of high energy photon beams has been recognized as a good technique for the investigation of charmed particles [1]. The cross section is a relatively large fraction (approximately 1%) of the total hadronic cross section at high energies. The challenge was to develop a high energy and high intensity beam that produces enough charmed particles to obtain very high statistics so that one can answer detailed questions about charm production and decays. The Fermilab wide band photon beam is an attempt to meet that challenge. The beamline configuration and capabilities have evolved since the test run in 1985 and the first physics run in 1987-88. For the 1990-91 data run, improvements were made to increase the photon yield and to improve the photon energy tagging resolution. Althought the main emphasis of this report is on the original 1985-88 beam configuration, two fully operational upgrades for the 1990-91 run, namely the incident electron beam momentum tagging spectrometer and the LD2 primary beam target, are described. The beam was also given the capability of transporting simultaneously e+ and e- beams. The performance of this ''double-band'' configuration was studied briefly duing the 1990-91 running period and will be described in a future publication. A description of the Fermilab E687 spectrometer utilizing this photon beam facility has recently been published [2]
Study of D0→Ks0 π+π− and D0→Ks0 K+K− in high energy photoproduction
No full textAnalysis of the resonant and non-resonant branching fractions for the decays D0→KS0π+π−and D0→KS0K+K− is presented. For the D0→KS0π+π− decay, a fit to the observed Dalitz plot was performed to determine the complex amplitudes of the sub-component modes. For the D0→KS0K+K− decay, measurements of the branching ratios D0→KS0K+K− (inclusive), D0→KS0φ, and D0→KS0(K+K−)non-φ relative to the D0→KS0π+π− mode are reported. The data were collected by the Fermilab high energy photoproduction experiment E687
Study of charged hadronic five-body decays of the D+ and Ds+ mesons
No full textCharged hadronic five-body decays of D+ and Ds+ mesons have been studied in the E687 photoproduction experiment at Fermilab. We report the first compelling evidence of the decay mode D+, Ds+ → pi−pi−pi+pi+pi+ and the measurements of the decays D+ → K−pi−pi+pi+pi+, Ds+ → K−K+pi−pi+pi+ and Ds+ → phi pi−pi+pi+. An analysis of the D+ → K−pi−pi+pi+pi+ resonance structure is also presente
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