114 research outputs found
Author Correction: A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity (Nature Communications, (2022), 13, 1, (5104), 10.1038/s41467-022-3
No full textIn the author list of this article, the names of the authorswere incorrectly listed with initials and family name only. The incorrect author list read as “C. Kedor, H. Freitag, L. Meyer-Arndt, K. Wittke, L. G. Hanitsch, T. Zoller, F. Steinbeis, M. Haffke, G. Rudolf, B. Heidecker, T. Bobbert, J. Spranger, H. D. Volk, C. Skurk, F. Konietschke, F. Paul, U. Behrends, J. Bellmann-Strobl and C. Scheibenbogen”. The author list has now been amended to include the given and family names in the HTML and PDF versions of the article. The corrected author list reads as “Claudia Kedor, Helma Freitag, Lil Meyer-Arndt, Kirsten Wittke, Leif G. Hanitsch, Thomas Zoller, Fridolin Steinbeis, Milan Haffke, Gordon Rudolf, Bettina Heidecker, Thomas Bobbert, Joachim Spranger, Hans- Dieter Volk, Carsten Skurk, Frank Konietschke, Friedemann Paul, Uta Behrends, Judith Bellmann-Strobl and Carmen Scheibenbogen”
Intra- and interobserver reliability of glenoid fracture classifications by Ideberg, Euler and AO
No full textBackground:
Representing 3%-5% of shoulder girdle injuries scapula fractures are rare. Furthermore, approximately 1% of scapula fractures are intraarticularfractures of the glenoid fossa. Because of uncertain fracture morphology and limited experience, the treatment of glenoid fossa fractures is difficult. The glenoid fracture classification by Ideberg (1984) and Euler (1996) is still commonly used in literature. In 2013 a new glenoid fracture classification was introduced by the AO. The purpose of this study was to examine the new AO classification in clinical practice in comparison with the classifications by Ideberg and Euler.
Methods:
In total CT images of 84 patients with glenoid fossa fractures from 2005 to 2018 were included. Parasagittal, paracoronary and axial reconstructions were examined according to the classifications of Ideberg, Euler and the AO by 3 investigators (orthopedic surgeon, radiologist, student of medicine) at three individual time settings. Inter- and intraobserver reliability of the three classification systems were ascertained by computing Inter- and Intraclass (ICCs) correlation coefficients using Spearman's rank correlation coefficient, 95%-confidence intervals as well as F-tests for correlation coefficients.
Results:
Inter- and intraobserver reliability for the AO classification showed a perspicuous coherence (R = 0.74 and R = 0.79). Low to moderate intraobserver reliability for Ideberg (R = 0.46) and Euler classification (R = 0.41) was found. Furthermore, data show a low Interobserver reliability for both Ideberg and Euler classification (R < 0.2). Both the Inter- and Intraclass reliability using AO is significantly higher than those using Ideberg and Euler (p < 0.05). Using the new AO classification, it was possible to find a proper class for every glenoid fossa fracture. On average, according to Euler classification 10 of 84 fractures were not classifiable whereas to Ideberg classification 21 of 84 fractures were not classifiable.
Conclusion:
The new AO classification system introduced 2013 facilitates reliable grading of glenoid fossa fractures with high inter- and intraobserver reliability in 84 patients using CT images. It should possibly be applied in order to enable a valid, reliable and consistent academic description of glenoid fossa fractures. The established classifications by Euler and Ideberg are not capable of providing a similar reliability
Planning and Real Time Control of a Minimally Invasive Robotic Surgery System
No full textThis paper introduces the planning and control software of a teleoperating robotic system for minimally invasive surgery. It addresses the problem of how to organize a complex system with 41 degrees of freedom including robot setup planning, force feedback control and nullspace handling with three robotic arms. The planning software is separated into sequentially executed planning and registration procedures. An optimal setup is first planned in virtual reality and then adapted to variations in the operating room. The real time control system is composed of hierarchical layers. The design is flexible and expandable without losing performance. Structure, functionality and implementation of planning and control are described. The robotic system provides the surgeon with an intuitive hand-eye-coordination and force feedback in teleoperation for both hands
Nonparametric multiple comparisons and simultaneous confidence intervals for multivariate designs
No full text
User Guide for Biometric Planning of Animal Trials
No full textThis booklet is an appendix to:
Piper, S. K., Zocholl, D., Toelch, U., Roehle, R., Stroux, A., Hoessler, J., Zinke, A., & Konietschke, F. (2022). Statistical review of animal trials—A guideline. Biometrical Journal, 00, 00–00. https://doi.org/10.1002/bimj.20220006
Distribution-free multivariate inference about diagnostic classifiers based on partial areas under their receiver operating characteristic curves
No full textEfficacy of D-RaCe and ProTaper Universal Retreatment NiTi instruments and hand files in removing gutta-percha from curved root canals - a micro-computed tomography study
No full textRodig T, Hausdorfer T, Konietschke F, Dullin C, Hahn W, Hulsmann M. Efficacy of D-RaCe and ProTaper Universal Retreatment NiTi instruments and hand files in removing gutta-percha from curved root canals a micro-computed tomography study. International Endodontic Journal, 45, 580589, 2012. Abstract Aim To compare the efficacy of two rotary NiTi retreatment systems and Hedstrom files in removing filling material from curved root canals. Methodology Curved root canals of 57 extracted teeth were prepared using FlexMaster instruments and filled with gutta-percha and AH Plus. After determination of root canal curvatures and radii in two directions, the teeth were assigned to three identical groups (n = 19). The root fillings were removed with D-RaCe instruments, ProTaper Universal Retreatment instruments or Hedstrom files. Pre- and postoperative micro-CT imaging was used to assess the percentage of residual filling material as well as the amount of dentine removal. Working time and procedural errors were recorded. Data were analysed using analysis of covariance and analysis of variance procedures. Results D-RaCe instruments were significantly more effective than ProTaper Universal Retreatment instruments and Hedstrom files (P < 0.05). Hedstrom files removed significantly less dentine than the rotary NiTi systems (P < 0.0001). D-RaCe instruments were significantly faster compared to both other groups (P < 0.05). No procedural errors such as instrument fracture, blockage, ledging or perforation were detected in the Hedstrom group. In the ProTaper group, four instrument fractures and one lateral perforation were observed. Five instrument fractures were recorded for D-RaCe. Conclusions D-RaCe instruments were associated with significantly less residual filling material than ProTaper Universal Retreatment instruments and hand files. Hedstrom files removed significantly less dentine than both rotary NiTi systems. Retreatment with rotary NiTi systems resulted in a high incidence of procedural errors
A Comparison of Efficient Permutation Tests for Unbalanced Anova in Two by Two Designs and Their Behavior Under Heteroscedasticity
No full textWe outlined various procedures that aim to compensate shortcomings of classical
ANOVA. Some procedures are only valid under normality and possibly
heteroscedastic variances (ATS). CSP and USP are valid under non-normally
distributed error terms and homoscedastic variances. Both the WTS and WTPS are
asymptotically valid even under non-normality and heteroscedasticity, respectively.
Most of these procedures are intended to be used for small samples (ATS, WTPS,
CSP, and USP), only the WTS requires a sufficiently large sample size.
In the following simulation we vary additionally the aspect of balanced vs.
unbalanced designs, as heteroscedasticity is especially problematic in the latter one
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