95 research outputs found
Full-Wave Simulation of a Helmholtz Radiofrequency Coil for Magnetic Resonance Applications
No full textMagnetic resonance imaging (MRI) is a non-invasive diagnostic technique able to provide information about the anatomical, structural, and functional properties of different organs. A magnetic resonance (MR) scanner employs radiofrequency (RF) coils to generate a magnetic field to excite the nuclei in the sample (transmit coil) and pick up the signals emitted by the nuclei (receive coil). To avoid trial-and-error approaches and optimize the RF coil performance for a given application, accurate design and simulation processes must be performed. We describe the full-wave simulation of a Helmholtz coil for high-field MRI performed with the finite-difference time-domain (FDTD) method, investigating magnetic field pattern differences between loaded and unloaded conditions. Moreover, the self-inductance of the single loops constituting the Helmholtz coil was estimated, as well as the frequency splitting between loops due to inductive coupling and the sample-induced resistance. The result accuracy was verified with data acquired with a Helmholtz prototype for small phantom experiments with a 3T MR clinical scanner. Finally, the magnetic field variations and coil detuning after the insertion of the RF shield were evaluated
A Novel Magnetic Resonance Phased-Array Coil Designed with FDTD Algorithm
No full textRadio-frequency receiver phased-array coils in magnetic resonance imaging systems are used to pick up the signals emitted by the nuclei with high signal-to-noise ratio and a large region of sensitivity. Since the quality of obtained images strongly depends upon the correct choice of the coil geometry and position, array coils have to be designed by minimizing the mutual interaction among nearby coil elements and this is generally achieved by overlapping such adjacent elements. In this paper, we describe the use of a numerical solver based on finite-difference time-domain method to determine the optimal overlap distance, which guarantees the maximum decoupling level between the coil loops, for array coils constituted by various geometry elements. A novel array coil was designed, constituted by a couple of elliptical geometry elements in "folding" version around the animals' spine curvature, for small animals' imaging applications
The human olfactory system: stimulation with fMRI and group analysis in healthy subjects
No full textIntegration of EEG and fMRI for the localization of cortical sources of neural activation
No full textIntegration of EEG and fMRI for the localization of cortical sources of neural activation
No full textDiffusion tensor MRI and MR spectroscopy in long lasting upper motor neuron involvement in amyotrophic lateral sclerosis
No full textA Practical Guide to Estimating Coil Inductance for Magnetic Resonance Applications
No full textRadiofrequency (RF) coils are employed to transmit and/or receive signals in Magnetic Resonance (MR) systems. The design of home-made, organ-specific RF coils with optimized homogeneity and/or Signal-to-Noise Ratio (SNR) can be a plus in many research projects. The first step requires accurate inductance calculation, this depending on the conductor’s geometry, to later define the tuning capacitor necessary to obtain the desired resonance frequency. To fulfil such a need it is very useful to perform a priori inductance estimation rather than relying on the time-consuming trial-and-error approach. This paper describes and compares two different procedures for coil inductance estimation to allow for a fast coil-prototyping process. The first method, based on calculations in the quasi-static approximation, permits an investigation on how the cross-sectional geometry of the RF coil conductors affects the total inductance and can be easily computed for a wide variety of coil geometries. The second approach uses a numerical full-wave method based on the Finite-Difference Time-Domain (FDTD) algorithm, and permits the simulation of RF coils with any complex geometry, including the case of multi-element phased array. Comparison with workbench measurements validates both the analytical and numerical results for RF coils operating within a wide field range (0.18–7 T)
Plasticity of the human visual brain after an early cortical lesion
No full textIn adults, partial damage to V1 or optic radiations abolishes perception in the corresponding part of the visual field, causing a scotoma. However, it is widely accepted that the developing cortex has superior capacities to reorganize following an early lesion to endorse adaptive plasticity. Here we report a single patient case (G.S.) with near normal central field vision despite a massive unilateral lesion to the optic radiations acquired early in life. The patient underwent surgical removal of a right hemisphere parieto-temporal-occipital atypical choroid plexus papilloma of the right lateral ventricle at four months of age, which presumably altered the visual pathways during in utero development. Both the tumor and surgery severely compromised the optic radiations. Residual vision of G.S. was tested psychophysically when the patient was 7 years old. We found a close-to-normal visual acuity and contrast sensitivity within the central 25° and a great impairment in form and contrast vision in the far periphery (40-50°) of the left visual hemifield. BOLD response to full field luminance flicker was recorded from the primary visual cortex (V1) and in a region in the residual temporal-occipital region, presumably corresponding to the middle temporal complex (MT+), of the lesioned (right) hemisphere. A population receptive field analysis of the BOLD responses to contrast modulated stimuli revealed a retinotopic organization just for the MT+ region but not for the calcarine regions. Interestingly, consistent islands of ipsilateral activity were found in MT+ and in the parieto-occipital sulcus (POS) of the intact hemisphere. Probabilistic tractography revealed that optic radiations between LGN and V1 were very sparse in the lesioned hemisphere consistently with the post-surgery cerebral resection, while normal in the intact hemisphere. On the other hand, strong structural connections between MT+ and LGN were found in the lesioned hemisphere, while the equivalent tract in the spared hemisphere showed minimal structural connectivity. These results suggest that during development of the pathological brain, abnormal thalamic projections can lead to functional cortical changes, which may mediate functional recovery of vision
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