1,721,263 research outputs found

    COUMARIN-BASED OR MELILOT-BASED TRANSDERMAL PLASTERS

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    Transdermal plaster containing melilot or coumarin as the active ingredient, comprising: a) an impermeable substrate layer; b) an adhesive layer containing the active principle dispersed therein and containing as the adhesive polymer an acrylic polymer selected from the group consisting of: (I) a mixture of: the cationic copolymer (b-1) dimethylamino-ethyl-methacrylate / neutral ester of methacrylic acid with one or more C1-C10 alcohols, the neutral copolymer (b-1-(i)) ethyl acrylate / methyl methacrylate, or else (II) an anionic copolymer (b-1(ii)) methacrylic acid / methyl methacrylate, said adhesive layer (b) moreover comprising the following components: b-2) glycerine, b-3) polyethylene glycol 400; c) a protective film which may be removed just before use

    MOUTHWASH IN THE FORM OF A STABLE SUSPENSION COMPRISING MICROSPHERES THAT INCORPORATE AN ACTIVE INGREDIENT

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    The present invention relates to a mouthwash comprising microspheres that incorporate an active ingredient, characterized in that the microspheres are obtained directly in situ in the aqueous phase of the mouthwash by cross-linking. These microspheres do not tend to aggregate and the mouthwash appears in the form of a homogenous and stable suspension even after prolonged storage

    PATCH FOR LOCAL AND TRANSDERMAL ADMINISTRATION OF ACTIVE INGREDIENTS CONTAINING ANIONIC OR ELECTRON-ATTRACTING GROUPS

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    Bioadhesive microspheres containing proximate principles dispersed in a polymeric matrix are suitable for the sublingual administration of the same

    THREE-DIMENSIONAL SCAFFOLD CONSISTING OF FIBROIN AND POLYETHYLENE USEFUL FOR CELL CULTURES

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    Disclosed are spongy structures with interconnected pores consisting of fibroin from Bombyx mori and polyethylene glycol with a molecular weight of less than 1500, in the fibroin/polyethylene glycol ratio of between 99: 1 and 90: 10 parts, obtained by regenerating fibroin, mixing with polyethylene glycols, freeze-drying in aqueous solution in the absence of organic solvents, and sterilising under saturated steam

    Collutorio In Forma Di Sospensione Stabile Comprendente Microsfere Che Incorporano Un Principio Attivo.

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    The present invention relates to a mouthwash including microspheres that incorporate an active ingredient, wherein the microspheres are obtained directly in situ in the aqueous phase of the mouthwash by cross-linking. These microspheres do not tend to aggregate and the mouthwash appears in the form of a homogenous and stable suspension even after prolonged storage

    FAST RELEASE BIOADHESIVE MICROSPHERES FOR THE SUBLINGUAL ADMINISTRATION OF PROXIMATE PRINCIPLES

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    Bioadhesive microspheres containing proximate principles dispersed in a polymeric matrix are suitable for the sublingual administration of the same

    Transdermal patches having a siliconic adhesive matrix stabilized with methacrylic copolymers

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    Patch suitable for transdermal or local administration of active principles s comprising: (a) a matrix based on pressure sensitive adhesive silicone polymers containing: (a-1) said active principle in concentrations between 1 and 10% by weight on the, total weight of said DEG dry adhesive matrix, (a-2) said silicone polymers in quantities, between 80 and 98% by,weight on the io total weight of said DEG dry adhesive matrix, (a-3) a copolymer of cationic type of acrylic and/or methacrylic esters containing amino groups or salified ammonium groups in a concentration between 1 and 10% by weight on the total weight of said adhesive silicone polymers, (b) a support layer on which said adhesive matrix (a) is located, (c) a protective layer disposed on said adhesive matrix and removable on use

    MEDICATED PATCH FOR IMPROVED TRANSDERMAL PERMEATION OF DICLOFENAC DIETHYLAMMONIUM

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    A medicated patch for improved transdermal permeation of diclofenac diethylammonium in a composition comprising an acrylic copolymer and a citric acid ester

    Aqueous Polymeric System for Pressure Sensitive Adhesive Matrix Preparation

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    A water based polymeric dispersion for PSA adhesive preparation for transdermal system comprising: a) an aqueous dispersion of a polymer of an acrylate and/or a methacrylate ester, b) a plasticizer c) a shrinkage reducing agent able to reduce the shrinkage of the water PSA dispersion when spread onto a surface to width values lower than 20 mm after 3 minutes rest
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