1,077 research outputs found
Ritornare a Salemi
No full textPubblicato originariamente nel 1984, con una prima ristampa nel 1987, questo
bellissimo libro offriva, attraverso le fotografie di Mimmo Jodice e i testi di
Francesco Venezia, una ricca documentazione tematica e una interpretazione
originale dei caratteri architettonici e paesaggistici di Salemi. Nella fertile
complicità tra fotografo e architetto il libro invitava al viaggio. Anche se le condizioni di vita sono oggi profondamente cambiate rispetto agli
anni ’80, obbligando a pensare a nuovi scenari di trasformazione, rimangono
profondamente attuali sia le fotografie di Mimmo Jodice, che ben rappresentano
alcuni caratteri invarianti del paesaggio e della città, sia i testi di Francesco
Venezia, non a caso scritti al tempo presente
Fron G.I.S. to S.I.G.. From Geographical Information Systems to Systems for Geodata Interoperability.
No full text
SPANX-B and SPANX-C (Xq27 region) gene dosage analysis in Down's syndrome subjects with undescended testes
No full textDown’s syndrome (DS) is one of the most common numer-
ical chromosomal aberrations, usually caused by trisomy of
chromosome 21, and is frequently complicated with congen-
ital heart defects, duodenal obs
truction and other conditions
including undescended testis (UDT) (Fonkalsrud 1970). The
incidence of undescended testes in DS was reported to be
6.52% (Chew and Hutson 2004) while the incidence of UDT
in the first year is approximately 0.2%–0.8% in the nor-
mal population (Benson
et al
. 1991; Ichiyanagi
et al
. 1998).
Rapley
et al
. (2000) provided evidence for a testicular germ-
cell tumours (TGCT) predisposition locus at Xq27; the au-
thors obtained an hlod score of 4.7 from families with at least
one bilateral case, corresponding to a genome-wide signifi-
cance level of
P
=
0
.
034. The proportion of families with
undescended testis linked to this locus was 74%.
SPANX
(sperm protein associated with the nucleus in the X chro-
mosome) gene family maps in the same chromosomal region
and seven highly homologous genes belonging to this fam-
ily have been described (
SPANX-A1, SPANX-A2, SPANX-B1,
SPANX-B2, SPANX-C, SPANX-D
and
SPANX-E
) according
to the human genome database build 36.2. These genes,
made up of two exons separated by a small intron of
≈
650
bp, are expressed in sperm cells (Westbrook
et al
. 2000) and
in many tumours (Wang
et al
. 2003; Zendman
et al
. 2003;
Westbrook
et al
. 2004). Moreover, expression of
SPANX genes has been demonstrated in TGCT (Salemi
et al
. 2006).
The function of
SPANX
gene-encoded proteins is currently
unknown, and it is also not known if all the members or
some of them are normally expressed in the testis (West-
brook
et al
. 2000). Evidence suggests that
CTp11
,which
is 100% homologous to
SPANX-C
, is expressed in tumours
such as melanoma (Zendman
et al
. 2003), and
SPANX-B
in
myeloma and other haematological malignancies (Wang
et
al
. 2003; Zendman
et al
. 2003).
SPANX-C
mRNA was found
expressed in normal tissues and in embryonal carcinomas of
the testis (Salemi
et al
. 2006). Further, it is very di
ffi
cult to
design primers adequate for gene-specific PCR amplification
within the SPANX locus. For this reason, we decided to fo-
cus our study on
SPANX-C
and
SPANX-B
genes. The aim of
this study is to evaluate the genetic variability of
SPANX-B
and
SPANX-C
in D.UDT (Down’s syndrom patients a
ff
ected
by undescended testis) compared with D (Down’s syndrom
patients without undescended testis) and Nm (normal popu-
lation)
Status of the LIGO-AURIGA Joint Burst Analysis
No full textPeter Veitch and Jesper Munch are members of the LIGO Scientific CollaborationThe recently upgraded AURIGA detector and the LIGO observatory were simultaneously acquiring data for the first time in a 2-weeks period during the LIGO S3 run. This coincidence run motivated a collaborative effort to test search methods for gravitational wave bursts on real data. The adopted method uses broad-band cross correlation for the LIGO interferometers triggered by AURIGA events in the 850-950 Hz band. This paper describes the analysis technique and gives a status report on the search, with emphasis on the tuning procedure. Preliminary network performance and background estimates will be provided.S Poggi, F Salemi (for the AURIGA collaboration) and L Cadonati (for the LIGO Scientific collaboration
A 3D approach to investigate the burials: the virtual reconstruction of tb. 22 of necropolis of Piovego (PD)
No full textThe burials of the necropolis of Piovego (PD) have been subjected in the past years to
processual research to reconstruct the post-depositional dynamics, thus providing a two-dimensional
reconstruction of the original structure of the graves. The goal of this research is to define a new
methodology on burial 22 of the necropolis, to replicate in other archaeological contexts. This new
methodology aimed to create morphometrically accurate 3D models with a correct topological
relationship between the grave finds and between them and the burial structure. 3D models of both the
findings and structural elements of the burial were made from graphic documents with the aid of 3D
modelling and 3D scanning techniques. The use of 3D models allowed the development of new
hypotheses on the placement of the grave goods and their position within the space available in the
burial. Furthermore, the models were useful to measure more accurately the perishable elements and
to estimate their shape and position. The digital technologies allowed us to work in a threedimensional perspective, overcoming the limits of a traditional approach and verifying previous
hypotheses on the topology of the burial, such as positioning of the finds and the existence of
perishable materials that were not preserved
Methods and results of the IGEC search for burst gravitational waves in the years 1997—2000
No full textSearch fro gravitational signal from Gamma Ray Burst
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