1,128 research outputs found
Métricas de autor Alexander Cotte Poveda
No full textInforme de las métricas de autor del Dr. Alexander Cotte Poveda de las publicaciones indexadas en Google Académico cuyo objetivo es entregar un insumo para el fortalecimiento de las capacidades y potencialidades de los autores de la Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicacionesReport of the author metrics Alexander Cotte Poveda of the publications indexed in Google Scholar whose objective is to provide an input for the strengthening of the capacities and potentialities of the authors of the Santo Tomás University in the positioning and visibility of their publications.http://unidadinvestigacion.usta.edu.c
Endogenous incomplete markets, enforcement constraints, and intermediation
No full textAlvarez and Jermann (2000) show that the constrained efficient allocations of endowment economies with imperfect risk sharing due to limited commitment can be decentralized as competitive equilibria with endogenous debt constraints that are not too tight. These are the loosest possible borrowing limits that do not allow for default in equilibrium. However, such a decentralization is not possible in the presence of capital accumulation, since changes in the aggregate capital also affect the incentives to default. In a model with endogenous production, aggregate risk, and competitive intermediaries, we show that a decentralization with endogenous debt constraints is possible if one also imposes an upper limit on the intermediaries’ capital holdings.Complete markets, enforcement constraints, intermediation
Optimizing management of treatment-naïve and treatment-experienced HIV+ patients: the role of maraviroc
No full textEva Poveda, Vincent SorianoDepartment of Infectious Diseases, Hospital Carlos III, Madrid, SpainAbstract: Maraviroc is the first CCR5 antagonist approved for the treatment of HIV-1 infection. It specifically inhibits the replication of R5 viruses by blocking viral entry. HIV-1 tropism can be estimated accurately and predict viral response to maraviroc. Genotypic tools are increasingly replacing phenotypic assays in most places. The favorable pharmacokinetic properties and the good safety profile of maraviroc may support an earlier use of the drug in HIV-1 infection, as well as favor its consideration as part of switch strategies in patients under suppressive antiretroviral regimens containing less-well-tolerated drugs. Moreover, a particular immune benefit of maraviroc might encourage its use as part of intensification strategies in HIV-infected patients with impaired CD4 gains despite prolonged suppression of HIV replication with antiretroviral therapy. However, the long-term consequences of using maraviroc must be carefully checked, given its particular mechanism of action, blocking a physiologic cell receptor.Keywords: maraviroc, tropism, HIV, antiretroviral therapy, treatment strategie
Bilingual Education: English and the life projects of youth in contemporary Spain
No full textThis chapter explores the language biographies of secondary school students who attend CLIL-type programs in two regions of Spain, Catalonia and Castilla-La Mancha, in order to understand the role of English in their daily lives as well as the subjectivities that emerge in relation to their engagement with the English language. Data were collected in a multi-sited, critical sociolinguistic team ethnography and we center on group activities and group interviews with adolescents. Through an examination of students’ discourses, reported practices and life-projects connected to English we aim to give an account of the ways in which youngsters with differential access to material resources and different aspirations, navigate social relations and imagine future plans. Even though we collected complex language biographies and life projects, we will focus on two distinct discursive formations around English. Some students, who are not academically orientated, present English as a difficult school subject, which they sometimes struggle to master but still see as relevant for blue-collar and public service-oriented work projects. Middle-class and upper-middle class students describe their English language in more positive terms, seeing themselves as emergent bilinguals and connecting this identity to cosmopolitan and international professional life and work projects. Independently from their socioeconomic background and aspirations, the roles that youngsters give to English in their future lives epitomize processes of being socialized into late capitalism and neoliberalism
The relationship between development, investments, insecurity and social conditions in Colombia: a dynamic approach
No full textIn this paper, we investigate the relationship between economic development, investments, savings, insecurity and social conditions in Colombian departments. Using a dynamic heterogeneous panel analysis, we study the effects of insecurity and social conditions on economic development through an estimation of panel data cointegration techniques. The models applied in this study suggest a long-term relationship among economic development, investments, savings, social conditions and insecurity. Investments, savings and human development index have a positive and significant coefficient, which indicates that these variables produce incentives for economic development, whereas GINI and homicides have a negative relationship, demonstrating that these variables undermine economic development. All findings are important in the design of strategies and policies that strengthen income distribution equality, a key factor that determines growth and development through adequate government expenditures that encourage savings and investment decisions with the aim to improve welfare and the standard of living. © 2012 The Author(s)
Supplemental Material - Progress in the quality of care for newly diagnosed people with HIV in Spain (2004–2019)
No full textSupplemental Material for Progress in the quality of care for newly diagnosed people with HIV in Spain (2004–2019) by Belén Alejos, Cristina Díez, María J Galindo, Juan C López, Estela Moreno-García, Vicente Estrada, Eva Poveda, Mohamed Omar, Inmaculada Jarrín, Juan Berenguer, For CoRIS in Antiviral Therapy</p
Supplemental Material - Progress in the quality of care for newly diagnosed people with HIV in Spain (2004–2019)
No full textSupplemental Material for Progress in the quality of care for newly diagnosed people with HIV in Spain (2004–2019) by Belén Alejos, Cristina Díez, María J Galindo, Juan C López, Estela Moreno-García, Vicente Estrada, Eva Poveda, Mohamed Omar, Inmaculada Jarrín, Juan Berenguer, For CoRIS in Antiviral Therapy</p
Estimating Effectiveness of the Control of Violence and Socioeconomic Development in Colombia: An Application of Dynamic Data Envelopment Analysis and Data Panel Approach
No full textThis paper develops an index to evaluate the level of effectiveness of the control of violence based on the data envelopment analysis approach. The index is used to examine the grade of effectiveness of the control of violence at the level of Colombian departments between 1993 and 2007. Comparing the results across Colombian departments, we find that the majority of departments show improvement in their scores of effectiveness. A second stage of the regression model reveals that departments with a higher gross domestic product and higher education and employment are more effective in the control of violence, whereas departments with higher political violence, unemployment rates, unsatisfied basic needs, a displaced population, and hectares cultivated with coca show lower effectiveness in the control of violence. All these findings are of particular interest in the formulation and development of policies against violence, taking into account that organised forms of violence, such as drug trafficking, impede the adequate effectiveness of its control. Moreover, violence decreases social investments, generating alterations in social services that produce long-run deterioration in faith in the government\u27s ability to govern, which should become an incentive to further violence. © 2010 The Author(s)
Asset pricing with adaptive learning
No full textWe study the extent to which self-referential adaptive learning can explain stylized asset pricing facts in a general equilibrium framework. In particular, we analyze the effects of recursive least squares and constant gain algorithms in a production economy and a Lucas type endowment economy. We find that recursive least squares learning has almost no effects on asset price behavior, for either model, since the algorithm converges fast to rational expectations. At the other end, constant gain learning may sometimes contribute towards explaining the stock price volatility and the predictability of excess returns in the endowment economy. However, in the production economy the effects of constant gain learning are mitigated by the persistence induced by capital accumulation. We conclude that, contrary to popular belief, standard self-referential learning alone cannot resolve the asset pricing puzzles observed in the dataAsset pricing, adaptive learning, excess returns, predictability.
Complete Markets, Enforcement Constraints and Intermediation
No full textAlvarez and Jermann (2000) show that the constrained efficient allocations of endowment economies with complete markets and limited commitment can be decentralized with endogenous borrowing limits on the Arrow securities. In a model with capital accumulation, aggregate risk and competitive intermediaries, we show that such a decentralization is not possible unless one imposes an upper limit on the intermediaries' capital holdings. Since there is no empirical evidence of such restrictions, we also characterize the equilibrium with no capital accumulation constraints. We show that this allocation solves a similar system of equations to the one of the constrained optimal solution, a result which considerably simplifies the equilibrium computation. In addition, capital accumulation is higher in this case, since the intermediaries do not internalize that fact that a higher aggregate capital increases the incentives to default. Finally, this also implies that agents may enjoy a higher welfare in the long run in spite of the fact that this allocation is not constrained efficientComplete markets, Enforcement Constraints, Intermediation
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