1,721,476 research outputs found
A dialogue between the editor-in-chief and a deputy editor of a cardiology journal during the coronavirus outbreak: Take-home messages from the Italian experience
No full textExercise oscillatory ventilation in heart failure and brain–lung–heart–muscle crosstalk
Full text linkLetter by Aimo et al Regarding Article, "development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies"
No full textCocaine and methamphetamine use and hospitalization for acute heart failure: Epidemiological evidence from a nationwide dataset
No full textBiomarker-guided management in acute heart failure: is there light at the end of the tunnel?
No full textEvaluating biomarkers as predictors of cancer therapy cardiotoxicity: all you need is a meta-analysis?. Letter regarding the article ‘Troponins and brain natriuretic peptides for the prediction of cardiotoxicity in cancer patients: a meta-analysis.’
No full textMetabolic Surgery Saves Lives: Let Us Treat Obesity to Reduce the Perils of Obstructive Sleep Apnea
No full textTafamidis is entering the clinical arena for the treatment of transthyretin-related cardiomyopathy: certainties and unmet needs
No full textThis article refers to ‘Efficacy and safety of tafamidis doses in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT) and long-term extension study’ by T. Damy et al., published in this issue on pages 277–285
Periodic breathing during incremental exercise
No full textPeriodic breathing during incremental cardiopulmonary exercise testing is a regularly recurring waxing and waning of tidal volume due to oscillations in central respiratory drive. Periodic breathing is a sign of respiratory control system instability, which may occur at rest or during exercise. The possible mechanisms responsible for exertional periodic breathing might be related to any instability of the ventilatory regulation caused by: (1) increased circulatory delay (i.e., circulation time from the lung to the brain and chemoreceptors due to reduced cardiac index leading to delay in information transfer), (2) increase in controller gain (i.e., increased central and peripheral chemoreceptor sensitivity to arterial partial pressure of oxygen and of carbon dioxide), or (3) reduction in system damping (i.e., baroreflex impairment). Periodic breathing during exercise is observed in several cardiovascular disease populations, but it is a particularly frequent phenomenon in heart failure due to systolic dysfunction. The detection of exertional periodic breathing is linked to outcome and heralds worse prognosis in heart failure, independently of the criteria adopted for its definition. In small heart failure cohorts, exertional periodic breathing has been abolished with several dedicated interventions, but results have not yet been confirmed. Accordingly, further studies are needed to define the role of visceral feedbacks in determining periodic breathing during exercise as well as to look for specific tools for preventing/treating its occurrence in heart failure
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