106 research outputs found
Gutierrez_et_al_Supplemental_Material_revision20190224 – Supplemental material for Sleep disturbances in HIV-infected patients associated with depression and high risk of obstructive sleep apnea
No full textSupplemental material, Gutierrez_et_al_Supplemental_Material_revision20190224 for Sleep disturbances in HIV-infected patients associated with depression and high risk of obstructive sleep apnea by Jeydith Gutierrez, Ellen M Tedaldi, Carl Armon, Vaidahi Patel, Rachel Hart and Kate Buchacz in SAGE Open Medicine</p
La Chronique de Jacopo Tedaldi : le texte d’une « information » sur la chute de Constantinople
No full textL’articolo è dedicato alla cosiddetta Cronaca di Jacopo Tedaldi sulla caduta di Costantinopoli del 1453. Era già noto che quest’opera ci fosse giunta in una versione medio-francese (trasmessa da sei manoscritti) e in una latina (trasmessa da un codex unicus). Nel primo capitolo, l’autore dell’articolo esamina attentamente la tradizione manoscritta della versione medio-francese. Nel secondo, si concentra sulla versione latina. Tale analisi lo induce a concludere che quest’ultima debba derivare dall’altra versione. Nel terzo capitolo, l’autore passa in rassegna le diverse versioni medio-francesi, al fine di ricostruire dunque il testo originale. Egli sostiene che la Cronaca non debba essere attribuita a Tedaldi, ma a qualcun altro che la redasse in medio-francese, in territorio veneziano, nel corso dell’estate del 1453. Questa persona probabilmente si basò su varie fonti che giungevano dall’Oriente in quel periodo, incluso il resoconto di Tedaldi dell’assedio di Costantinopoli. Poiché i manoscritti medio-francesi non trasmettono sei versioni discordanti di un solo testo, ma sei diverse parafrasi, risulta impossibile preparare una vera e propria edizione critica. Per questo motivo, l’autore ha ritenuto opportuno fornire una ricostruzione del testo originale fondata esclusivamente sui contenuti, in lingua francese moderna (è riportata in calce all’articolo). La trascrizione di tutte le sei versioni medio-francesi si trova invece in appendice.The article deals with the so-called Jacopo Tedaldi’s Chronicle of the fall of Constantinople in 1453. It was already known that this work has come down to us in a Middle French version (transmitted by six manuscripts) and in a Latin one (transmitted by a codex unicus). In the first chapter, the author of the article thoroughly examines the manuscript tradition of the Middle French version. In the second chapter, he addresses the Latin one. This analysis allows him to conclude that the latter must derive from the former. In the third chapter, he deals with the different Middle French versions, in order to reconstruct the original text. The author argues that the Chronicle should not be ascribed to Tedaldi, but to someone else who wrote it in Middle French in the Venetian territory during the summer 1453. This person probably relied on several sources coming from the East at that time, including Tedaldi’s report of the siege of Constantinople. Since the Middle French manuscripts do not transmit six dissimilar versions of a single text, but six different paraphrases, it is not possible to prepare a real critical edition. For this reason, the author has opted for providing a reconstruction of the original text only with regard to the contents, in modern French (it is found at the end of the article). The transcription of all the six Middle French versions is provided as an appendix
THE MEANING AND UNDERSTANDING OF UNINTENDED PREGNANCY: A QUALITATIVE STUDY OF PREGNANCY AMONG AFRICAN AMERICAN WOMEN LIVING WITH HIV
No full textFew studies explore the phenomenon of unintended pregnancy among women living with the Human Immunodeficiency Virus (HIV). To decrease mother-to-child transmission and transmission to a sexual partner, contraceptive methods, cultural beliefs, in addition to protocols pertaining to preconception, pregnancy, labor, delivery and the postpartum period among persons living with HIV must be considered. Half of the pregnancies that occur among HIV-positive women are unintended and requires monitoring and additional prenatal care to reduce adverse health outcomes. This qualitative study sought to increase knowledge of the meaning and understanding of unintended pregnancy among a sample of twelve urban HIV-seropositive African American women. Women shared their experiences related to pregnancy, risk and living with HIV. The majority of participants reported they experienced an unintended pregnancy, discussed lapses in contraception use, knowledge of pregnancy and antiretrovirals, vertical transmission of the virus, sexual risk, and differences in adherence to antiretrovirals during and after pregnancy. Guided by grounded theory the major themes that emerged were used to develop a model that explained unintended pregnancy among the participants. The major themes included resilience, disclosure, and an instinct to protect. Additionally, culture, stigma, social support, contraception, and partner safety were secondary themes. Our review suggests that a model of unintended pregnancy containing social-ecological aspects can describe predictors of pregnancy and potential prevention strategies. Furthermore, the future exploration of the challenges that African American women living with HIV experience with unintended pregnancies, efforts to manage their condition and prepare for a pregnancy are needed.Public Healt
HIV-Associated Neurocognitive Disorders: The Relationship of HIV Infection with Physical and Social Comorbidities
No full textThe prevalence of HIV (human immunodeficiency virus) associated neurocognitive disorders (HAND) will undoubtedly increase with the improved longevity of HIV-infected persons. HIV infection, itself, as well as multiple physiologic and psychosocial factors can contribute to cognitive impairment and neurologic complications. These comorbidities confound the diagnosis, assessment, and interventions for neurocognitive disorders. In this review, we discuss the role of several key comorbid factors that may contribute significantly to the development and progression of HIV-related neurocognitive impairment, as well as the current status of diagnostic strategies aimed at identifying HIV-infected individuals with impaired cognition and future research priorities and challenges.Lewis Katz School of MedicineMedicineNeuroscienc
Robert, fils de Tédald, et la «Vie de saint Nicolas» de Wace
No full textRÉSUMÉ: Après avoir présenté les hypothèses antérieures relatives à l’identification de Robert le Fiz Tiout, un noble caenais du milieu du XIIe siècle et commanditaire de Wace dans la Vie de saint Nicolas, l’auteur s’intéresse à l’édition récente du cartulaire de l’abbaye Saint-Étienne de Caen. L’un des documents de ce cartulaire date du milieu du XIIe siècle et contient des références à un certain Robertus filius Tedaldi. Ce Robert serait, en toute probabilité, le commanditaire de Wace. Les détails fournis par le document invitent aussi à soupçonner les motivations du patronage littéraire de Robert: un acte de pénitence accompli sans doute vers la fin de sa vie.MOTS-CLÉS: Commanditaire – Littérature française du XIIe siècle – chartes normandes – pénitence ABSTRACT: Taking into account previous hypotheses dealing with the identification of Robert le fiz Tiout, a mid-12th century nobleman from Caen and Wace’s patron in the Vie de saint Nicolas, the author points towards the recent edition of a cartulary belonging to the abbey of Saint-Étienne in Caen. One of its mid-12th century documents contains references to a certain Robertus filius Tedaldi, Wace’s patron in all probability. The details in the document provide an explanation for the motivations of Robert’s literary patronage, most probably as a penitential act accomplished towards the end of his life.KEYWORDS: Patronage – 12th century French literature – Norman charters – Penitenc
Robert, fils de Tédald, et la « Vie de saint Nicolas » de Wace
No full textInternational audienceTaking into account previous hypotheses dealing with the identification of Robert le fiz Tiout, a mid-12th century nobleman from Caen and Wace’s patron in the Vie de saint Nicolas, the author points towards the recent edition of a cartulary belonging to the abbey of Saint-Étienne in Caen. One of its mid-12th century documents contains references to a certain Robertus filius Tedaldi, Wace’s patron in all probability. The details in the document provide an explanation for the motivations of Robert’s literary patronage, most probably as a penitential act accomplished towards the end of his life.Après avoir présenté les hypothèses antérieures relatives à l’identification de Robert le Fiz Tiout, un noble caenais du milieu du XIIe siècle et commanditaire de Wace dans la Vie de saint Nicolas, l’auteur s’intéresse à l’édition récente du cartulaire de l’abbaye Saint-Étienne de Caen. L’un des documents de ce cartulaire date du milieu du XIIe siècle et contient des références à un certain Robertus filius Tedaldi. Ce Robert serait, en toute probabilité, le commanditaire de Wace. Les détails fournis par le document invitent aussi à soupçonner les motivations du patronage littéraire de Robert: un acte de pénitence accompli sans doute vers la fin de sa vie
AIDS Res Treat
No full textBackground. It is unclear if CD4 cell counts at HIV diagnosis have improved over a 10-year period of expanded HIV testing in the USA. Methods. We studied HOPS participants diagnosed with HIV infection \ue2\u2030\ua46 months prior to entry into care during 2000-2009. We assessed the correlates of CD4 count <200 cells/mm(3) at HIV diagnosis (late HIV diagnosis) by logistic regression. Results. Of 1,203 eligible patients, 936 (78%) had a CD4 count within 3 months after HIV diagnosis. Median CD4 count at HIV diagnosis was 299 cells/mm(3) and did not significantly improve over time (P = 0.13). Comparing periods 2000-2001 versus 2008-2009, respectively, 39% and 35% of patients had a late HIV diagnosis (P = 0.34). Independent correlates of late HIV diagnosis were having an HIV risk other than being MSM, age \ue2\u2030\ua535 years at diagnosis, and being of nonwhite race/ethnicity. Conclusions. There is need for routine universal HIV testing to reduce the frequency of late HIV diagnosis and increase opportunity for patient- and potentially population-level benefits associated with early antiretroviral treatment
Prev Med
No full textBackground:Suicidal ideation (SI) refers to an individual thinking about, considering or planning suicide. Identifying and characterizing persons with HIV (PWH) at greater risk for SI may lead to better suicide prevention strategies and quality of life improvement.Methods:Using clinical data gathered from medical chart abstraction for HIV Outpatient Study (HOPS) participants from 2000 to 2017, we assessed SI frequency among PWH in care and explored factors associated with the presence of SI diagnoses using linear mixed models analyses.Results:Among 6706 participants, 224 (3.3%) had a charted diagnosis of SI. Among those with SI, median age (interquartile range [IQR]) was 43.4 years [IQR: 38.7\u201350.3], median (IQR) CD4+ cell count was 439 cells/mm3 (IQR: 237\u2013686), 71.4% were male, 54% were men who have sex with men (MSM), 25.4% heterosexual, and 13.4% persons who inject drugs. In multivariable analysis, persons at increased risk for SI were more likely to be:<50 years old (adjusted rate ratio [aRR] 1.86, 95% confidence interval [95%CI] 1.36\u20132.53), non-Hispanic/Latino black (aRR 1.75; 95%CI 1.29\u20132.38), have CD4+ cell count<350 cells/mm3 (aRR 1.32; 95%CI 1.05\u20131.65), have a viral load 6550 copies/mL (aRR 1.49; 95%CI 1.12\u20131.98), have stopped antiretroviral therapy (aRR 1.46; 95%CI 1.10\u20131.95), have a history of: alcohol dependence (aRR 2.75; 95%CI 1.67\u20134.52), and drug overdose (aRR 4.09; 95%CI 2.16\u20137.71).Conclusion:Routine mental health assessment and monitoring are needed in HIV clinical practice to better understand factors associated with SI and to inform the development of preventive interventions.CC999999/ImCDC/Intramural CDC HHSUnited States
CD163/CD16 Coexpression by Circulating Monocytes/Macrophages in HIV: Potential Biomarkers for HIV Infection and AIDS Progression
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