6,234 research outputs found
Agony in the Garden of Gethsemane
Dedicated December 13, 1959 in memory of John Frederick Dan-… and his wife M… Jackson. Matthew 26:36-46. Depicts the Garden of Gethsemane and Christ in prayer. Below are disciples and in the background those coming to arrest Christ. Singed Yvonne Williams / Ellen Simon ‘59. Williams notes that she designed the window, its colouring, and painted the glass while Ellen Simon developed the window and cartoon. Location North Nave Wall, 4th window (east to west) Lead Investigator and Photograph: C. Cody Barteet ([email protected]).https://ir.lib.uwo.ca/y_williams_stainedglass_on_toronto_stmikesangels/1016/thumbnail.jp
Les quatre Henri, ou, le jugement du meunier de Lieursain : parodie sans parodie, en un acte mêlé de vaudevilles / par M. Bernard ; représentée pour la première fois, sur le théâtre du Vaudeville, le 2 août 1806.
M. Bernard is a collective pseudonym for Michel Dieulafoy and Gersin--Cf. Quèrard, Supercheries, vol. 1, col. 545. Variously attributed to H. Simon as a further joint author. Without music; tunes indicated by title
Depression in general practice : underrecognition? Overtreatment? Adequate care!
Dit proefschrift geeft een optimistisch beeld van de huidige zorg voor depressieve patiënten in de huisartsenpraktijk i.v.m. eerdere literatuur en mediaberichten. We concluderen dat, de zorg voor depressieve patiënten in de eerste lijn in het algemeen adequaat is, d.w.z. in overeenstemming met aanbevelingen uit geldende richtlijnen.
Ruim twee-derde van de depressieve patiënten werd door de huisarts herkend. Patiënten die psychische problemen met de huisarts bespraken, met meer depressieve symptomen en met tevens een angststoornis werden beter herkend. Het atypische symptoom toegenomen eetlust leidde tot slechtere herkenning.
58% van de depressieve patiënten werd verwezen voor psychologische of psychiatrische zorg. Huisartsen hielden de aanbevelingen voor verwijzing uit de richtlijn hierbij in het oog, patiënten met voorkeur voor psychotherapie, met chronische depressie of suïcidale neigingen werden vaker verwezen.
Ook behandeling met antidepressiva schrijven huisartsen volgens de richtlijn voor. Slechts bij 5,4% van de antidepressiva-gebruikers was sprake van overbehandeling. Bovendien was meer dan de helft van deze overbehandelde patiënten met een goede reden gestart, maar te lang doorbehandeld.
Uit een literatuur-review concludeerden wij dat aanbevelingen voor antidepressiva-gebruik gebaseerd zijn op voldoende bewijs v.w.b. acute behandeling en preventie van terugval gedurende enkele maanden, maar niet voor langdurige onderhoudsbehandeling.
Aanbevelingen voor onderhoudsbehandeling worden ook minder goed gevolgd. Het zijn niet, zoals de richtlijn voorschrijft, patiënten met een chronische of recidiverende depressie die onderhoudsbehandeling krijgen. Wel lijken het patiënten met een slechtere prognose: patiënten met tevens een angststoornis of dysthyme stoornis (langdurige ‘milde’ depressie), patiënten die naast antidepressiva ook kalmerende middelen gebruikten en met recente psychiatrische contacten.
Overall this thesis gives an optimistic picture of current care for depressed patients in primary care compared to previous literature and media reports. We conclude that, in general, the care for depressed patients in primary care is in most cases adequate, i.e. in accordance with ruling guideline recommendations.
The general practitioner recognized over two-thirds of depressed patients. Patients discussing psychological problems with the general practitioner, those with more depressive symptoms and with a concurrent anxiety disorder were better recognized. The atypical symptom increased appetite led to worse recognition.
58% of depressed patients were referred for psychological or psychiatric care. General practitioners took guideline recommendations into account in referring; patients with preference for psychotherapy, chronic depression or suicidal tendency were referred more often.
Treatment with antidepressants was also prescribed according to guideline recommendations. In only 5.4% of antidepressant users it could be called overtreatment. Furthermore, over half of these overtreated patients started with a good reason, but were treated too long according to guideline recommendations.
From review of the literature we conclude that guideline recommendations for antidepressant treatment are thoroughly evidence-based for acute treatment and relapse prevention during several months, but not for maintenance treatment.
Recommendations for maintenance treatment are also less often followed. Maintenance users are not, as the guideline prescribes, patients with chronic or recurrent depression. It does however seem that maintenance antidepressant users are those with a worse prognosis such as patients with comorbid dysthymia or anxiety and patients also receiving sedatives or patients with recent psychiatric contacts.
Photosymbiont associations persisted in planktic foraminifera during early Eocene hyperthermals at Shatsky Rise (Pacific Ocean)
Understanding the sensitivity of species-level responses to long-term warming will become increasingly important as we look towards a warmer future. Here, we examine photosymbiont associations in planktic foraminifera at Shatsky Rise (ODP Site 1209, Pacific Ocean) across periods of global warming of differing magnitude and duration. We compare published data from the Paleocene-Eocene Thermal Maximum (PETM; ~55.9 Ma) with data from the less intense Eocene Thermal Maximum 2 (ETM2; ~54.0 Ma), and H2 events (~53.9 Ma). We use a positive relationship between test size and carbon isotope value (size-δ13C) in foraminifera shells as a proxy for photosymbiosis in Morozovella subbotinae and Acarinina soldadoensis, and find no change in photosymbiont associations during the less intense warming events, in contrast with PETM records indicating a shift in symbiosis in A. soldadoensis (but not M. subbotinae). Declines in abundance and differing preservation potential of the asymbiotic species Subbotina roesnaesensis along with sediment mixing likely account for diminished differences in δ13C between symbiotic and asymbiotic species from the PETM and ETM2. We therefore conclude that photosymbiont associations were maintained in both A. soldadoensis and M. subbotinae across ETM2 and H2. Our findings support one or both of the hypotheses that 1) changing symbiotic associations in response to warming during the PETM allowed A. soldadoensis and perhaps other acarininids to thrive through subsequent hyperthermals or 2) some critical environmental threshold value was not reached in these less intense hyperthermals.ET recognizes funding by National Science Foundation (NSF) OCE 1536611. PMH, SD, and JOS recognize funding by NSF OCE 1536604 and a Sloan Research Fellowship
Smart Energy Research Lab Observatory Data, 2019-2021: Secure Access (Edition 4)
The vision of the Smart Energy Research Lab (SERL) is to deliver a unique data resource harnessing the benefits of smart meter data for research. The portal will transform Great Britain's energy research through the long-term provision of high quality, high-resolution energy data that will support the development of a reliable evidence base for intervention, observational and longitudinal studies across the socio-technical spectrum.
The goals of the Smart Energy Research Lab are to provide:
A trusted data resource for researchers to utilise large-scale, high-resolution energy data
An effective mechanism for collecting and linking energy data with other contextual data
High quality data management to ensure fit-for-purpose data are provisioned to researchers
Participant recruitment began in August 2019. Approximately 1,700 participants were recruited from central and southern England and from Wales as part of a pilot study that tested different recruitment strategies. The second recruitment wave took place in August-September 2020, and the third wave at the start of 2021. SERL aims to recruit around 10,000 households to be regionally representative across England, Scotland and Wales. Recruitment is also designed to be representative of each Index of Multiple Deprivation (IMD) quintile; an area-based relative measure of deprivation.
For the latest (4th) edition (October 2021) all SERL data up to and including 31 May 2021, which includes participant households recruited in Waves 1, 2 and 3, were made available.</span
Petr Simon (1944-2018)
This article is a reflection on the mathematical legacy of Professor Petr Simon.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Analysi
A Comparative Study of the TEA, XTEA, PRESENT and Simon lightweight cryptographic schemes
With the current fast paced growth in the number of devices connected to the internet, many of these having limited computational capability, security concerns are of increasing importance. To meet the necessity of providing secure encryption to constrained devices many lightweight cryptographic schemes have been developed. This paper provides a comparative study of four of these schemes, namely TEA, XTEA, PRESENT and Simon, explaining how they work and discussing their vulnerabilities and performances. This paper specifically considers the performance of Application Specific Integrated Circuit (ASIC) implementations with regards to their size, throughput, power usage and energy usage per bit encrypted. TEA and PRESENT were found to have potentially problematic vulnerabilities, while no attacks on XTEA and Simon are known that do not reduce the number of rounds used during encryption. Simon and PRESENT were found to perform well, while XTEA implementations were found to be too large for constrained devices. Out of the four, Simon seems the most promising for use in constrained devices. As such, further research into its vulnerabilities is advisable.CSE3000 Research ProjectComputer Science and Engineerin
The long-wavelength view of GG Tau A: rocks in the ring world
We present the first detection of GG Tau A at centimetre wavelengths, made with the Arcminute Microkelvin Imager Large Array at a frequency of 16 GHz (λ = 1.8 cm). The source is detected at >6 σrms with an integrated flux density of S16GHz = 249 ± 45 µJy. We use these new centimetre-wave data, in conjunction with additional measurements compiled from the literature, to investigate the long-wavelength tail of the dust emission from this unusual protoplanetary system. We use an MCMC-based method to determine maximum likelihood parameters for a simple parametric spectral model and consider the opacity and mass of the dust contributing to the microwave emission. We derive a dust mass of Md ~ 0.1 Msun, constrain the dimensions of the emitting region and find that the opacity index at λ > 7 mm is less than unity, implying a contribution to the dust population from grains exceeding ~4 cm in size. We suggest that this indicates coagulation within the GG Tau A system has proceeded to the point where dust grains have grown to the size of small rocks with dimensions of a few centimetres. Considering the relatively young age of the GG Tau association in combination with the low derived disc mass, we suggest that this system may provide a useful test case for rapid core accretion planet formation models
Łojasiewicz–Simon gradient inequalities for coupled Yang–Mills energy functions
We prove Lojasiewicz–Simon gradient inequalities for coupled Yang–Mills energy functions using Sobolev spaces which impose minimal regularity requirements on pairs of connections and sections. The Lojasiewicz–Simon gradient inequalities for coupled Yang–Mills energy functions generalize that of the pure Yang–Mills energy function due to the first author (Feehan, 2014) for base manifolds of arbitrary dimension and due to R˚ade (1992, Proposition 7.2) for dimensions two and three
The feasibility of csem monitoring in gas hydrate production of the range of porosity and saturation
Natural gas hydrates production tests over the last two decades has sown that production is not without risks. Indirect effects in the sedimentary rocks of phase changes are changes in porosity, permeability, and saturation. From a field production test site, porosity changes in the range of 15% to 19% and saturation from 5% to 60% were reported. Monitoring is in principle possible using an electromagnetic survey with a downhole vertical electric source and a horizontal electric field receiver on the seafloor. Computed model responses over a wide frequency range and for many depth locations of an electric current source show that both changes can be detected. Best detectability occurs when the current source is below the reservoir layer in case of changes differences can be detected above, inside and below the reservoir layer at frequencyies below 10 Hz. At a source operating frequency of 0.1 Hz maximum response difference between the two values in saturation occur when the source is 20 m above the top of the reservoir layer unil 100 m below the bottom. Only below the top of the reservoir there is almost no difference in the electric field amplitude between the two saturation levels below 10 Hz.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Applied Geophysics and Petrophysic
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