16 research outputs found
Epicardial, Biatrial Ablation With Integrated Uni-bipolar Radiofrequency Technology in Stand-alone Persistent Atrial Fibrillation
No full textAlthough minimally invasive approaches for surgical treatment of stand-alone atrial fibrillation have gained popularity for the past decade, ablation technology and extensive lesion sets play a major role in the achievement of a successful procedure, especially in presence of persistent and long-standing persistent atrial fibrillation. We evaluated clinical outcomes after totally endoscopic biatrial epicardial ablation of persistent atrial fibrillation with a novel integrated uni-bipolar radiofrequency device
Determinants of pericardial drainage for cardiac tamponade following cardiac surgery
No full textObjective: We aimed to identify independent risk factors predisposing toward postoperative surgical or percutaneous pericardial drainage following cardiac surgery, and to assess late survival. Methods: A retrospective review of preoperative, intra-operative and postoperative variables was conducted in 5818 patients, who underwent adult heart surgery in a 7-year time span (2002-2009). Pericardial drainage was performed in 117 patients (2%), of whom 52 (44%) were evacuated by surgical drainage and 65 (56%) by echocardiographic-guided pericardiocentesis. Patients were divided in two groups: patients with two-dimensional (2D) echocardiographic evidence of cardiac tamponade, who underwent pericardial surgical or percutaneous drainage (group I: 117 patients); and patients without cardiac tamponade (group II: 5701 patients), who served as the control group. Results: The two groups were compared with univariate analysis, and variables significantly (p≤ 0.05) or possibly (p≤ 0.2) associated with pericardial drainage were entered into multivariable logistic regression analysis models assessing the role of pre-, intra- and postoperative variables together or separately. Pericardial drainage was more likely to occur in patients undergoing combined procedures such as double/triple valves or surgery on ascending aorta, in patients with higher EuroSCORE (European System for Cardiac Operative Risk Evaluation) levels, whereas patients receiving aspirin treatment before surgery had a lower risk of this complication. In addition, postoperative blood product transfusion and the occurrence of renal failure after surgery increased the risk of this complication. Conclusions: Postoperative pericardial drainage is an uncommon complication after heart surgery, mainly managed percutaneously. Our study has identified different independent causative factors for cardiac tamponade requiring pericardiocentesis. The identification of preoperative and postoperative risk factors may be useful to adopt strategies to further reduce the incidence of pericardial tamponade requiring drainage
Acute effects of static stretching on squat jump performance at different knee starting angles
No full textThe purpose of this study was to examine the effects of static stretching on leg extensor muscles during squat jump (SJ) at different knee starting angles. Seventeen male subjects (23 ± 3 years, 179 ± 5 cm, and 74 ± 6 kg) performed on a force platform 2 series (preceded or not [control condition] by 10-minute static stretching of quadriceps and triceps surae muscles) of SJs at different knee starting angles: 50°, 70°, 90°, and 110°. Squat jump height, peak force, maximal acceleration, velocity, and power were calculated for each jump. The angle that maximized power development was obtained from the power-angle relationship. The SJ height, peak force, and maximal velocity increased according to angle amplitude in both control and stretching conditions (p < 0.01), performance being significantly lower in the stretching condition (p < 0.01). Peak power was obtained at 90° in both control and stretching conditions, but was significantly lower (p < 0.01) after stretching. These results suggest that an acute bout of static stretching reduces power and force development during SJ, decrements being significantly higher at lower knee starting angles. Therefore, the use of static stretching may be questionable in those power activities requiring maximal power output at knee angles near full extension
Gervasoni et al_2022_FR_Immunol_Suppl-DATA.txt
No full textAdditional data for the Paper: ACUTE THERMOREGULATORY AND CARDIOVASCULAR RESPONSE TO SUBMAXIMAL EXERCISE IN PEOPLE WITH MULTIPLE SCLEROSIS, by Elisa Gervasoni et al.
The data shows heart rate and core body temperatures, measured every 20 s during a 6MWT and the subsequent recovery period of 240 s. Each row contains the individual data relating to a PwMS or a control subject.</p
I reggitori di Novara, memorie / di Giuseppe Garone.
No full textFrom the library of Conte Antonio Cavagna Sangiuliani di Gualdana."Correzioni," p. 276.Includes transcriptions of documents, with listings up to 1865.Seal of the author on verso of t.p. as proof of legitimate edition.Includes bibliographical references.I duchi -- I conti -- I messi regii ed imperiali -- I vescovi- signori -- I consoli e podestà -- Consoli -- Podestà ed altri primati.Mode of access: Internet
Evaluation of the relationship between some blood metabolites and elements on the ovarian persistent follicle formation in dairy cattle
No full textThe object of this study was to investigate the effect of some blood metabolites and elements on the ovarian persistent follicle formation in dairy cattle. Blood samples were obtained from 117 lactating cows in two groups of normal and persistent follicle status. Glucose, urea, total protein, phosphorus and betahydroxy butyrate were measured by spectrophotometer method. Estradiol concentration in blood serum was measured by ELISA method. Effects of calving season, parity and milk production at 50-60 days postpartum were studied on persistent follicle status. Status of animal (presence or absence of resistant follicle) had significant effect on urea, protein, beta-hydroxybutyrate, phosphorus and estradiol (
A 12-week program of moderate intensity exercise reduces plasma myostatin in HIV-infected subjects
No full textIntroduction. We have previously observed that brisk walking, as moderate intensity physical activity, improves bone density in HIV-infected patients treated with cART, as assessed by Dual X-Ray Absorptiometry (DEXA). Aim of this study was to investigate the possible mechanisms underlying this observation and in particular whether muscle stimulation by exercise is
associated with a reduced production of myostatin (growth/differentiation factor 8, GDF-8), a negative regulator of muscle growth and osteogenesis.
Methods. We analyzed data from 25 subjects, representing a subset of a larger group of HIV-infected, cART-treated, sedentary subjects who were enrolled in a 12-week exercise program. This consisted of 3 outdoor sessions/week of 60 min walking at 65-75% of HR (Heart Rate) max with ("walk/strength" group) or without ("walk" group) 30 min circuit training at 65% of 1-RM (Repetition Maximum). Subjects were examined at baseline (BL) and 12 weeks (W12) by 6-minute walking test (6MWT) and 1-RM test. Myostatin level in plasma was determined by ELISA. Differences between BL and W12 were tested by Wilcoxon-signed paired rank test. Spearman test was used to assess correlations between variables.
Results. All participants completed the 12-week program with a median adherence of 64% (IQR 59-75). They were 20M, 5F; median 51 y-o, IQR 47-55. Fifteen subjects were enrolled in the "walk” group and 10 in the "walk/strength" group. At W12, there was a significant improvement of distance by 6MWT (p<0.0001), and of performance in all strength exercises (crunch p= 0.004, lat machine p= 0.002, chest press p= 0.002, leg extension p= 0.004, sitting calf p= 0.006, leg press p= 0.004). Plasma myostatin levels decreased significantly from a BL median value of 20.9 ng/mL (IQR 10.5-27.3) to 13.5 ng/mL (5.1-24.4) at W12 (p=0.006). A larger reduction of myostatin correlated with higher total distance walked during the 12 weeks of the training period (p=0.023) and the distance walked at W12 6MWT (p=0.008).
Conclusions. A 12-week program of moderate intensity physical exercise was associated with a reduction of plasma myostatin level. We propose a model by which exercise may induce attenuation of myostatin expression from skeletal muscle and, possibly, lead to increased bone density through reduction of its anti-osteogenic potential
Acute Thermoregulatory and Cardiovascular Response to Submaximal Exercise in People With Multiple Sclerosis
No full textBACKGROUND: Heat sensitivity occurs in a high percentage of people with multiple sclerosis (PwMS), in response to environmental or exercise-induced increase in body temperature. However, the kinetic and magnitude of adaptation of the internal load and of the core body temperature (CBT) to a submaximal continuous exercise has been poorly addressed in PwMS; this may be relevant for the brief exercise bouts usually occurring in normal daily life. The aim of this work was to evaluate whether multiple sclerosis influences the acute adaptation of the internal load, the CBT and the perceptual load in response to a constant submaximal work step. METHODS: CBT has been continuously monitored (0.5 Hz) by a validated wearable heat-flux sensor and electrocardiography was recorded (250 Hz) by a wearable device during a standard 6-minute walk test (6MWT) in 14 PwMS (EDSS, 4.7 ± 1.2; disease duration: 13.0 ± 10.2 years; m ± SD) and 14 age, sex and BMI-matched healthy subjects (HS). The rate of perceived exertion (RPE) of the lower limbs was assessed during the 6MWT by the Borg scale (6-20). RESULTS: As expected, PwMS walked a significantly shorter distance (361 ± 98 m) than the HS group (613 ± 62 m, p<0.001 vs PwMS). However, the kinetics of adaptation of CBT and the magnitude of CBT change from baseline did not differ between groups. Similarly, heart rate (HR) kinetics and HR change from baseline were comparable between groups during the 6MWT. Finally, lower limbs RPE gradually increased during the exercise test, but without significant differences between groups. CONCLUSION: The internal load, the metabolic heat production, and the perceptive load due to a standard submaximal walking exercise seems to be preserved in PwMS, suggesting a comparable acute heat production and dissipation during exercise. Therefore, it is unlikely that the different distance achieved during the 6MWT may be caused by altered thermoregulatory responses to exercise. Rather, this appears to be a consequence of the known increased energy cost of locomotion in PwMS
