1,168 research outputs found

    Multidisciplinary “Boot Camp” Training in Cellular Bioengineering to Accelerate Research Immersion for REU Participants

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    Research Experiences for Undergraduates (REU) sites widely serve as the first major research gateway for undergraduates seeking a structured research experience. Given their lack of prior research skills, and the highly compressed duration of the REU programs, these students frequently encounter barriers to a seamless transition into a new laboratory environment. We hypothesized that the design of a unified short course on laboratory and analysis techniques could serve as a pivotal orientation experience. Our goal was to rapidly align student expertise to their summer research goals while also integrating the student participants into a cohesive learning community. This article discusses the design and outcomes of a Cellular Bioengineering Boot Camp, which is offered at the outset of the 10-week REU site at Rutgers. The Boot Camp provides hands-on, supervised training for techniques and procedures that are common among projects. The training establishes a common language and baseline for the REU students and allows their first laboratory experiences to be with each other, and creates an immediate network of peers and mentors. Surveys before and after the Boot Camp and at the end of the summer indicated a significant improvement in student proficiency in the techniques that was retained throughout the summer. We believe that the Boot Camp approach can be tailored to the specifics of each REU site and its associated projects and research foci.Peer reviewe

    What works! : the working women count honor roll report : a selection of programs and policies that make work better.

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    "Author, Roberta M. Spalter-Roth"--P. iii.Includes bibliographical references.Mode of access: Internet

    Targeting tumor metastases: drug delivery mechanisms and technologies

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    Primary sites of tumor are the focal triggers of cancers, yet it is the subsequent metastasis events that cause the majority of the morbidity and mortality. Metastatic tumor cells exhibit a phenotype that differs from that of the parent cells, as they represent a resistant, invasive subpopulation of the original tumor, may have acquired additional genetic or epigenetic alterations under exposure to prior chemotherapeutic or radiotherapeutic treatments, and reside in a microenvironment differing from that of its origin. This combination of resistant phenotype and distal location make tracking and treating metastases particularly challenging. In this review, we highlight some of the unique biological traits of metastasis, which in turn, inspire emerging strategies for targeted imaging of metastasized tumors and metastasis-directed delivery of therapeutics.Peer reviewe

    A highly bioavailable omega-3 free fatty acid formulation improves the cardiovascular risk profile in high-risk, statin-treated patients with residual hypertriglyceridemia (the ESPRIT trial)

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    Abstract not availableKevin C. Maki, David G. Orloff, Stephen J. Nicholls, Richard L. Dunbar, Eli M. Roth, Danielle Curcio, Judith Johnson, Douglas Kling, and Michael H. Davidso

    Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation

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    The desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters

    Revision and Repetition : Uncovering the Feminine Aesthetic in the Work of Gerlind Reinshagen and Friederike Roth

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    ii, 414 p.The author presents original translations of two 20th Century German plays, "Die Clownin: ein Spiel" ("The Clown") by Gerlind Reinshagen and "Das Ganze ein Stuck" ("The Whole a Piece") by Friederike Roth. She includes biographical information, analysis of "Das Ganze ein Stuck," and notes on the translation process and the production of "The Clown.

    The long-wavelength view of GG Tau A: rocks in the ring world

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    We present the first detection of GG Tau A at centimetre wavelengths, made with the Arcminute Microkelvin Imager Large Array at a frequency of 16 GHz (λ = 1.8 cm). The source is detected at >6 σrms with an integrated flux density of S16GHz = 249 ± 45 µJy. We use these new centimetre-wave data, in conjunction with additional measurements compiled from the literature, to investigate the long-wavelength tail of the dust emission from this unusual protoplanetary system. We use an MCMC-based method to determine maximum likelihood parameters for a simple parametric spectral model and consider the opacity and mass of the dust contributing to the microwave emission. We derive a dust mass of Md ~ 0.1 Msun, constrain the dimensions of the emitting region and find that the opacity index at λ > 7 mm is less than unity, implying a contribution to the dust population from grains exceeding ~4 cm in size. We suggest that this indicates coagulation within the GG Tau A system has proceeded to the point where dust grains have grown to the size of small rocks with dimensions of a few centimetres. Considering the relatively young age of the GG Tau association in combination with the low derived disc mass, we suggest that this system may provide a useful test case for rapid core accretion planet formation models

    Full aperture backscatter diagnostics for characterization of laser plasma instabilities at the extreme light infrastructure (ELI) beamlines

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    We report on the commissioning of a full aperture backscatter diagnostics station for the kilojoule, nanosecond high repetition rate L4n laser operating at a wavelength of 527 nm at the Extreme Light Infrastructure (ELI) - Beamlines, Dolni Brezany, Czech Republic. Light scattered back from laser–plasma interaction into the cone of the final focusing lens is captured and split into different channels to measure the signatures of laser plasma instabilities from stimulated Brillouin scattering, stimulated Raman scattering, and two plasmon decay with respect to back scattered energy, its spectrum, and its temporal profile. The performance was confirmed in a commissioning experiment with more than 800 shots at laser intensities ranging from 0.5 × 1013 to 1.1 × 1015 W cm−2. These diagnostics are permanently installed at ELI Beamlines, and can be used to understand the details of laser–plasma interactions in experiments with kJ and 527 nm light. The large number of shots that can be collected in an experimental campaign will allow us to study the details of the laser–plasma interaction with a high level of confidence

    Violence In Divergent Novel By Veronica Roth (2011): Feminist Approach

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    This study aims to find and explain the types of violence that exist in the novel and reveal how Tris won to turn the world into peace without a faction. This research is a qualitative research. The object of this study was to analyze a novel entitled Divergent written by Veronica Roth in 2011. Data sources were analyzed through sentences related to violence found in the novel. This type of research data using text taken from two sources, namely primary data and secondary data. The author reads the novel carefully and repeatedly through primary data taken from the Divergent novel written by Veronica Roth in 2011. Then secondary data is taken through articles, internet journals related to research, literary books, and literature. The results of this study are two points. First, there are three types of violence in the novel, namely the theory of violence as an actor based on individual or group actions, the theory of structural violence, the theory of violence as a link between actors and structures. Both Tris are able to fight the violence in its path and make Tris survive to win and make the world peaceful

    On single-crystal total scattering data reduction and correction protocols for analysis in direct space. Corrigendum

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    The name of the third author of the article by Koch et al. [Acta Cryst. (2021).A77, 611–636] is corrected.The name of the third author in the article by Koch et al.(2021) is incorrectly given as Yiu Liu. The correct name is YuLiu, as given above.ReferencesKoch, R. J., Roth, N., Liu, Y., Ivashko, O., Dippel, A.-C., Petrovic, C.,Iversen, B. B., v. Zimmermann, M. & Bozin, E. S. (2021). Acta Cryst.A77, 611–636
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