6 research outputs found
Paternal age and perinatal outcomes: an observational study
No full textObjectives: The study's primary aim was to examine the relationship between paternal age and perinatal outcomes. Methods: This study used data from two hospital birth registries to examine the association between paternal age and adverse perinatal outcomes. The sample included all live singleton births between 2010 and 2022. The primary exposure was paternal age, and the following perinatal outcomes were considered: mode of conception, mode of delivery, pregnancy complications, and neonatal outcomes. Results: A total of 15,232 pregnant women were considered. Maternal and paternal ages were 31.9 ± 5.3 and 36.5 ± 6.5 years, respectively. Independent of maternal, paternal age was associated with lower odds of spontaneous conceptions (OR 0.930, 95 % CI 0.968/0.993; p=0.003) and higher odds of intracytoplasmatic sperm injection (OR 1.054, 95 % CI 1.045/1.062; p=0.0001), respectively. In contrast to maternal age, paternal age decreased the odds of any (OR 0.922, 95 % CI 0.985/0.999; p=0.032) and urgent/emergent (OR 0.984, 95 % CI 0.975/0.993; p=0.0001) cesarean delivery. Paternal age did not affect the gestation length, placental or neonatal weight, blood loss during delivery, and neonatal 5th-minute Apgar score. Conclusions: Paternal age is associated with perinatal outcomes. These findings suggest that advanced paternal age may have implications for reproductive counseling and prenatal care
Corrigendum: The new Italian registry of infantile thrombosis (RITI): a reflection on its journey, challenges and pitfalls
No full textIn the published article, there was an error in the appendix. An author name was incorrectly written as Foidaelli Thomas. The correct spelling is Foiadelli Thomas. The correct appendix appears below. – Accorsi Patrizia – Aceto Gabriella – Agnoletti Gabriella – Agostini Manuela – Alfarano Angela – Altieri Elena – Amador Carolina – Antonelli Camilla – Arena Vittoria – Asta Francesca – Baggio Laura – Ballardini Elisa – Baracetti Margherita – Baraldi Eugenio – Barberis Laura – Barisone Elena – Basso Anne Letizia – Battajon Nadia – Bersani Iliana – Biddeci Giada – Biffanti Roberta – Bonardi Claudia Maria – Bonaudo Roberto – Boniver Clementina – Boscarol Gianluca – Bottino Roberto – Bravar Giulia – Brizzi Ilaria – Brolatti Noemi – Braguglia Annabella – Guaragni Brunetta – Bugin Samuela – Calvo Pier Luigi – Capasso Antonella – Capodiferro Donatella – Cappelleri Alessia – Cascarano Maria Teresa – Casellato Susanna – Casini Tommaso – Catarzi Serena – Cavaliere Elena – Cavicchiolo Maria Elena – Celestino Silvia – Celle Maria Elena – Centonze Nicola – Cerutti Alessia – Chakrokh Roksana – Offer Chiara – Chiodin Elisabetta – Chirico Gaetano – Chukhlantseva Natalia – Cifarelli Paola – Cinelli Giulia – Coinu Marisa – Colonna Clara – Comito Donatella – Corato Alessandra – Cordelli Duccio Maria – Crichiutti Giovanni – Cursio Ida – Dagri Arianna – De Maria Beatrice – Del Borrello Giovanni – Di Rienzo Francesca – Doglioni Nicoletta – Dolcemascolo Valentina – Dotta Andrea – Drigo Paola – Drimaco Pietro – Ellero Serena – Falcone Alessandra – Fantauzzi Ambra – Farinasso Daniela – Ferilli Michela – Festa Silvia – Fischer Maximilian – Foiadelli Thomas – Fotzi Ilaria – Francavilla Rosa – Freschi Paola – Gaffuri Marcella – Gallo Elena – Gamalero Lisa – Gandioli Claudia – Garuccio Sergio – Gentile Diletta – Ghionzoli Marco – Giliberti Paola – Greco Filippo – Guariento Chiara – Guidotti Isotta – Iodice Alessandro – Janes Augusta – Laghi Elena – Lampugnani Elisabetta – Lassandro Giuseppe – Laverda Anna Maria – Lazzerotti Alessandra – Lo Tartaro Meragliotta Patrizia – Lombardini Martina – Lorenzon Eleonora – Mainini Nicoletta – Massoud Michela – Materia Valeria – Mattera Raffaele – Mauro Isabella – Melani Federico – Meli Mariaclaudia – Messina Giovanni – Monticone Sonia – Moras Marzia – Negro Ilaria – Olzai Giorgio – Pancani Simone – Pandolfi Maria – Passariello Annalisa – Passarini Alice – Passone Eva – Pastorino Myriam – Pegoraro Veronica – Pennoni Serena – Perilongo Giorgio – Pozzessere Anna – Pruna Dario – Pusiol Anna – Putti Maria Caterina – Rabbone Ivana – Radicioni Maurizio – Renna Salvatore – Ricci Maria Luisa – Rimini Alessandro – Rivellini Sara – Rustioni Gianluca – Salvadori Sabrina – Santoiemma Valentina – Santoro Nicola – Schiavulli Michele – Sebellin Sofia – Sesta Michela – Soffiati Massimo – Sorbo Monica – Spanedda Giuseppina – Stangalini Valeria – Stasolla Salvatore – Tanzi Giorgia – Testa Tiziana – Teutonico Federica – Timpani Giuseppina – Toldo Irene – Trapani Sandra – Vaccari Roberto – Vecchi Marilena – Vento Giovanni – Veraldi Daniele – Villa Giovanna – Visintin Gianluca – Zambelloni Cesare – Zellini Francesco – ASST Spedali Civili of Brescia, Brescia – Azienda Ospedaliera Bianchi-Melacrino-Morelli di Reggio Calabria, Reggio Calabria – Azienda Ospedaliera Policlinico Di Bari, Bari – Bambin Gesù Children’s Hospital, Roma – Central Teaching Hospital of Bolzano, Bolzano – Giannina Gaslini Hospital, Genova – Niguarda Hospital, Milano – Ospedale Civile SS. Annunziata, Sassari – San Bortolo Hospital, Vicenza – San Matteo Hospital, Pavia – Santa Chiara Hospital, Trento – ULSS 2 Marca Trevigiana, Treviso – ULSS 8 Berica, Vicenza – University Hospital “Azienda Ospedaliero-Universitaria Meyer”, Firenze – University Hospital Città della Salute e della Scienza, Torino – University Hospital of Modena, Modena – University Hospital of Padova, Padova – University Hospital of Udine, Udine – University Hospital of Verona, Verona – University of Bari, Bari – University of Bologna, Bologna – University of Cagliari, Cagliari – University of Catania, Catania – University of Ferrara, Ferrara – University of Napoli “Federico II”, Napoli – University of Perugia, Perugia The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated
Correction to: Safety and efficacy of COVID-19 vaccines in patients on dialysis: a multicentre cohort study in Italy
No full textThe COVIDVaxDia Study Group in html which currently reads Francesca Menniti-Ippolito, Roberto Da Cas, Flavia Chiarotti, Massimo Fabiani, Giuseppe Traversa, Piergiorgio Messa, Alfonso Mele, Salvatore De Masi, Francesca Colavita, Concetta Castilletti, Carmine Zoccali, Aldo Pietro Maggioni, Andrea Lorimer, Martina Ceseri, Ester Baldini, Francesca Bianchini, Laura Sarti, Giovanni Baglio, Andrea Mariano and Eva Alessi. It should read as: Francesca Menniti-Ippolito, Roberto Da Cas, Flavia Chiarotti, Massimo Fabiani, Giuseppe Traversa, Piergiorgio Messa, Alfonso Mele, Salvatore De Masi, Francesca Colavita, Concetta Castilletti, Carmine Zoccali, Aldo Pietro Maggioni, Andrea Lorimer, Martina Ceseri, Ester Baldini, Francesca Bianchini, Laura Sarti, Giovanni Baglio, Andrea Mariano & Eva Alessi, Lorenzo Di Liberato, Luigi Amoroso, Nicola Spetrino, Milva Di Giovanni, Carlo Sapio, Irma Figlia, Roberto Pititto, Teresa Papalia, Rosita Greco, Francesca Leone, Francesco Maria D’Agostino, Mariangela Campolo, Maria Rosa La Gamba, Francesca Mallamaci, Vincenzo Panuccio, Giovanna Parlongo, Giuseppe Natale, Domenico Tramontana, Ivania Maria Figliano, Santo Vitiello, Anna Maria Frangiosa, Domenico Caserta, Pasqualina Acconcia, Nunzia Paudice, Alfonso De Maio, Salvatore Cascone, Marilina Siani, Mario Cioffi, Nataliya Romanyuk, Franca Pagnano, Antonio De Donato, Ersilia Satta, Alessandra Perna, Francesco Trepiccione, Alessandro Cerrone, Gianluca Garofalo, Giancarlo Marinelli, Roberta D’Amato, Enrico De Felice, Alfredo Vacca, Salvatore Coppola, Vincenzo Cuomo, Maria Palma Iavarone, Annalisa Ciotola, Vincenzo Puglia, Pio Granato, Carla Lamberti, Giorgio Capasso, Domenico Bonanno, Marco Ventre, Veronica Amendola, Fabio Cappabianca, Elena Mancini, Davide Ricci, Daniela Cecilia Cannarile, Roberta Benevento, Bianca Perciaccante, Alda Storari, Yuri Battaglia, Giovanni Piva, Giovanni Mosconi, Alessandra Spazzoli, Paolo Ferdinando Bruno, Katia Ambri, Barbara Veterani, Sara Signorotti, Marcora Mandreoli, Renato Mario Rapanà, Maria Teresa Benedetto, Laura Patregnani, Maddalena Zambelli, Gaetano Alfano, Mariacristina Gregorini, Silvia Mattei, Francesca Iannuzzella, Elena Pelizzaro, Luca Camparini, Giuseppe Battaglino, Dino Romanini, Antonio Irlando, Lojze Celik, Giuseppa Natale, Maria Cristina Torre, Ilaria Umbro, Nicola Pirozzi, Loredana Fazzari, Lucia Pantano, Antonio Paone, Marco Galliani, Veronica Baglio, Eleonora Moscaritolo, Sabrina Fierimonte, Maria De Cristofaro, Elena Nebuloso, Paolo Menè, Francesca Romana Festuccia, Giulia Talarico, Claudia Fofi, Maria Elena Bracaccia, Ernesto Anselmo Cioffi, Fabio Mazza, Pasquale Polito, David Micarelli, Roberto Addesse, Lida Tartaglione, Sandro Feriozzi, Francesca Romana Della Rovere, Natalia Chipilova, Micol Manzuoli, Paolo Sacco, Francesca Ansaldo, Chiara Bottaro, Sonia Marre, Francesc Viazzi, Valeria Falqui, Novella Conti, Angelica Parodi, Valentina Zanetti, Francesca Cappadona, Andrea Speciale, Giancarlo Mancuso, Monica Repetto, Emanuela Chiara Vigo, Cairo Montenotte, Anna Maria Murgia, Piero Ruggenenti, Patrizia Ondei, Carmela Giuseppina Condemi, Sivia Bernardi, Francesco Scolari, Paola Gaggia, Federico Alberico, Chiara Manenti, Brunella Valzorio, Corrado Camerini, Agnese Gallico, Michela Tonoli, Federico Daffara, Roberto Zubbani, Simona Guerini, Mattia Zappa, Nicole Zambetti, Alessandra Dalla Gassa, Paola Baldan, Luca Fraizzoli, Sergio Bisegna, Nicola Palmieri, Marco Petrilli, Giusy Mandanici, Francesca Serena Stefani, Valeria Ogliari, Cristina Tantardini, Fabio Malberti, Paola Pecchini, Vincenzo La Milia, Carlo Maria Guastoni, Annalisa Neri, Marina Cornacchiari, Marco Farina, Francesco Barbisoni, Milena Maggio, Mario Cozzolino, Matthias Cassia, Michela Frittoli, Lorenza Magagnoli, Rossella De Leonardis, Roberta Casazza, Simone Vettoretti, Emanuele Grimaldi, Matteo Abinti, Francesca Maria Ida Carminati, Silvia Giuliani, Matteo Benedetti, Nicholas Delfrate, Elisa Colombo, Angela Cervesato, Enrico Eugenio Minetti, Alberto Montoli, Chiara Brunati, Valerae Li Bergolis, Maurizio Galllieni, Cristina Airaghi, Monique Buskermolen, Laura Cosmai, Maria Antonietta Orani, Cristina De Salvo, Giuseppe Vezzoli, Giorgio Slaviero, Chiara Lanzani, Federico Pieruzzi, Gina Contaldo, Barbara Trezzi, Teresa Rampino, Fabrizio Grosjean, Paola Borille, Ciro Esposito, Giuseppe Sileno, Marta Arazzi, Gianvincenzo Melfa, Mariagiulia Tettamanti, Anna Tosetti, Marco D’Amico, Maria Giulia Magatti, Silvia Peiti, Luciano Pedrini, Annalisa Feliciani, Elena Pezzini, Silvio Volmer Bertoli, Daniele Ciurlino, Silvia Tedoldi, Vania Prettico, Giulia Maria Magni, Antonietta Gazo, Maurizio Nai, Silvia Muciaccia, Graziana Battini, Lino Merlino, Paola Casanova, Federica Lencia, Maddalena Ricci, Andrea Ranghino, Mauro Valente, Carolina Finale, Eleonora Guerrini, Marta Canonici, Stefano Santarelli, Rosa Maria Agostinelli, Marina Di Luca, Mauro Martello, Cristina Silvestri, Veronica Bertuzzi, Assunta Cardillo, Valentina Nastasi, Sara Belcastro, Marco Manganaro, Emanuele Luigi Parodi, Valentina Vaccaro, Antonella Giolito, Stefano Cusinato, Michele Battista, Elena Ragazzoni, Paola Marcella Carpani, Emanuele Stramignoni, Silvana Savoldi, Guido Martina, Chiara Deagostini, Marica Magnetti, Stefania Bussolino, Federica Ventrella, Sonia Santi, Marita Marengo, Daniela Falconi, Ilaria Serra, Luca Besso, Davide Diena, Doriana Chiari Notti, Paola David, Luciana Gravellone, Corrado Vitale, Silvia Berutti, Silvia Ganci, Federica Neve Vigotti, Giulio Cesano, Maurizio Borzumati, Patrizia Bio, Stefania Gioira, Oliviero Filiberti, fabiola Pagani, Simonetta Ottone, Carlo Lomonte, Vincenzo Montinaro, Vito Pepe, Elisabetta Manno, Salvatore Di Paolo, Luigi Natalicchio, Carmela Gallo, Francesca pansini, Rossella Varvara, Filomena D’Elia, NIcola Coviello, Concetta Prisciandaro, Lucia Vernò, Fernanda Misceo, Pierfelice Zazzera, Antonella Matrella, Loreto Gesualdo, Anna Maria Di Palma, Virginia Pronzo, Federica Cassone, Salvatore Di Paolo, Tiziana Piccolo, Dora Porcelluzzi, Antonella Di Franco, Mario Giannetto, Chiara Villani, Luigi Vernaglione, Angelo Specchio, Laura Stoico, Giovanni Stallone, Vincenzo Losappio, Barbara Infante, Luigi Morrone, Anna Lisa Marangi, Angela Rodio, Christian D’Altri, Paolo Venerito, Francesca Cianciotta, Filippo Aucella, Gaetano Ferrara, Anna Rachele Nardella, Luigi Francesco Pio Morrone, Maria Grazia Corallo, Giuseppina D’Ettorre, Francesco Caccetta, Davide Gianfreda, Antonello Pani, Gianfranca Cabiddu, Stefania Caria, Maria Maddalena Romano, Ciro Adamo, Giovanni Giorgio Battaglia, Barbara Pocorobba, Emanuela Prencipe, Margherita Saraceno, Luana Scuderi, Salvatore Randone, Francesca Bruno, Rossella Rita Marchese, Antonio Granata, Daniela Puliatti, Carmelita Marcantoni, Luca Zanoli, Ambra D’anca, Domenico Santoro, Guido Gembillo, Alfio Eduardo Giuffrida, Vincenzo Labbozzetta, Angelo Tralongo, Gioacchino Li Cavoli, Carmela Zaggarigo, Paolo Conti, Sofia Giovannini, Silvia Farsetti, Pietro Claudio Giovanni Dattolo, Aris Tsalouchos, Stefano Michelassi, Marco Gallo, Irene Bandor, Nadia Sami, Daniela Riccomi, Lorena Traversari, Maria Grazia Tabbi, Maria Luisa Bonincontro, Vera Bonell, Giuliano Brunori, Diana Zarantonello, Alessandro Laudon, Antonio Selvi, Stefania Santoni, Davide Massimiani, Davide Rossi, Lorenzo Calò, Barbara Rossi, Giuseppe Scaparrotta, Fulvio Fiorini, Valentina Iacono, Carlo Rugiu, Monica Slaviero, Maurizio Nordio, Riccarda Maria Puggia, Adriana Caberlotto, Flavio Scanferla, Vincenzo Casoria, Federica Gramegna, Gina Meneghel, Ilenia Filippi, Anna Giacomini, Claudio Ronco, Anna Giuliani, Sabrina Milan Manani, Monica Zanella
Correction to: Safety and efficacy of COVID-19 vaccines in patients on dialysis: a multicentre cohort study in Italy
No full textThe COVIDVaxDia Study Group in html which currently reads Francesca Menniti-Ippolito, Roberto Da Cas, Flavia Chiarotti, Massimo Fabiani, Giuseppe Traversa, Piergiorgio Messa, Alfonso Mele, Salvatore De Masi, Francesca Colavita, Concetta Castilletti, Carmine Zoccali, Aldo Pietro Maggioni, Andrea Lorimer, Martina Ceseri, Ester Baldini, Francesca Bianchini, Laura Sarti, Giovanni Baglio, Andrea Mariano and Eva Alessi. It should read as: Francesca Menniti-Ippolito, Roberto Da Cas, Flavia Chiarotti, Massimo Fabiani, Giuseppe Traversa, Piergiorgio Messa, Alfonso Mele, Salvatore De Masi, Francesca Colavita, Concetta Castilletti, Carmine Zoccali, Aldo Pietro Maggioni, Andrea Lorimer, Martina Ceseri, Ester Baldini, Francesca Bianchini, Laura Sarti, Giovanni Baglio, Andrea Mariano & Eva Alessi, Lorenzo Di Liberato, Luigi Amoroso, Nicola Spetrino, Milva Di Giovanni, Carlo Sapio, Irma Figlia, Roberto Pititto, Teresa Papalia, Rosita Greco, Francesca Leone, Francesco Maria D’Agostino, Mariangela Campolo, Maria Rosa La Gamba, Francesca Mallamaci, Vincenzo Panuccio, Giovanna Parlongo, Giuseppe Natale, Domenico Tramontana, Ivania Maria Figliano, Santo Vitiello, Anna Maria Frangiosa, Domenico Caserta, Pasqualina Acconcia, Nunzia Paudice, Alfonso De Maio, Salvatore Cascone, Marilina Siani, Mario Cioffi, Nataliya Romanyuk, Franca Pagnano, Antonio De Donato, Ersilia Satta, Alessandra Perna, Francesco Trepiccione, Alessandro Cerrone, Gianluca Garofalo, Giancarlo Marinelli, Roberta D’Amato, Enrico De Felice, Alfredo Vacca, Salvatore Coppola, Vincenzo Cuomo, Maria Palma Iavarone, Annalisa Ciotola, Vincenzo Puglia, Pio Granato, Carla Lamberti, Giorgio Capasso, Domenico Bonanno, Marco Ventre, Veronica Amendola, Fabio Cappabianca, Elena Mancini, Davide Ricci, Daniela Cecilia Cannarile, Roberta Benevento, Bianca Perciaccante, Alda Storari, Yuri Battaglia, Giovanni Piva, Giovanni Mosconi, Alessandra Spazzoli, Paolo Ferdinando Bruno, Katia Ambri, Barbara Veterani, Sara Signorotti, Marcora Mandreoli, Renato Mario Rapanà, Maria Teresa Benedetto, Laura Patregnani, Maddalena Zambelli, Gaetano Alfano, Mariacristina Gregorini, Silvia Mattei, Francesca Iannuzzella, Elena Pelizzaro, Luca Camparini, Giuseppe Battaglino, Dino Romanini, Antonio Irlando, Lojze Celik, Giuseppa Natale, Maria Cristina Torre, Ilaria Umbro, Nicola Pirozzi, Loredana Fazzari, Lucia Pantano, Antonio Paone, Marco Galliani, Veronica Baglio, Eleonora Moscaritolo, Sabrina Fierimonte, Maria De Cristofaro, Elena Nebuloso, Paolo Menè, Francesca Romana Festuccia, Giulia Talarico, Claudia Fofi, Maria Elena Bracaccia, Ernesto Anselmo Cioffi, Fabio Mazza, Pasquale Polito, David Micarelli, Roberto Addesse, Lida Tartaglione, Sandro Feriozzi, Francesca Romana Della Rovere, Natalia Chipilova, Micol Manzuoli, Paolo Sacco, Francesca Ansaldo, Chiara Bottaro, Sonia Marre, Francesc Viazzi, Valeria Falqui, Novella Conti, Angelica Parodi, Valentina Zanetti, Francesca Cappadona, Andrea Speciale, Giancarlo Mancuso, Monica Repetto, Emanuela Chiara Vigo, Cairo Montenotte, Anna Maria Murgia, Piero Ruggenenti, Patrizia Ondei, Carmela Giuseppina Condemi, Sivia Bernardi, Francesco Scolari, Paola Gaggia, Federico Alberico, Chiara Manenti, Brunella Valzorio, Corrado Camerini, Agnese Gallico, Michela Tonoli, Federico Daffara, Roberto Zubbani, Simona Guerini, Mattia Zappa, Nicole Zambetti, Alessandra Dalla Gassa, Paola Baldan, Luca Fraizzoli, Sergio Bisegna, Nicola Palmieri, Marco Petrilli, Giusy Mandanici, Francesca Serena Stefani, Valeria Ogliari, Cristina Tantardini, Fabio Malberti, Paola Pecchini, Vincenzo La Milia, Carlo Maria Guastoni, Annalisa Neri, Marina Cornacchiari, Marco Farina, Francesco Barbisoni, Milena Maggio, Mario Cozzolino, Matthias Cassia, Michela Frittoli, Lorenza Magagnoli, Rossella De Leonardis, Roberta Casazza, Simone Vettoretti, Emanuele Grimaldi, Matteo Abinti, Francesca Maria Ida Carminati, Silvia Giuliani, Matteo Benedetti, Nicholas Delfrate, Elisa Colombo, Angela Cervesato, Enrico Eugenio Minetti, Alberto Montoli, Chiara Brunati, Valerae Li Bergolis, Maurizio Galllieni, Cristina Airaghi, Monique Buskermolen, Laura Cosmai, Maria Antonietta Orani, Cristina De Salvo, Giuseppe Vezzoli, Giorgio Slaviero, Chiara Lanzani, Federico Pieruzzi, Gina Contaldo, Barbara Trezzi, Teresa Rampino, Fabrizio Grosjean, Paola Borille, Ciro Esposito, Giuseppe Sileno, Marta Arazzi, Gianvincenzo Melfa, Mariagiulia Tettamanti, Anna Tosetti, Marco D’Amico, Maria Giulia Magatti, Silvia Peiti, Luciano Pedrini, Annalisa Feliciani, Elena Pezzini, Silvio Volmer Bertoli, Daniele Ciurlino, Silvia Tedoldi, Vania Prettico, Giulia Maria Magni, Antonietta Gazo, Maurizio Nai, Silvia Muciaccia, Graziana Battini, Lino Merlino, Paola Casanova, Federica Lencia, Maddalena Ricci, Andrea Ranghino, Mauro Valente, Carolina Finale, Eleonora Guerrini, Marta Canonici, Stefano Santarelli, Rosa Maria Agostinelli, Marina Di Luca, Mauro Martello, Cristina Silvestri, Veronica Bertuzzi, Assunta Cardillo, Valentina Nastasi, Sara Belcastro, Marco Manganaro, Emanuele Luigi Parodi, Valentina Vaccaro, Antonella Giolito, Stefano Cusinato, Michele Battista, Elena Ragazzoni, Paola Marcella Carpani, Emanuele Stramignoni, Silvana Savoldi, Guido Martina, Chiara Deagostini, Marica Magnetti, Stefania Bussolino, Federica Ventrella, Sonia Santi, Marita Marengo, Daniela Falconi, Ilaria Serra, Luca Besso, Davide Diena, Doriana Chiari Notti, Paola David, Luciana Gravellone, Corrado Vitale, Silvia Berutti, Silvia Ganci, Federica Neve Vigotti, Giulio Cesano, Maurizio Borzumati, Patrizia Bio, Stefania Gioira, Oliviero Filiberti, fabiola Pagani, Simonetta Ottone, Carlo Lomonte, Vincenzo Montinaro, Vito Pepe, Elisabetta Manno, Salvatore Di Paolo, Luigi Natalicchio, Carmela Gallo, Francesca pansini, Rossella Varvara, Filomena D’Elia, NIcola Coviello, Concetta Prisciandaro, Lucia Vernò, Fernanda Misceo, Pierfelice Zazzera, Antonella Matrella, Loreto Gesualdo, Anna Maria Di Palma, Virginia Pronzo, Federica Cassone, Salvatore Di Paolo, Tiziana Piccolo, Dora Porcelluzzi, Antonella Di Franco, Mario Giannetto, Chiara Villani, Luigi Vernaglione, Angelo Specchio, Laura Stoico, Giovanni Stallone, Vincenzo Losappio, Barbara Infante, Luigi Morrone, Anna Lisa Marangi, Angela Rodio, Christian D’Altri, Paolo Venerito, Francesca Cianciotta, Filippo Aucella, Gaetano Ferrara, Anna Rachele Nardella, Luigi Francesco Pio Morrone, Maria Grazia Corallo, Giuseppina D’Ettorre, Francesco Caccetta, Davide Gianfreda, Antonello Pani, Gianfranca Cabiddu, Stefania Caria, Maria Maddalena Romano, Ciro Adamo, Giovanni Giorgio Battaglia, Barbara Pocorobba, Emanuela Prencipe, Margherita Saraceno, Luana Scuderi, Salvatore Randone, Francesca Bruno, Rossella Rita Marchese, Antonio Granata, Daniela Puliatti, Carmelita Marcantoni, Luca Zanoli, Ambra D’anca, Domenico Santoro, Guido Gembillo, Alfio Eduardo Giuffrida, Vincenzo Labbozzetta, Angelo Tralongo, Gioacchino Li Cavoli, Carmela Zaggarigo, Paolo Conti, Sofia Giovannini, Silvia Farsetti, Pietro Claudio Giovanni Dattolo, Aris Tsalouchos, Stefano Michelassi, Marco Gallo, Irene Bandor, Nadia Sami, Daniela Riccomi, Lorena Traversari, Maria Grazia Tabbi, Maria Luisa Bonincontro, Vera Bonell, Giuliano Brunori, Diana Zarantonello, Alessandro Laudon, Antonio Selvi, Stefania Santoni, Davide Massimiani, Davide Rossi, Lorenzo Calò, Barbara Rossi, Giuseppe Scaparrotta, Fulvio Fiorini, Valentina Iacono, Carlo Rugiu, Monica Slaviero, Maurizio Nordio, Riccarda Maria Puggia, Adriana Caberlotto, Flavio Scanferla, Vincenzo Casoria, Federica Gramegna, Gina Meneghel, Ilenia Filippi, Anna Giacomini, Claudio Ronco, Anna Giuliani, Sabrina Milan Manani, Monica Zanella
Safety and efficacy of COVID-19 vaccines in patients on dialysis: a multicentre cohort study in Italy
No full textBackground The aim of this study was to evaluate the efficacy and safety of COVID-19 vaccines in patients undergoing haemodialysis in Italy compared to the general population.Methods In this cohort study, 118 dialysis centres from 18 Italian Regions participated. Individuals older than 16 years on dialysis treatment for at least 3 months, who provided informed consent were included. We collected demographic and clinical information, as well as data on vaccination status, hospitalisations, access to intensive care units and adverse events. We calculated the incidence, hospitalisation, mortality, and fatality rates in the vaccinated dialysis cohort, adjusted for several covariates. The incidence rates of infection in the dialysis cohort and the general population were compared through Standardised Incidence Rate Ratio.Results The study included 6555 patients vaccinated against SARS-CoV-2 infection according to the schedule recommended in Italy. Between March 2021 and May 2022, there were 1096 cases of SARS-CoV-2 infection, with an incidence rate after completion of the three-dose vaccination cycle of 37.7 cases per 100 person-years. Compared to the general population, we observed a 14% reduction in the risk of infection for patients who received three vaccine doses (Standardised Incidence Rate Ratio: 0.86; 95% Confidence Interval: 0.81-0.91), whereas no statistically significant differences were found for COVID-19-related hospitalisations, intensive care unit admissions or death. No safety signals emerged from the reported adverse events.Conclusions The vaccination program against SARS-CoV-2 in the haemodialysis population showed an effectiveness and safety profile comparable to that seen in the general population
Impact of COVID-19 vaccines in patients on hemodialysis: an Italian multicentre cohort study
No full textBackground The aim of this study was to evaluate the impact on the national health system of COVID-19 infection in vaccinated patients undergoing haemodialysis.MethodsFrom the cohort of vaccinated dialysis patients enrolled in 118 dialysis centres, we calculated hospitalisation incidence in COVID-19-infected subjects. COVID-19-related hospitalisations and ICU admissions were analysed over two time periods (prior to administration of the third dose and following administration of the third dose of vaccine) and adjusted for several co-variates. Using the general population as the reference, we then calculated the Standardized Incidence Ratio (SIR) of hospitalisation.ResultsEighty-two subjects out of 1096 infected patients were hospitalised (7.5%) and sixty-four hospitalisations occurred among the 824 infected persons after the third dose. Age >= 60 years (Adj RR 2.91; 95% CI 1.34-6.30) and lung disease (Adj RR = 2.45; 95% CI 1.32-4.54) were the only risk factors associated with hospitalisation. The risk of ICU admission in the second time period (Time 2) was reduced by 86% (RR = 0.14; 95% CI 0.03-0.71) compared to the first time period (Time 1). The SIR of hospitalisation (SIR 14.51; 95% CI 11.37-17.65) and ICU admission (SIR 14.58; 95% CI 2.91-26.24) showed an increase in the number of events in dialysis patients compared to the general population.ConclusionsOur analysis revealed that while the second variant of the virus increased infection rates, it was concurrently associated with mitigated severity of infections. Dialysis patients exhibited a higher susceptibility to both COVID-19 hospitalisation and ICU admission than the general population throughout the pandemic
