15 research outputs found
Bifurcation of Limit Cycle for Three-Dimensional Lotka-Volterra Dynamical System
No full textAbstract In this paper, we give a survey of the use of the Hopf bifucation theorem in a special subset of a three-dimensional Lotka-Volterra dynamical system. We show that a stable limit cycle can bifurcate. Our main result obtained is illustrated with examples and simulations. Mathematics Subject Classi…cation: 34C05, 37G1
Periodic solutions of a differential perturbed system via the averaging theory and the Melnikov method
No full textIn this paper, we will study the maximum number of limit cycles of a perturbed differential system with respect to its parameters which appear in the system specially on the degree of the polynomials. For this we will use two methods namely the averaging theory of first order and the method of Melnikov on the same system to provide an upper bound for the number of periodic solutions which can bifurcate from the center with ε = 0. In the end, we will present some numerical examples in order to illustrate the theoretical results given by the averaging theory and Melnikov one
IN-VITRO ANTICOAGULANT EFFECT OF AERIAL PARTS EXTRACTS OF YEMENI FAGONIA SCHWEINFURTHII HADIDI
No full textBackground: Blood coagulation is a quick and effective process that results in the creation of clots, which demands to monitor. Many illness disorders include an abnormality in blood coagulation. This study examined the in vitro effects of methanol, ethyl acetate, and n-hexane extracts from aerial parts of Fagonia schweinfurthii Hadidi on healthy human volunteers' blood coagulation. 
Methods: The Secondary metabolites were extracted from dried and crushed F. schweinfurthii aerial parts using n-hexane, ethyl acetate, and methanol, respectively. Additionally, the extracts were tested in vitro at different concentrations (10-100 µg/ml) on the blood coagulation profile, prothrombin time (PT), and activated partial thromboplastin time (a PTT) of apparently healthy human volunteers.
Results: Methanol, ethyl acetate, and n-hexane extracts of F. schweinfurthii aerial parts significantly (p˃0.05) prolonged PT and PTT in the blood of healthy human volunteers with Ethyl acetate and methanol extracts recorded the largest prolongation of PT and PTT correspondingly. The highest PT and PTT prolongation was achieved at 100µg/ml, and the least prolongation time was obtained at 10µg/ml.
Conclusion: These findings displayed that F. schweinfurthii aerial parts contain phytochemical constituents with anticoagulant characteristics and could be used to treat blood clotting disorders.

Peer Review History: 
Received: 26 April 2022; Revised: 12 June; Accepted: 30 June, Available online: 15 July 2022
Academic Editor: Dr. DANIYAN Oluwatoyin Michael, Obafemi Awolowo University, ILE-IFE, Nigeria, [email protected]
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. 
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 5.5/10
Average Peer review marks at publication stage: 7.0/10
Reviewers:
Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622, Giza, Egypt, [email protected] 
Dr. Marwa A. A. Fayed, University of Sadat City, Egypt, [email protected]
Prof. Dr. Hüsniye Kayalar, Ege University, Turkey, [email protected]
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An Interdisciplinary Study of Narrative Structure in Dash Akol as a Short Story and Dash Akol as a Movie
No full textThis paper undertakes an interdisciplinary study of the short story “Dash Akol” and the movie adapted from it. “Dash Akol” is a short story written by a famous Iranian author Sadeq Hedayat in 1932. Hedayat’s “Dash Akol” was made into a movie in 1971 by Masoud Kimiai. There are some discrepancies between the short story “Dash Akol” and the movie, triggering a number of significant implications. This article discusses these discrepancies along with Hedayat’s and Kimiai’s narrative techniques. To this end, it applies Genett’s (1988) Narrative Discourse and his three main narrative methods: narrating, characterization, and focalization. Meanwhile, it brings in Rimmon-Kenen’s (2002) strategy to study characters, and Stam and Burgoyne and Flitterman-lewis (2005) to show the ways in which the movie has deviated from the story. In terms of characterization, it studies traits such as, action, speech, naming and setting
Generic probabilistic inversion technique for geotechnical and transportation engineering applications
No full textA wide range of important problems in civil engineering can be classified as inverse problems. In such problems, the observational data related to the performance of a system is known, and the characteristics of the system or the input are sought. There are two general approaches to the solution of inverse problems: deterministic and probabilistic. Traditionally, inverse problems in civil engineering have been solved using a deterministic approach. In this approach, the objective is to find a model of the system that its theoretical response best fits the observed data. In deterministic approach to the solution of inverse problems, it is implicitly assumed that the uncertainties in data and theoretical models are negligible. However, this assumption is not valid in many applications, and therefore, effects of data and modeling uncertainties on the obtained solution should be evaluated. In this dissertation, a general probabilistic approach to the solution of the inverse problems is introduced, which offers the framework required to obtain uncertainty measures for the solution. Techniques for direct analytical evaluation and numerical approximation of the probabilistic solution using Monte Carlo Markov Chains (MCMC), with and without Neighborhood Algorithm (NA) approximation, are introduced and explained. The application of the presented concepts and techniques are then illustrated for three important classes of inverse problems in geotechnical and transportation engineering as application examples. These applications are: Falling Weight Deflectometer (FWD) backcalculation, model calibration based on geotechnical instrument measurements, and seismic waveform inversion for shallow subsurface characterization. For each application, the probabilistic formulation is presented; the solution is obtained; and the advantages of the probabilistic approach are illustrated and discussed.Ph. D.Includes bibliographical references
Use of dictation as a tool to decrease documentation errors in electronic health records
No full textBackground: Use of Electronic Health Records is increasing. Copy-and-paste function is frequently used with higher rates of documentation errors. Studies to determine the nature of such errors are needed.Objectives: Determination of the effect of implementing a dictation system for completing notes on the quality of clinical documentation. We hypothesized that implementation of the dictation system for note writing would decrease the rate of errors in the progress notes as well as decrease the rate of copying and pasting. Design/Methods: A prospective interventional study in inpatient medical service for six months’ duration starting in July 2016. Resident physicians’ charts were reviewed by the attending physician on a daily basis. This study was done in a community based hospital affiliated to a university program. Residents’ physicians included Internal Medicine, Transitional year and Combined Internal Medicine Pediatrics residents. Charts reviewed for hospitalized patients. A total of 54 residents were offered a pre-intervention survey indicating their subjective use of copy/paste function. Response rate of 85.18%. Progress notes were reviewed on a daily basis for residents on their inpatient rotation. A total of 621 notes were reviewed. Results: Percentage of notes copied prior to the intervention was 92.73% which decreased to 49.71% post-intervention (RR of 0.54, 95% CI 0.48 0.60 Z statistic 11.005 with p-value <0.0001). Of the copied notes percentage of errors pre-intervention was 58% with no errors identified post-intervention (RR of 0.005, 95% CI 0.0003 0.0795 Z statistic 3.752 with p-value 0.0002). Most of the errors are from notes copied by the same author (85.8%). The most common documentation error was in the physical examination section. Conclusion: Implementing a dictation system eliminated documentation errors over our six months’ study. Further studies are needed to check long effects of using such systems on documentation error
Assessment of diet composition of free-ranging antelopes (Addax nasomaculatus) by the combination of microhistological procedures and n-alkanes and long-chain alcohols as faecal markers
No full textUnderstanding herbivore foraging behaviour is crucial for adequate wildlife management decisions. This study assessed the diet composition of free-ranging antelope Addax (Addax nasomaculatus De Blainville, 1816). Samples collected during the spring season were analyzed using microhistological procedures along with n-alkanes and long-chain alcohols as fecal markers. Twelve animals were monitored and fresh fecal samples were collected daily during a seven-day period. Diet composition estimates obtained by both methods were similar and indicate that (Stipagrostis pungens subsp. (Desf.) De Winter) was the main diet component followed by (Fagonia glutinosa var. (Delile.) nuda Hadidi), (Helianthemum kahiricum var. libycum (Pomel.) Batt.) and (Hamada schmittiana (Pomel.) Botsch.). Data showed that Addax have mixed diets composed of perennial woody and herbaceous plant species depending on their availability. The four species most selected by the animals were also the most abundant species in the plant cover. By contrast, species that accounted for less than 5% of the plant cover were not present in the fecal samples. Results of this study represent a single grazing season and, for that reason, further studies are required to fully understand how the antelopesâ grazing behaviour varies with seasonal changes in vegetation cover.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
Suboptimal management of rheumatoid arthritis in the Middle East and Africa: Could the EULAR recommendations be the start of a solution?
No full text[No abstract available]Adelowo OO, 2010, CLIN RHEUMATOL, V29, P593, DOI 10.1007-s10067-009-1355-0; Al-Dalaan A, 1998, ANN SAUDI MED, V18, P396; Aletaha D, 2010, ANN RHEUM DIS, V69, P1580, DOI 10.1136-ard.2010.138461; Badsha H, 2008, CLIN RHEUMATOL, V27, P739, DOI 10.1007-s10067-007-0782-z; Callahan L F, 1995, Arthritis Care Res, V8, P229, DOI 10.1002-art.1790080406; Davatchi F, 2008, J RHEUMATOL, V35, P1384; Davatchi F, 2009, CLIN RHEUMATOL, V28, P1267, DOI 10.1007-s10067-009-1234-8; Gabriel SE, 2001, RHEUM DIS CLIN N AM, V27, P269, DOI 10.1016-S0889-857X(05)70201-5; Kalla AA, 2003, BEST PRACT RES CL RH, V17, P863, DOI 10.1016-S1521-6942(03)00047-0; Lee DM, 2001, LANCET, V358, P903, DOI 10.1016-S0140-6736(01)06075-5; Lundkvist J, 2008, EUR J HEALTH ECON, V8, pS49, DOI 10.1007-s10198-007-0088-8; Malemba JJ, 2008, CLIN RHEUMATOL, V27, P47, DOI 10.1007-s10067-007-0650-x; Minaur NJ, 2004, J RHEUMATOL, V31, P3; Owino B O, 2009, East Afr Med J, V86, P204; Parker Romy, 2010, BMC Musculoskelet Disord, V11, P2, DOI 10.1186-1471-2474-11-2; Rkain H, 2006, JOINT BONE SPINE, V73, P278, DOI 10.1016-j.jbspin.2005.03.021; Scott DL, 2010, LANCET, V376, P1094, DOI 10.1016-S0140-6736(10)60826-4; Singh JA, 2012, ARTHRIT CARE RES, V64, P625, DOI 10.1002-acr.21641; Singwe-Ngandeu M, 2007, East Afr Med J, V84, P404; Smolen JS, 2010, ANN RHEUM DIS, V69, P964, DOI 10.1136-ard.2009.126532; Solomon A, 2005, SEMIN ARTHRITIS RHEU, V35, P122, DOI 10.1016-j.semarthrit.2005.05.005; Tikly Mohammed, 2003, MedGenMed, V5, P2; Woolf AD, 2003, B WORLD HEALTH ORGAN, V81, P646; World Health Organisation, 2003, WHO TECHN REP SER, V919; World Health Organization, 2011, CHRON DIS HLTH PROM; World Health Organization, 2011, GLOB HLTH OBS DAT RE; World Health Organization, 2008, GLOB BURD DIS 2004 U32
Nurturing Our Young
No full textSession presented on Monday, July 27, 2015: Purpose: Historically nurses have been known to \u27eat their young\u27. Within the nursing department at a MidwesteRNniversity, the faculty has adopted a new approach to relationships with future nursing students. The nursing department has incorporated activities to \u27nurture our young\u27. At the university nursing faculty are not typically engaged with freshman nursing major students. Because the faculty in the nursing department usually only teach nursing subject classes, they do not have the exposure to the pre-nursing students. The nursing program starts during the junior year of classes. Last year the author expressed a desire to be more involved with the freshman pre-nursing students. The university has offered best practice retention strategies for freshman for several years. These strategies include learning and living communities; student success courses; new student orientation; and focused advising (Hanover Research, 2014). Methods: In addition to the strategies already implemented by the university, the nursing department wanted to develop a mentoring program for the freshman to help \u27nurture our young\u27. Mentoring is a development process where a more experienced person guides a less experienced person in a given situation for an expressed purpose or outcome (Marquis & Huston, 2015). Mentoring at the college level helps develop social support, role modeling, and opportunities to develop new skills (DuBois & SilverthoRN2005). The goal of formal mentoring programs is to provide collegiality, networking, listening, & encouragement to the mentees. Research shows that if college students are retained as freshmen to the sophomore year, persistence to graduation is greater than 80 percent (Hadidi, Lindquist, & Buckwalter, 2013). The university requires all freshman students enroll in the freshman seminar course (student success course). However, the university does not require all departments to offer a learning and living community (LLC). As the nursing department was pleased with the positive effects of the mentoring program, the faculty also saw the need for the LLC to help \u27nurture our young\u27. For the academic year of 2014-2015 the nursing department developed the Nightingale Power LLC for freshman nursing major students. The LLC started with recruitment at the student recognition programs and the spring enrollment sessions. Once the LLC was identified the Nightingale Power LLC committee chose peer mentors to help with the activities and bonding. The peer mentors were chosen based on their nursing major and involvement with campus activities. The LLC participates in social activities coordinated by the Nightingale Power committee. These activities include the Nightingale Power orientation, back to school picnic, the homecoming float parade, the state nursing legislative trip, and the mentoring project. In addition to social activities the LLC participates in academic classes together to further develop their study habits and collegiality. The LLC courses in the first semester are taught by the nursing department faculty. The students also live on the same floor in the residential housing. The peer mentors and faculty provide consultation time throughout the semester in the students\u27 residential building. The lead coordinator of the LLC also serves as the students\u27 academic advisor. The advisor meets with the freshman three times each semester to provide concise, individualized advising. Positive emotions can develop from relationships with peers in residence halls, faculty instructors in the major, and academic major advisors (Vianden & Barlow, 2014). A final activity to promote persistence and retention in the nursing program to help \u27nurture our young\u27 is an assignment in the Leadership practicum course. The final semester senior nursing students are paired with junior nursing students as these students are in their first semester of the nursing program. The senior student meets with the junior student in an informal setting to answer questions about the program in general or specifics related to their junior nursing classes. Then the senior meets the junior for a clinical at the hospital. The senior is the junior\u27s mentor for the clinical day. They work together to care for the junior\u27s assigned patient. The senior is present to guide the junior and provide leadership. Results: The mentoring project piloted in spring 2014 with 11 mentors and 11 mentees. The mentors were volunteers from the senior nursing class. The mentees were volunteers from the freshman pre-nursing students. The students were paired and participated in structured activities to develop their mentoring relationship. The students participated in a total of seven activities together. Throughout the project the students completed surveys to assess their mentoring relationship and the development of their communication and self-confidence. At the completion of the spring 2014 pilot project 82% of the freshman stated they would continue with nursing as their major. The author plans to continue this project yearly hoping to increase participation. Midway through the academic year the Nightingale Power LLC persistence rate is 86%. Four students have identified that nursing is not for them and have asked for different majors. The Nightingale Power LLC has provided the students an earlier introduction to the nursing department faculty and current nursing students. Both junior and senior nursing students have expressed satisfaction with the Mentoring assignment. Conclusion: The author is the coordinator of the mentoring project; lead coordinator of the Nightingale Power LLC; and the lead faculty for the Leadership practicum course. The mentoring project, the Nightingale Power LLC, and the Leadership practicum mentoring assignment are all ways that the nursing department faculty \u27nurtures our young\u27. The nursing department strives to provide an encouraging environment for the nursing students to promote their interest in and commitment to nursing as a profession
The practical value of biologics registries in Africa and Middle East: Challenges and opportunities
No full textBiologics, including tumor necrosis factor (TNF) inhibitors, are increasingly used for the treatment of inflammatory conditions such as rheumatoid arthritis (RA), psoriatic arthritis, and ankylosing spondylitis. The efficacy of these drugs has been demonstrated in randomized controlled trials (RCTs). However, these studies are conducted in controlled environments, and the results may not necessarily reflect clinical outcomes in daily clinical practice. In Europe and other western countries, numerous biologics registries that enroll and monitor patients receiving biologics have been established. These registries follow patients irrespective of whether they continue with the initial biologic drug. Thus, real-life efficacy data from these registries can be used to assess the long-term safety of biologics through longitudinal studies. In Africa and Middle East (AFME), such registries currently exist only in Morocco and South Africa. In light of the increasing availability of biologics and scarcity of long-term safety data of these agents in the AFME population, there is a need to establish biologics registries in other countries across the region. This review discusses the value of biologics registries versus RCTs as well as safety and efficacy data from observational studies presented as lessons from well-established biologics registries. In addition, the rationale for establishing such registries in the AFME region is also presented. © 2012 Clinical Rheumatology.[Anonymous], 2009, WORK WHO E MEDITERRA; [Anonymous], 2011, ENV MIDDL E REG INT, V111; Askling J, 2006, ANN RHEUM DIS, V65, P707, DOI 10.1136-ard.2005.045872; Askling J, 2009, ANN RHEUM DIS, V68, P648, DOI 10.1136-ard.2007.085852; Askling J, 2011, PHARMACOEPIDEM DR S, V20, P119, DOI 10.1002-pds.2046; Badsha H, 2008, CLIN RHEUMATOL, V27, P739, DOI 10.1007-s10067-007-0782-z; Bernatsky S, 2010, J RHEUMATOL, V37, P928, DOI 10.3899-jrheum.091107; Bongartz T, 2006, JAMA-J AM MED ASSOC, V295, P2275, DOI 10.1001-jama.295.19.2275; Brennan A, 2007, RHEUMATOLOGY, V46, P1345, DOI 10.1093-rheumatology-kem115; Carmona L, 2011, SEMIN ARTHRITIS RHEU, V41, P71, DOI 10.1016-j.semarthrit.2010.08.005; Carmona L, 2007, ANN RHEUM DIS, V66, P880, DOI 10.1136-ard.2006.067660; Coffin CS, 2011, INFLAMM BOWEL DIS, V17, P479, DOI 10.1002-ibd.21336; Dixon WG, 2010, ANN RHEUM DIS, V69, P1596, DOI 10.1136-ard.2009.125526; Dixon WG, 2007, ARTHRITIS RHEUM, V56, P2896, DOI 10.1002-art.22808; Dixon WG, 2006, ARTHRITIS RHEUM, V54, P2368, DOI 10.1002-art.21978; Dixon WG, 2007, ARTHRITIS RHEUM, V56, P2905, DOI 10.1002-art.22809; Dixon WG, 2010, ANN RHEUM DIS, V69, P522, DOI 10.1136-ard.2009.118935; Dixon WG, 2010, ARTHRIT CARE RES, V62, P755, DOI 10.1002-acr.20129; Galloway JB, 2011, RHEUMATOLOGY, V50, P1341, DOI 10.1093-rheumatology-ker146; Garcia-Doval I, 2010, ANN RHEUM DIS, V69, P1751, DOI 10.1136-ard.2009.125658; Gomez-Reino JJ, 2003, ARTHRITIS RHEUM, V48, P2122, DOI 10.1002-art.11137; Hetland ML, 2010, ARTHRITIS RHEUM-US, V62, P22, DOI 10.1002-art.27227; Jacobsson LTH, 2007, ANN RHEUM DIS, V66, P670, DOI 10.1136-ard.2006.062497; Karlsson J A, 2008, Rheumatology (Oxford), V47, P507, DOI 10.1093-rheumatology-ken034; Kievit W, 2007, ANN RHEUM DIS, V66, P1473, DOI 10.1136-ard.2007.072447; Kramvis A, 2007, HEPATOL RES, V37, pS9, DOI 10.1111-j.1872-034X.2007.00098.x; Kvien TK, 2005, CLIN EXP RHEUMATOL, V23, pS188; Lie EU, 2010, ARTHRITIS RHEUM S10, V62, P377; Listing J, 2006, ARTHRITIS RES THER, V8, DOI 10.1186-ar1933; Madhava V, 2002, LANCET INFECT DIS, V2, P293, DOI 10.1016-S1473-3099(02)00264-5; Marchesoni A, 2009, ANN NY ACAD SCI, V1173, P837, DOI 10.1111-j.1749-6632.2009.04621.x; Maziak W, 2006, BRIT MED J, V333, P815, DOI 10.1136-bmj.39006.478796.80; Ornbjerg LM, 2010, ARTHRITIS RHEUM S10, V62, P1841; Pallavicini FB, 2010, AUTOIMMUN REV, V9, P175, DOI 10.1016-j.autrev.2009.07.006; Salmon-Ceron D, 2011, ANN RHEUM DIS, V70, P616, DOI 10.1136-ard.2010.137422; Scott David L, 2009, Best Pract Res Clin Rheumatol, V23, P13, DOI 10.1016-j.berh.2008.12.009; Smolen JS, 2010, ANN RHEUM DIS, V69, P964, DOI 10.1136-ard.2009.126532; Strangfeld A, 2009, ANN RHEUM DIS, V68, P1856, DOI 10.1136-ard.2008.098467; Strangfeld A, 2009, JAMA-J AM MED ASSOC, V301, P737, DOI 10.1001-jama.2009.146; Symmons D, 2000, GLOBAL BURDEN RHEUMA; Tubach F, 2009, ARTHRITIS RHEUM, V60, P1884, DOI 10.1002-art.24632; World Health Organisation Regional Office for Africa, 2010, ACH SUST HLTH DEV AF; World Health Organization, GROW THREATS HEP B C; World Health Organization, CARD DIS; World Health Organization, GLOB TUB CONTR; World Health Organization, 2011, MED CTR CARD DIS FAC; Zink A, 2009, ANN RHEUM DIS, V68, P1240, DOI 10.1136-ard.2008.09192622
