1,638 research outputs found

    Contact sensitization in very young children.

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    BACKGROUND: Allergic contact dermatitis is an increasingly recognized clinical problem in children. OBJECTIVE: The aim of our study was to evaluate contact sensitization in patients younger than 3 years of age with suspected contact dermatitis. METHODS: During a 6-year period (2002-2008), 321 children underwent routine patch testing with a screening pediatric standard series of 30 allergens. RESULTS: Two hundred children (62.3%; 102 girls and 98 boys aged 3-36 months [mean age 27 + 5.6 months]) developed at least one positive reaction. The most frequent reactions were to nickel sulfate (26.8%), followed by potassium dichromate (9%), cocamidopropylbetaine (7.2%), cobalt chloride (6.2%), neomycin sulfate (5%), and methylchloroisothiazolinone/methylisothiazolinone (4.4%). The prevalence of contact sensitization was similar in children with (61.3%) and without (63%) atopic dermatitis. LIMITATIONS: The prevalence of contact sensitization in children younger than 3 years of age was not compared with the prevalence in older children. CONCLUSION: A high prevalence of contact sensitization was found in preschool children, even younger than 3 years of age. Patch testing should be considered in this age group when persistent dermatitis does not respond to conventional treatmen

    VCC-LF dataset

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    This is readme for VCC-LF dataset. This dataset provides light field mat files that capture by Lytro I. The light field resolusion is [h,w,u,v,d]. If you use these data or our toolkit code, please cite our paper properly @inproceedings{ lirsiggraphasia2019, title={Hierarchical and View-invariant Light Field Segmentation by Maximizing Entropy Rate on 4D Ray Graphs}, author={Li, Rui and Heidrich, Wolfgang}, booktitle={ACM Transactions on Graphics (Proc. SIGGRAPH Asia)}, year={2019}, publisher={ACM}

    LF-copying without LF

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    AbstractA copying approach to ellipsis is presented, whereby the locus of copying is not a level of derived syntactic structure (LF), but rather the derivation itself. The ban on preposition stranding in sprouting follows without further stipulation, and other, seemingly structure sensitive, empirical generalizations about elliptical constructions, including the preposition stranding generalization, follow naturally as well. Destructive operations which ‘repair’ non-identical antecedents are recast in terms of exact identity of derivations with parameters. In the context of a compositional semantic interpretation scheme, the derivational copying approach to ellipsis presented here is revealed to be a particular instance of a proform theory, thus showing that the distinctions between, and arguments about, syntactic and semantic theories of ellipsis need to be revisited

    Congenital localized scleroderma

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    OBJECTIVES: Juvenile localized scleroderma (JLS) usually has its onset during later childhood. This report describes the clinical and serologic features of six children with congenital localized scleroderma (CLS). STUDY DESIGN: A large, multinational study was conducted among pediatric rheumatology and dermatology centers by collecting information on demographics, family history, triggering environmental factors, clinical features, laboratory reports, and treatment of patients with JLS. Patients with onset at birth were carefully examined. RESULTS: Among 750 patients with JLS, 6 patients (0.8%) had scleroderma-related lesions at birth. Female-to-male ratio was 2:1. All patients had linear scleroderma, in four involving the face with en coup de sabre appearance. Two patients were misdiagnosed as having skin infection, one nevus, one salmon patch, and two undefined skin lesions. The mean diagnostic delay was 3.9 years. In comparison with the group of 733 patients with late-onset JLS, CLS presented a significantly more prolonged disease duration at diagnosis and a higher frequency of en coup de sabre subtypes. CONCLUSIONS: Congenital localized scleroderma is a rare and probably underestimated condition in neonates. The linear subtype was the exclusive manifestation of the disease. CLS should be included in the differential diagnosis of infants with cutaneous erythematous fibrotic lesions to avoid functional and aesthetic sequelae and to allow prompt therapy

    Polynomial Approximation in Ep(D) with 0 < p < 1

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    AbstractIn this paper, we construct approximants by means of interpolation polynomialsto prove Jackson′s theorem and the Bernstein inequality in Ep(D) with 0 < p < 1

    Mean Convergence of Interpolation Polynomials in a Domain with Corners

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    AbstractIn this paper, we prove mean convergence of interpolation polynomials in a domain with some corners

    Machine learning and digital twins: monitoring and control for dynamic security in power systems

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    The reader of the chapter will be able to connect techniques from machine learning (ML) and digital twins (DTs) to gain insights for monitoring and control of (dynamic) security for electrical power systems. DTs are validated and verified high-fidelity (hf) models providing high simulation accuracy. DTs can be used for simulation of the supervised process of system operation and are therefore able to provide synthetic studied data, where measurement data are scarce. However, for some real-time applications in monitoring and control, such high-fidelity simulation models are not appropriate due to the corresponding computational barrier. There, ML aims to create an application-specific, low-fidelity (lf) approximation of the digital twin. Such trained lf models are used in real-time applications where computational time is scarce and lf information is sufficient. The conceptual intersection of hf and lf models has been little explored and becomes increasingly complex. This chapter aims to provide a conceptual overview of how such hf and lf models can be combined. This chapter is split into two parts where the first part is to introduce ML, lf models, and digital twins, hf models, for power systems analysis, and the second chapter is to use these two types of models to form purpose-driven surrogate lf models, illustrated on the example of dynamic security assessment (DSA). In the first part, the concepts for using DTs as hf models for online power system studies and their corresponding tuning of model parameters are introduced. Subsequently, ML i.e., lf models, are introduced and their corresponding training frameworks. Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Intelligent Electrical Power Grid

    Profile of clindamycin phosphate 1.2%/benzoyl peroxide 3.75% aqueous gel for the treatment of acne vulgaris

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    Tuyet A Nguyen,1,2 Lawrence F Eichenfield1,31Division of Pediatric and Adolescent Dermatology, Rady Children&#39;s Hospital, San Diego, CA, 2Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, 3Department of Dermatology, University of California, San Diego, La Jolla, CA, USA Abstract: Acne vulgaris is a common and chronic skin disease, and is a frequent source of morbidity for affected patients. Treatment of acne vulgaris is often difficult due to the multifactorial nature of this disease. Combination therapy, such as that containing clindamycin and benzoyl peroxide, has become the standard of care. Several fixed formulations of clindamycin 1% and benzoyl peroxide of varying concentrations are available and have been used with considerable success. The major limitation is irritation and dryness from higher concentrations of benzoyl peroxide, and a combination providing optimal efficacy and tolerability has yet to be determined. Recently, a clindamycin and benzoyl peroxide 3.75% fixed combination formulation was developed. Studies have suggested that this formulation may be a safe and effective treatment regimen for patients with acne vulgaris. Here, we provide a brief review of acne pathogenesis, benzoyl peroxide and clindamycin, and profile a new Clindamycin-BP 3.75% fixed combination gel for the treatment of moderate-to-severe acne vulgaris. Keywords: acne vulgaris, benzoyl peroxide, clindamyci

    Deep spectroscopic luminosity function of Abell 85 : no evidence for a steep upturn of the faint-end slope

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    IA, AD and ALS acknowledge partial support from the INFN grant InDark and from the grant Progetti di Ateneo TO Call 2012 0011 ‘Marco Polo’ of the University of Torino.We present a new deep determination of the spectroscopic luminosity function (LF) within the virial radius of the nearby and massive Abell 85 (A85) cluster down to the dwarf regime (M* + 6) using Very Large Telescope/Visible Multi-Object Spectrograph (VLT/VIMOS) spectra for ∼2000 galaxies with mr ≤ 21 mag and 〈μe,r〉 ≤ 24 mag arcsec−2. The resulting LF from 438 cluster members is best modelled by a double Schechter function due to the presence of a statistically significant upturn at the faint end. The amplitude of this upturn (αf ~ -1.58+0.19-0.15), however, is much smaller than that of the Sloan Digital Sky Survey (SDSS) composite photometric cluster LF by Popesso et al., αf ∼ −2. The faint-end slope of the LF in A85 is consistent, within the uncertainties, with that of the field. The red galaxy population dominates the LF at low luminosities, and is the main factor responsible for the upturn. The fact that the slopes of the spectroscopic LFs in the field and in a cluster as massive as A85 are similar suggests that the cluster environment does not play a major role in determining the abundance of low-mass galaxies.Peer reviewe

    An Auto-Zero-Stabilized Voltage Buffer With a Quiet Chopping Scheme and Constant Sub-pA Input Current

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    This article describes an auto-zero stabilized voltage buffer that achieves low offset and low noise with sub-pA input current. A high gain stabilization loop is used to periodically cancel the buffer’s offset. The loop itself is periodically disconnected from the buffer and auto-zeroed, during which its bandwidth is reduced to reduce the associated noise folding. However, this also reduces its offset correction range, and so to avoid overloading, its initial offset is digitally trimmed. To break up the correlation between the residual low-frequency (LF) noise of the auto-zero and stabilization phases, the loop is periodically chopped, which significantly reduces the buffer’s LF noise. Finally, the duty-cycle of the two phases is optimized to bring the buffer’s LF noise density close to 2–√ times its white noise density (14 nV/ Hz−−−√ ), which is the fundamental limit of an AZ amplifier. The buffer also achieves a constant and low input current (0.8 pA), as well as a state-of-the-art offset (0.4 μV ).Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
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