937 research outputs found
Indeks Penulis Volume 3 Tahun 2016
No full textIndeks Penulis Mimbar Sekolah Dasar Volume 3 Tahun 201
Indeks Penulis Volume 2 Tahun 2015
No full textIndeks Penulis Mimbar Sekolah Dasar Volume 2 Tahun 201
Giving Dentistry a Hand: Occupational Therapy MSD Prevention in Dentistry
No full textMusculoskeletal disorders (MSDs) pose a significant threat to the dental profession. There are many risk factors inherent in the tasks of dental professionals that could lead to MSDs. A literature review from professional literature, journal articles, and professional websites was used to determine the various risk factors and types of MSDs that occur in the dental profession; best practices in MSD prevention in the dental field; and the role of occupational therapy ergonomic intervention in the dental field. The information has a solid foundation in Malcolm Knowles\u27 theory of Andragogy.
To gather real life information, visits to a dental office were completed by the author, an occupational therapist. A job analysis was conducted with a dentist and other dental professionals were observed and questioned regarding their knowledge of ergonomics. Based upon the compilation of information obtained from all sources Giving Dentistry a Hand: Occupational Therapy MSD Prevention in Dentistry was developed.
Primary risk factors identified include 1) awkward positioning that dental professional use to see within the oral cavity of clients; 2) static sitting postures for most work tasks; and 3) fine, repetitive movements that require a constant pinch and force while holding small tools. The limited quantity and quality of ergonomic education, by qualified ergonomic trainers, during the initial schooling of dental professionals was identified as a primary concern. Best practices for MSD prevention in the dental field include ergonomic evaluations, stretching programs, and ergonomic education. Occupational therapists have the skills and experience for successful intervention in the prevention of MSDs in the dental profession. Giving Dentistry a Hand: Occupational Therapy MSD Prevention in Dentistry is a tool that occupational therapists can use to educate themselves on job-related issues of the dental profession and plan an outstanding professional development workshop that focuses on key issues in the dental profession. This product consists of an educational article and a professional development workshop. Both the article and the professional development workshop are intended to be implemented by occupational therapists who are interested in preventing musculoskeletal disorders within the dental profession
A review on the association between computer mouse design and Musculoskeletal Disorders (MSD)
No full textProlonged mouse usage is one of the main causes of computer-related musculoskeletal disorders (MSD). Mouse is one of the most common input devices to be paired with a computer. Mouse is used to point, select and click across a computer screen with minimal effort. Nevertheless, computer mouse usage has been associated with musculoskeletal disorders. Because of that, mouse designs with ergonomic characteristics and features have been designed and marketed. This review aims to list the different types of mouse designs reported in the literature, and explore the association between mouse design and musculoskeletal
disorders. To achieve the objectives, a systematic search was conducted on five online databases: PubMed, Science Direct, Cochrane Library, Biomed Central and Directory of Open Access Journals (DOAJ), as well as Google search engine using several keywords. Out of 7,131 hits, 13 papers were selected for this review after undergoing multiple stages of the paper selection process. Data were then extracted and summarised into a table according to the following characteristics: 1) Title, 2) Author, 3) Year, 4) Participant, 5) Mouse design, 6) Outcome measure, 7) Findings, and 8) Association between mouse design and MSD. This review found six
different types of mouse designs, all of which were reportedly better than a conventional mouse in maintaining natural posture and reducing muscle activity. Therefore, it can be concluded that there is an association between computer mouse design and musculoskeletal disorder
Design for additive manufacturing of decoupled compliant mechanisms: With an example of a monolithic adjustable mount
No full textMechanical Engineering | Mechatronic System Design (MSD
Augmented Fractional-order Reset Control: Application in Precision Mechatronics
No full textMechanical Engineering | Mechatronic System Design (MSD
Clinical Presentation and Outcome of COVID-19 in a Latin American Versus Spanish Population: Matched Case-Control Study
No full textPublisher Copyright: © 2022, The Author(s).Introduction: Increased mortality has been reported in the Latin American population. The objective is to compare the clinical characteristics and outcome of Latin American and Spanish populations in a cohort of patients hospitalized with COVID-19 during the first year of the pandemic. Methods: We retrospectively analysed all the Latin American patients (born in South or Central America) hospitalized in our centre from February 2020 to February 2021 and compared them with an age- and gender-matched group of Spanish subjects. Variables included were demographics, co-morbidities, clinical and analytical parameters at admission and treatment received. The primary outcomes were ICU admission and mortality at 60 days. A conditional regression analysis was performed to evaluate the independent baseline predictors of both outcomes. Results: From the 3216 patients in the whole cohort, 216 pairs of case-controls (Latin American and Spanish patients, respectively) with same age and gender were analysed. COPD was more frequent in the Spanish group, while HIV was more prevalent in the Latin American group. Other co-morbidities showed no significant difference. Both groups presented with similar numbers of days from symptom onset, but the Latin American population had a higher respiratory rate (21 vs. 20 bpm, P = 0.041), CRP (9.13 vs. 6.22 mg/dl, P = 0.001), ferritin (571 vs. 383 ng/ml, P = 0.012) and procalcitonin (0.10 vs. 0.07 ng/ml, P = 0.020) at admission and lower cycle threshold of PCR (27 vs. 28.8, P = 0.045). While ICU admission and IVM were higher in the Latin American group (17.1% vs. 13% and 9.7% vs. 5.1%, respectively), this was not statistically significant. Latin American patients received remdesivir and anti-inflammatory therapies more often, and no difference in the 60-day mortality rate was found (3.2% for both groups). Conclusion: Latin American patients with COVID-19 have more severe disease than Spanish patients, requiring ICU admission, antiviral and anti-inflammatory therapies more frequently. However, the mortality rate was similar in both groups.This work was financed by ad hoc patronage funds for research on COVID-19 from donations from citizens and organizations to the Hospital Clínic de Barcelona-Fundació Clínic per a la Recerca Biomèdica, Barcelona, Spain. No funding or sponsorship was received for the publication of this article. All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published. Rodrigo Alonso and Ana M. Camon both were responsible for reviewing the data, and they prepared the database including the matching analysis as well as a first draft of the article. Celia Cardozo, Laia Albiach, Daiana Agüero, M. Angeles Marcos, Juan Ambrosioni, Marta Bodro, Mariana Chumbita, Lorena de la Mora, Nicole Garcia-Pouton, Gerard Dueñas, Marta Hernandez-Meneses, Alexy Inciarte, Genoveva Cuesta, Fernanda Meira, and Laura Morata made significant contributions to the manuscript. Pedro Puerta-Accalde, Sabina Herrera, and Gemma Sanjuan performed the statistical analysis and made significant contributions to the final manuscript. Montse Tuset, Pedro Castro, Sergio Prieto-Gonzalez, Josep Mensa, and José Antonio Martínez collaborated on the design of the study and critically reviewed the article. J.M. Nicolas, A. Del Rio, Jordi Vila, Felipe Garcia, Carolina Garcia-Vidal, and Alex Soriano were responsible for the design of the study and made significant contributions to the final version of the article. Alex Soriano, as the corresponding author, answered the reviewers' questions. Hospital Clinic of Barcelona COVID-19 Research Group: Infectious Diseases’ Research Group : J. L. Blanco, J. Mallolas, E. Martínez, M. Martínez, J. M. Miró, A. Moreno, M. Solá, A. Ugarte, Ana Gonzalez-Cordón, Montse Laguno, Lorna Leal, John Rojas, Berta Torres, and all the staff members. Medical Intensive Care Unit : S. Fernandez, A. Tellez, F. Fuentes, E. Sancho, M. Ayala. Department of International Health : D. Campubri, M. T. de Alba, M. Fernandez, E. Ferrer, B. Grau, H. Marti, M. Muelas, M. J. Pinazo, N. Rodriguez, M. Roldan, C. Subira, I. Vera, N. Williams, A. Almuedo-Riera, J. Muñoz, and all the staff members. Department of Internal Medicine : A. Aldea, M. Camafort, J. Calvo, A. Capdevila, F. Cardellach, I. Carbonell, E. Coloma, A. Foncillas, R. Estruch, M. Feliu, J. Fernández-Solá, I. Fuertes, C. Gabara, I. Grafia, A. Ladino, R. López-Alfaro, A. López-Soto, I. Macaya, F. Masanés, A. Matas, M. Navarro, J. Marco-Hernández, L. Miguel, J. C. Milisenda, P. Moreno, J. Naval, D. Nicolás, H. Oberoi, J. Padrosa, S. Prieto-González, M. Pellicé, J. Ribot, O. Rodríguez-Núnez, E. Sacanella, F. Seguí, C. Sierra, A. Tomé, M. Torres, H. Ventosa, C. Zamora-Martínez, and all the staff members. Department of Microbiology : M. Almela, M. Alvarez, J. Bosch, J. Costa, G. Cuesta, B. Fidalgo, J. Gonzàlez, F. Marco, S. Narvaez, C. Pitart, E. Rubio, A. Vergara, M. E. Valls, Y. Zboromyrska and all the staff members. Department of Farmacy : E. López, and all the staff members. Carol García-Vidal has received honoraria for talks on behalf of Gilead Science, MSD, Novartis, Pfizer, Jannsen, and Lilly, as well as a grant from Gilead Science and MSD. Laura Morata has received honoraria for talks on behalf of Merck Sharp and Dohme, Pfizer and Angelini. Pedro Puerta-Alcalde has received honoraria for talks on behalf of Gilead Science and MSD. Montse Tuset has received grants from Janssen, Gilead, ViiV and Merck Sharp and Dohme. Josep Mensa has received honoraria for talks on behalf of Merck Sharp and Dohme, Pfizer, Novartis and Angelini. Álex Soriano has received honoraria for talks on behalf of Merck Sharp and Dohme, Pfizer, Novartis, Gilead, Menarini and Angelini as well as grant support from Pfizer and Gilead. Rodrigo Alonso, Ana M Camón, Celia Cardozo, Laia Albiach, Daiana Agüero, M Ángeles Marcos, Juan Ambrosioni, Marta Bodro, Mariana Chumbita, Lorena de la Mora, Nicole García-Pouton, Gerard Dueñas, Marta Hernández-Meneses, Alexy Inciarte, Genoveva Cuesta, Fernanda Meira, Sabina Herrera, Pedro Castro, Sergio Prieto-González, Jose Antonio Martínez, Gemma Sanjuan, Josep María Nicolás, Ana del Río, Jordi Vila and Felipe García have nothing to disclose. The Institutional Ethics Committee of Hospital Clinic of Barcelona approved the study and, due to the nature of the retrospective data review, waived the need for informed consent from individual patients (HCB/2020/0273). The study was performed in accordance with the Helsinki Declaration of 1964, and its later amendments. The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.Peer reviewe
Column bases in shear and normal force
No full textConnections of steel columns to concrete foundations may be loaded by combinations of normal force, bending moment and shear force. Shear force will primarily be transmitted by friction between the base plate and the grout layer to the concrete foundation. If the compression force is small, or if tension force is present, as may occur in slender high rise structures like towers and masts, the friction will be small or absent. Then, the anchor bolts will be loaded by shear force and bending moment. At the Stevin Laboratory of Delft University of Technology, experimental and theoretical research has been carried out on column bases loaded by combinations of shear force and tension force. In the paper, the main results of this research programme are summarised. The test results and the analytical model that was developed to describe the load deformation behaviour are presented. A comparison is made with the design rules as given by the Comité Euro-International du Béton (CEB, 1994 and 1996). Based on the research, design rules for this load case were proposed to the drafting panel for the revision of Eurocode 3 from ENV to EN status (Part 1.8: Design of Joints)
Inclusion of the Mobility Impaired in our Community: Ask First!
No full textThis DEI Series feature article provides a unique perspective on the inclusion of individuals with physical disabilities, focusing on mobility impairment, in the dental profession and community. The author, a paraplegic orthodontist, shares personal experiences and challenges, shedding light on the importance of considering physical disabilities in dental offices. Navigational difficulties in compliant yet wheelchair-unfriendly spaces are discussed, urging practitioners to have contingency plans. The article emphasizes the significance of etiquette in assisting individuals with disabilities, encouraging respectful communication and asking before offering help. Practical insights on dental chair usage and transfer assistance are provided, promoting a more inclusive environment for both providers and patients
Automatic generation of 3D motifs for classification of protein binding sites
No full textBACKGROUND: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of protein function. Protein 3D structures can be clustered according to their fold or secondary structures to produce classes of some functional significance. A recent alternative has been to detect specific 3D motifs which are often associated to active sites. Unfortunately, there are very few known 3D motifs, which are usually the result of a manual process, compared to the number of sequential motifs already known. In this paper, we report a method to automatically generate 3D motifs of protein structure binding sites based on consensus atom positions and evaluate it on a set of adenine based ligands.
RESULTS: Our new approach was validated by generating automatically 3D patterns for the main adenine based ligands, i.e. AMP, ADP and ATP. Out of the 18 detected patterns, only one, the ADP4 pattern, is not associated with well defined structural patterns. Moreover, most of the patterns could be classified as binding site 3D motifs. Literature research revealed that the ADP4 pattern actually corresponds to structural features which show complex evolutionary links between ligases and transferases. Therefore, all of the generated patterns prove to be meaningful. Each pattern was used to query all PDB proteins which bind either purine based or guanine based ligands, in order to evaluate the classification and annotation properties of the pattern. Overall, our 3D patterns matched 31% of proteins with adenine based ligands and 95.5% of them were classified correctly.
CONCLUSION: A new metric has been introduced allowing the classification of proteins according to the similarity of atomic environment of binding sites, and a methodology has been developed to automatically produce 3D patterns from that classification. A study of proteins binding adenine based ligands showed that these 3D patterns are not only biochemically meaningful, but can be used for protein classification and annotation
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