1,721,144 research outputs found
APPLICATION OF CLUSTER ANALYSIS TO HEMODIALYSIS PATIENTS AFFECTED BY COVID-19: STRATIFICATION ON LONGITUDINAL DATA
Collection of data used to calculate and validate cluster analysis on two populations of hemodialysis patients affected by COVID-19
Further characterisation of Hb Okazaki [b93 (F8) Cys-Arg], a rare hemoglobin variant found in a family from Naples, Italy.
Hb Okazaki [β93(F8)Cys-Arg], was first described in
1984 as unstable hemoglobin variant having high oxygen
affinity but normal phenotype, and appearing by isoelectric focusing of the hemolysate, under the Author's analytical conditions, as a sharp band migrating near to the
position of HbA.
1
We have encountered this variant in the
course of an hemoglobinopathy survey, in three members
of an italian family (from Naples)
Activin/myostatin receptor signaling and vascular calcifications in chronic kidney disease: A "liaison dangereuse"?
Risk factors for kidney diseases and awareness of blood pressure and proteinuria in general population and in high school students: Italian report for World Kidney Days 2012-2013
Ingles
Muscle protein turnover and low-protein diets in patients with chronic kidney disease
Adaptation to a low-protein diet (LPD) involves a reduction in the rate of amino acid (AA) flux and oxidation, leading to more efficient use of dietary AA and reduced ureagenesis. Of note, the concept of 'adaptation' to low-protein intakes has been separated from the concept of 'accommodation', the latter term implying a decrease in protein synthesis, with development of wasting, when dietary protein intake becomes inadequate, i.e. beyond the limits of the adaptive mechanisms. Acidosis, insulin resistance and inflammation are recognized mechanisms that can increase protein degradation and can impair the ability to activate an adaptive response when an LPD is prescribed in a chronic kidney disease (CKD) patient. Current evidence shows that, in the short term, clinically stable patients with CKD Stages 3-5 can efficiently adapt their muscle protein turnover to an LPD containing 0.55-0.6 g protein/kg or a supplemented very-low-protein diet (VLPD) by decreasing muscle protein degradation and increasing the efficiency of muscle protein turnover. Recent long-term randomized clinical trials on supplemented VLPDs in patients with CKD have shown a very good safety profile, suggesting that observations shown by short-term studies on muscle protein turnover can be extrapolated to the long-term period
Kidney Transplantation in a Patient Affected by Sickle Cell Trait: A Case Report and State-of-the-Art Review
Chronic kidney disease (CKD) is a common feature of sickle cell disease (SCD). The awareness of the clinical presentation and renal involvement in patients affected by hemoglobinopathies is greatly needed. Patient management is particularly complex, especially with kidney transplantation. We, therefore, report the case of a 56-year-old patient affected by sickle cell trait who underwent kidney transplantation. This case will underline all the various challenges the nephrologist must face in this clinical setting and their management
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