1,721,016 research outputs found

    Transplantation: can a single criterion determine the use of ECD kidneys?

    No full text
    Kidneys from expanded-criteria donors (ECDs)—the “kidneys that nobody wanted”—started to be used for transplantations more than a decade ago.1 The purpose of using ECD organs was to expand the donor pool to include donors who are over 60 years of age or are considered to have at-risk kidneys because of conditions such as hypertension or because the cause of death was cerebrovascular

    Autosomal Dominant Polycystic Kidney Disease

    No full text
    A 48-year-old man presented for evaluation of the transplantation of a kidney from a living donor. He had a 14-year history of autosomal dominant polycystic kidney disease with progression to end-stage renal disease that required hemodialysis. Initially, transplantation was not possible because his voluminous, bilateral polycystic kidneys did not leave any space in his abdomen (Panel A). He underwent bilateral nephrectomy; the removed kidneys weighed a total of 22 kg (48.4 lb; 21.6% of his total body weight), and the larger right kidney measured 51 cm (Panel B). Three months after the nephrectomy, he underwent successful kidney transplantation from a living related donor. At the 2-year follow-up, the patient had normal kidney function and a serum creatinine level of 1.27 mg per deciliter (112 μmol per liter)
    corecore