197,605 research outputs found

    The Phoenix Mars Landing: An Initial Look

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    This presentation was part of the session : Ongoing and Proposed EDL Technology DevelopmentSixth International Planetary Probe WorkshopNASA's Phoenix Mars Lander will make a landing on Mars on May 25th, 2008. Following on from the overview of the Phoenix entry, descent and landing (EDL) system given at IPPW5, an initial look at the Phoenix landing will be presented, highlighting the salient, high level events that occurred during EDL. Initial EDL flight reconstruction results will be presented, along with a retelling of the flight operations events that occurred on approach to Mars, and during the landing event itself. Note: Given the short time duration between the Phoenix landing and IPPW6, only a presentation will be prepared for the workshop.NAS

    Transmission electron microscopic images show mitochondrial localization is altered in DKO EDL muscle.

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    <p>A) WT EDL B) DKO EDL at 14000X magnification. C) WT and D) DKO at 34000x magnification. The arrows point to the localization of mitochondria (M) which are at the I band on either side of the Z disc in WT, but this tight localization is reduced in the DKO EDL.</p

    Analysis of Temperature-Constrained Ballute Aerocapture for High-Mass Mars Payloads

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    This presentation was part of the session : Ongoing and Proposed EDL Technology DevelopmentSixth International Planetary Probe WorkshopWe investigate trajectories and heating environments of ballute-assisted, low- to high-mass Mars aerocapture systems. Ballutes permit aerocapture at higher altitudes and allow for lower thermal protection system (TPS) mass than traditional aeroshells, due to lower heat fluxes. Trajectory calculations are presented for capture into a 4-day parking orbit about Mars with varying vehicle masses (of 1-100 tons) and with a ballute temperature constraint of 500 degrees C. We note that, for the same ballistic coefficient, a higher mass payload will require a larger ballute and consequently will have a lower ballute temperature (due to a larger nose radius). Compared to a payload of 1 ton (requiring a ballistic coefficient of 0.76 kg/m(2)), a higher ballistic coefficient (of 3.45 kg/m(2)) can be employed for the high mass payload (of 100 tons) while satisfying the temperature constraint, thus allowing for capture of high-mass payloads with smaller ballutes than previously estimated. To substantiate these conclusions, which are based on analytical heating calculations, we conduct a detailed aerothermodynamic analysis at maximum heat flux conditions (for payloads of 1, 10, and 100 tons). We use the Langley Aerothermodynamic Upwind Relaxation Algorithm (LAURA) to analyze the ballute in the continuum flow regime where the Navier-Stokes equations apply.Purdue University ; NASA MSFC ; NASA LRC ; Global Aerospace Corporatio

    The eDL mobile app - Improving communication between hospitals, patients and community physicians

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    Lezcano, L., Drachsler, H., Ternier, S., Kalz, M., & Specht, M. (2012, October). The eDL mobile app - Improving communication between hospitals, patients and community physicians. Presentation at the kickoff meeting of the Patient project, Heerlen, The Netherlands.Presentation of the eDL app, at the kickoff meeting of the PATIENT project.The work in this publication has been sponsored by the Patient Project that has been funded with support from the European Commission. 527620-LLP-1-2012-1-NL-ERASMUS-FEXI. [http://patient-project.eu/

    Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice

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    The membrane electrical properties of diaphragm and extensor digitorum longus (EDL) muscle fibers of dystrophic mdx and control mice from 4 wk to 14-19 mo of age were recorded with the intracellular microelectrode technique. Up to 8 wk of age, the diaphragm and EDL muscles did not differ between the two strains. From 8 up to 20 wk, the mdx diaphragm fibers showed a higher membrane resistance (R(m)), which was due to significantly lower values of resting chloride conductance (G(Cl)) and an overexcitability with respect to age-matched controls. Oppositely, the mdx EDL muscle fibers had significantly lower R(m) and higher G(Cl) values than age-related controls at 8, 10, and 13 wk, along with a decreased membrane excitability. These differences were no longer detectable at 20 wk. The diaphragm and EDL muscles from 14- to 19-mo-old controls showed a decrease of G(Cl) and an increase of potassium conductance with respect to adult animals. In aged mdx animals, these changes were very dramatic in diaphragm fibers, whereas no differences, with respect to adults, were found in the EDL muscle. Thus G(Cl) is an index of the dystrophic condition of mdx muscles. In the degenerating diaphragm, the impairment of G(Cl) can account for some of the pathological features of the muscle. In the EDL muscle, the changes of G(Cl) can follow the high regenerative potential of the hindlimb muscles of the mdx phenotype

    Understanding Concerns about Community Relations in Kirklees

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    This study examined attitudes and dispositions towards greater ethnic and religious diversity, as well as community relations more generally, among residents of predominantly white British neighbourhoods. It also examined people’s attitudes and responses to anti-minority protest by groups like the English Defence League (EDL) and towards cohesion policy and practices. A mixed methods design was used combining a (non-representative) household survey (n=434) in four selected research sites (three areas in north Kirklees, one area in south Kirklees) with six key informant interviews (across key institutions) and fifteen focus group discussions (across age-ranges and localities) with local peopl

    Understanding Concerns about Community Relations in Calderdale

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    •This study examined attitudes and dispositions towards greater ethnic and religious diversity, as well as community relations more generally, among residents of predominantly white British neighbourhoods. It also examined people’s attitudes and responses to anti-minority protest by groups like the English Defence League (EDL)and towards cohesion policy and practices. A mixed methods design was used combining a (non-representative) household survey (n=212) in three selected research sites (Illingworth, Sowerby Bridge and Todmorden) with eight key informant interviews (across key institutions) and nine focus group discussions (across age-ranges and localities) with local people

    Body weight and EDL weight analysis.

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    <p>A: Body weight was significantly reduced in presence of Prednisolone. B: EDL weight showed a similar pattern to body weight. C: Body weight and EDL weight show a close correlation. D: Total EDL force/BW shows a similar ratio in all groups, with a non-significant (P = 0.09) trend to be lower in untreated <i>mdx</i> mice. C57BL/10, n = 4–8; U: untreated <i>mdx</i> mice, n = 6, P: Prednisolone treated <i>mdx</i> mice, n = 10, LS: Lisinopril-Spironolactone treated <i>mdx</i> mice, n = 10; LSP, Lisinopril-Spironolactone-Prednisolone treated <i>mdx</i> mice n = 6; TS: Losartan-Spironolactone treated <i>mdx</i> mice, n = 11; TSP: Losartan-Spironolactone-Prednisolone treated <i>mdx</i> mice, n = 8. * indicates a significantly lower value compared to the equivalent primary treatment without Prednisolone, P<0.05.</p

    EDL and soleus muscle force vs. frequency relationships.

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    Muscle contraction was stimulated with increasing frequencies from 1–130 Hz to determine the force-frequency relationship. A) EDL muscle absolute force. Inset: Raw data traces of 1 Hz, 20 Hz and maximal tetanic contractions (* denotes Pβ-alanine compared to control diet; a denotes Pβ-alanine compared to control diet). B) EDL muscle specific force (* denotes Pβ-alanine compared to control diet). C) Soleus muscle absolute force. D) Soleus muscle specific force. (EDL: Control-n = 24 muscles, HMB-n = 23 muscles, β-alanine-n = 24 muscles, HMB + β-alanine-n = 24 muscles. SOL: Control-n = 23 muscles, HMB-n = 24 muscles, β-alanine-n = 24 muscles, HMB + β-alanine-n = 24 muscles).</p
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