4,664 research outputs found
Draper, E T, QX5752
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/382631Surname: DRAPER. Given Name(s) or Initials: E T. Military Service Number or Last Known Location: QX5752. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 22017.213900
Item: [2016.0049.14924] "Draper, E T, QX5752
Temporal changes in pipeline-seabed condition, and their effect on operating behaviour
It is increasingly recognized that the state of the seabed surrounding an on-bottom pipeline may change during the operating life of the pipeline. For seabed sediments that are soft and fine-grained, the strength may vary through episodes of pipeline movement due to consolidation effects. For seabed sediments that are mobile due to waves and currents, the burial state and the adjacent seabed topography may vary due to sediment transport and scour. These changes in the strength and topography of the surrounding seabed alter the exposure of the pipeline to hydrodynamic loads and ambient cooling, as well as the level of geotechnical support and insulation provided by the seabed. The design relevance of these changes in seabed condition is amplified by modern design approaches in which the pipeline itself can be tolerably mobile-for example in a dynamic onbottom stability approach or through engineered schemes of global buckling and axial walking. This paper illustrates the interactions between the geotechnical and sediment transport processes and the resulting global pipeline behaviour. Two interactions are considered: the long-term axial walking behaviour on soft soil, and the longterm insulation and temperature profile on a mobile seabed. The examples highlight the potential for over or underestimation of various inputs to a pipeline design when these temporal changes in pipe-seabed condition are overlooked. Emerging analysis methods for pipeline-seabed interaction that incorporate these temporal effects can lead to more reliable and cost-effective design.</p
Effect of sediment supply on suction scour under a rock berm
This paper presents a case study of sediment transport behaviour from between armor rocks in a rock berm placed on a fine sandy seabed model. The test was conducted in the Large O-tube facility at The University ofWestern Australia under steady current and combined irregular flow conditions (live bed). Suction removal of sediment from under the rocks has been identified as a mechanism that can lead to the sinkage of a berm by previous researchers. Suction removal was not observed in the reported tests. Instead the gaps between rocks were filled up gradually with sand. The main reason for this contrasting behaviour compared to previous studies was that there was sediment supply from upstream, thanks to the recirculating nature of the O-tube flume. This supply added sediment to the rock berm in excess of that which could be mobilised through suction scour. This result suggests that the influence of sediment supply should be considered to create improved physical modelling of suction scour, and to allow better design of rock berms for stability against sinking.</p
Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper
SummaryNeuronal injury triggers robust responses from glial cells, including altered gene expression and enhanced phagocytic activity to ensure prompt removal of damaged neurons. The molecular underpinnings of glial responses to trauma remain unclear. Here, we find that the evolutionarily conserved insulin-like signaling (ILS) pathway promotes glial phagocytic clearance of degenerating axons in adult Drosophila. We find that the insulin-like receptor (InR) and downstream effector Akt1 are acutely activated in local ensheathing glia after axotomy and are required for proper clearance of axonal debris. InR/Akt1 activity, it is also essential for injury-induced activation of STAT92E and its transcriptional target draper, which encodes a conserved receptor essential for glial engulfment of degenerating axons. Increasing Draper levels in adult glia partially rescues delayed clearance of severed axons in glial InR-inhibited flies. We propose that ILS functions as a key post-injury communication relay to activate glial responses, including phagocytic activity
Image-based approach for calculating sediment transport rate and estimating seabed shear stress during scour
In this paper an imaged-based approach is presented for calculating the sediment transport rate and estimating the seabed shear stress regularly in space and time during a model scale experiment involving scour. The approach works by solving the inverse form of the sediment continuity equation to determine the transport rate in terms of the seabed elevation using concurrent images recorded by a digital video camera. The calculated transport rate is then converted into an estimate of the seabed shear stress by (i) defining a functional relationship between the volumetric transport rate and shear stress, and (ii) estimating the free field shear stress. In this way the shear stress can be estimated without the need for any other form of measurement. Application of the approach requires that scour is confined to one plane (i.e. 2D) and that sediment transport is uni-modal (i.e. transport is via bedload or erosion only) and occurs at every point along the seabed. To demonstrate the new technique we present an example application to fixed pipelines located at different distances above a sand bed subjected to steady current. Results are in reasonable agreement with numerical models and indirect measurements of seabed shear stress.</p
Socioeconomic inequalities in very preterm birth rates
Aims: To investigate the extent of socioeconomic inequalities in the incidence of very preterm birth over the past decade. Methods: Ecological study of all 549 618 births in the former Trent health region, UK, from 1 January 1994 to 31 December 2003. All singleton births of 22+0 to 32+6 weeks gestation (7 185 births) were identified from population surveys of neonatal services and stillbirths. Poisson regression was used to calculate incidence of very preterm birth (22-32 weeks) and extremely preterm birth (22-28 weeks) by year of birth and decile of deprivation (child poverty section of the Index of Multiple Deprivation). Results: Incidence of very preterm singleton birth rose from 11.9 per 1000 births in 1994 to 13.7 per 1000 births in 2003. Those from the most deprived decile were at nearly twice the risk of very preterm birth compared with those from the least deprived decile, with 16.4 per 1000 births in the most deprived decile compared with 8.5 per 1000 births in the least deprived decile (incidence rate ratio 1.94; 95% CI (1.73 to 2.17)). This deprivation gap remained unchanged throughout the 10-year period. The magnitude of socioeconomic inequalities was the same for extremely preterm births (22-28 weeks incidence rate ratio 1.94; 95% CI (1.62 to 2.32)). Conclusions: This large, unique dataset of very preterm births shows wide socio-economic inequalities that persist over time. These findings are likely to have consequences on the burden of long-term morbidity. Our research can assist future healthcare planning, the monitoring of socio-economic inequalities and the targeting of interventions in order to reduce this persistent deprivation gap.</p
PANIC by S. Draper
Draper, Sharon M. PANIC. New York: Atheneum Books for Young Readers, 2013. Print.Imagine ... waking up, tied to a bed, groggy, naked, and alone. What would you do?PANIC is a gripping tale of two teenage girls and their experience with manipulation, abduction, and abuse. After meeting Thane, the handsome Hollywood movie director, 15-year-old Diamond is easily persuaded to accompany him back to his family\u27s home to audition for an exciting part in upcoming movie. It\u27s a dream come true for the aspiring dancer! Diamond ignores everything she\u27s been taught since she was a little girl, and willingly gets into a car with the stranger. Still unaware of the looming danger, Diamond is lured into Thane\u27s house, accepts a drink, and then pays the unthinkable price for the promise of starring in a Hollywood movie. She is now being held captive and forced to "play her part" in Thane\u27s horrifying production, all while her family and friends, who are desperately waiting for news of her safety, live through their own horrors and traumas. While each girl fights for escape from their own personal prison, they desperately search for an inner strength they hope is there. From the award-winning, New York Times bestselling author, Sharon M. Draper, this is a heart-breaking story that quickly turns into an exhilarating examination of power and loss, and the inspiring fight to take it all back.Sharon M. Draper\u27s PANIC is a heart-pounding saga that will easily appeal to a wide age and range of readers. Defined as hi-lo contemporary fiction, it is a novel originally written for a young adult audience, and is a story that addresses important issues like abduction, sexual abuse, and bullying. It is a book that teaches valuable lessons, and so, may also appeal to parents and caregivers, and act as an important discussion piece for families. While offering insightful symbolism and the opportunity to dig deep into heavy themes (like the objectification of women and abusive teen relationships), it will work well for strong and inquisitive readers, however, with its short chapters, sobering plot, and strong young characters, this novel will attract many reluctant readers who are looking for a quick yet interesting read. Although the action is intense, emotional, and distressing at times the ease of dialogue and growth of the characters draws the reader in and forces them to think about their own risky behaviour, and the potential for resulting danger. Be aware that the trivial language used too often by the young characters can become tedious and annoying, and with a religious element to the book, some readers may feel uncomfortable at certain points. Yet, it is Draper\u27s ability to so vividly capture the mind and heart of the adolescent, and the important and powerful life lessons the story delivers, that makes PANIC a must-have addition to any collection.Highly Recommended: 4 out of 4 StarsReviewer: Kimberley K. MortonKim Morton is a secondary History teacher and Learning Coordinator with the Saskatoon Public School Division. She is currently working toward her Masters of Education, specializing in Teacher-Librarianship, through the University of Alberta. She strives to make research and inquiry meaningful, relevant, and fun for her students, and is looking to gain more experience with current technology, trends, and tools. She enjoys sports, is an avid reader of historical novels, and loves going to the movies
Alignment between chronic disease policy and practice : case study at a primary care facility
Includes bibliographical references.Current literature supports the need to make the prevention and management of chronic diseases an international health priority. In South Africa, our Health Minister has committed the government to tackling the burden of chronic diseases alongside communicable diseases. The Western Cape has developed an excellent policy and framework to guide and improve the prevention and management of chronic diseases at a primary care level, however limited literature exists around the alignment of the policy with current practice and around any challenges to its implementation. Should the policy be well implemented, it has the potential to make a significant difference to the health of the population served. For this reason, the overall purpose of this study is to improve the care and management of patients with chronic diseases within primary health care facilities. The aim of this study is to assess the alignment of current primary care practices with the PGWC Adult Chronic Disease Management policy (which includes an audit tool), using one primary health care facility in the Cape Town metropolis as a case study
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