88 research outputs found

    Three-dimensional echocardiographic evaluation of right ventricular volume and function in pediatric patients: Validation of the technique

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    J Am Soc Echocardiogr. 2007 Aug;20(8):921-9. Epub 2007 Jun 6. Three-dimensional echocardiographic evaluation of right ventricular volume and function in pediatric patients: validation of the technique. Grison A, Maschietto N, Reffo E, Stellin G, Padalino M, Vida V, Milanesi O. Source Department of Pediatrics, University of Padova, School of Medicine, Padova, Italy. Abstract The right ventricle (RV) is the main ventricular chamber in many congenital heart diseases before and after surgical correction, and it is the most important determinant of outcome in postoperative tetralogy of Fallot and other complex malformations. Unfortunately its irregular crescentic shape does not allow the use of the geometric assumption used for the left ventricle. Many methods have been suggested in the literature to overcome this problem, none fully reliable. The introduction of volume-rendered 3-dimensional (3D) reconstruction of echocardiography images provides a tool for the direct measurement of cardiac chambers, not based on geometric assumptions. The aim of this research study was to determine the accuracy of 3D echocardiography (3DE) to measure RV volumes in pediatric patients with secundum atrial septal defects, compared with direct volume measurements performed during the intervention. We performed 3DE study in the operating department, with the patient anesthetized, intubated, and ventilated before the surgical procedure. Sequential 2-dimensional echocardiographic images for subsequent 3D rendering were acquired using an ultrasound machine with a transthoracic 4-MHz rotational or 5-MHz transesophageal omniplane probe; in the last 5 patients a machine was used that was equipped with a 3600-crystal real-time 3D probe. To validate the 3DE measurements, these were compared with the volume of the RV directly measured in the operating department, at the end of the surgical procedure, injecting saline solution through the tricuspid valve, using a graduate syringe. Among 25 pediatric patients enrolled in the study, with an age range of 1 and 14 years (mean 4 years) and a weight range of 8.5 to 57.4 kg (mean 18.6 kg), in 23 a mean of 3 echocardiographic acquisitions were performed and compared with the direct measurement. A close comparison was found between RV volumes measured by 3DE and direct volume measurements (P < .00001). The regression line, shifted toward the y axis, which describes the 3DE volumes, indicated that the echocardiographic measures overestimate the surgical ones. In our study this overestimation had the mean of 9% with values comprised between 3% and 19%. The coefficient of repeatability was 4.79 mL with all the values within this range (2 SD of the mean). We conclude that 3DE provides an accurate measurement of RV volume in pediatric patients with RV volume overload. It is a reliable, noninvasive, and nongeometric method of evaluation of the volume of this chamber, and can be considered a precious tool in the armamentarium of the pediatric cardiologist

    Spazi e pagine che includono : un Parco, un libro = Spaces and pages that include : a Park, a book

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    The 'Treasure Tree Park' will be inaugurated in spring 2024 and will be the first sensory‐inclusive municipal park in Padua: it is a project of the Municipality of Padua and the Robert Hollman Foundation in cooperation with 17 institutions, including the University of Padua. A total of 1528 children from pre‐school and primary schools were involved in the co‐design, using "The Treasure of the Enchanted Labyrinth", a specially written and illustrated book characterised by its being multi‐coded (writing with Easyreading© fonts, in Braille, Alternative augmentative communication ‐ CAA, audiobook) and therefore accessible. On the occasion of the international competition for tactile publishing Typhlo &amp; Tactus (Padua, March 2022), the book was reissued as a TIB (Tactile Illustrated Book), adding tactile illustrations and a translation into LIS (Italian Sign Language) to the previous codes

    Co-progettare un Parco per co-costruire cultura dell'inclusione. Progettare il "Parco DI tutti" di Padova con i bambini della scuola dell'infanzia e primaria

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    Il “Parco DI tutti” sarà il primo parco comunale sensoriale inclusivo di Padova; il suo progetto, tutt’ora in via di realizzazione, è stato promosso dal Comune di Padova e dalla Fondazione Robert Hollman in collaborazione con 16 Enti, fra cui l’Università di Padova. Sin dalla fase ideativa del Progetto, si sono voluti coinvolgere attivamente i bambini delle scuole dell’infanzia e primarie di Padova, in qualità di fruitori abituali di spazi condivisi e anche di consulenti competenti. Per far ciò, è stato realizzato un corso di formazione per rivolto a 108 insegnanti, i quali hanno successivamente coinvolto i 1528 bambini delle loro sezioni e classi in percorsi laboratoriali. Al loro interno, i bambini hanno potuto esprime e lavorare sulle proprie rappresentazioni della disabilità, giungendo a progettare spazi di gioco, relazione e partecipazione accessibili a tutti

    Infantile nystagmus without overt eye abnormality: Early features and neuro‐ophthalmological diagnosis

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    Aim: To analyse the neuro-ophthalmological data of children referred for further work-up of infantile nystagmus where ophthalmological evaluation had not achieved a diagnosis. Method: We retrospectively reviewed medical records of patients presenting with infantile nystagmus at our institution between 2007 and 2019. Inclusion criteria were onset before 6 months of age, availability of complete ophthalmic examination, visual electrophysiological tests, and neurological examination. Children with a previous definite ophthalmological diagnosis at onset and those with uncertain nystagmus onset age were not recruited. Results: Out of 142 infants (mean age at nystagmus onset 3.6 mo, SD 1.7, range 0-6 mo; 56 females, 86 males), 23% had neurological nystagmus, 7% mixed neurological and sensory nystagmus, 48% sensory defect, and 22% idiopathic infantile nystagmus. The neurological diagnoses were inborn errors of metabolism, white matter genetic disorders, and brain malformations. The prevalent diagnosis in the sensory defect subgroup was retinal dystrophy. Interpretation: Infantile nystagmus without diagnostic ocular findings may be due to neurological, retinal, and optic nerve disorders or be a benign idiopathic condition.&nbsp;In infants with and without neurological abnormalities, the search for a sensory defect should include visual electrophysiology performed early in the diagnostic pathway

    Finding 16S rRNA gene-based SNPs for the genetic traceability of commercial species belonging to Gadiformes

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    A SNPs (Single Nucleotide Polymorphism) based analysis was developed to differentiate four economically important species belonging to the Gadiformes order: Pacific cod Gadus macrocephalus, Atlantic cod Gadus morhua, Haddock Melanogrammus aeglefinus and Ling Molva molva. A 430bp fragment of the 16s rRNA gene was amplified using interspecific conserved primer and sequenced. The sequences were aligned and analyzed for the presence of SNPs; three SNPs (MerSNP1, MerSNP7 and MerSNP9) were identified and selected to allow discrimination between the four species. Aplotypes were TCC, CCC, CAT and CAC for Pacific cod, Atlantic cod, Haddock and Ling respectively. Confirmation of results was achieved by sequencing 16s rRNA gene fragments of 16 G. morhua, 7 G. macrocephalus, 15 M. aeglefinus and 5 M. molva samples collected at different fish catching campaign. Nucleotide sequence of 16s rRNA mitochondial gene has been shown to be a useful tool to allow rapid reliable and fully automatable for discrimination of 4 economically important species in fisheries industry

    Flex Picture Ebook: un libro accessibile, un format disponibile

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    I bambini con disabilità spesso non possono accedere al rapporto testo-immagine dei libri illustrati in modo agevole, o possono farlo solo parzialmente, sovente con un notevole sovraccarico sensoriale e/o cognitivo. L’ePub «Leo vuole un pipistrello” consente a ciascun bambino di decidere come accedere al testo e alle immagini, scegliendo se attivare animazioni sonore e visive. Attualmente l’ePub è nella 2^ fase di sperimentazione all’interno del programma Erasmus + “Flex Picture Ebook”, che coinvolge sei partner appartenenti a quattro Paesi Europei: Austria, Francia, Italia e Lituania. Diversamente dai libri digitali, i TIB (tactile illustrated book) non possono venire parametrati sulle esigenze e preferenze dei singoli bambini con deficit visivo: è quindi necessario che essi vengano coinvolti in qualità di tester o meglio di informatori per la messa a punto dei TIB. Questo verrà fatto nella ricerca che vede collaborare il Dipartimento “G.M. Bertin” dell’Università di Bologna e la Fondazione Robert Hollman di Padova, finalizzata alla messa a punto, insieme ai bambini con deficit visivo, di un TIB “editabile”
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