1,721,361 research outputs found
The PORTO study and the gestational age perspective of Doppler interrogation of IUGR fetuses
No full textComment in
Reply: To PMID 23999424. Unterscheider J, Malone FD. Am J Obstet Gynecol. 2014 Sep; 211(3):315-6. Epub 2014 May 1.
Comment on:
Predictable progressive Doppler deterioration in IUGR: does it really exist? Unterscheider J, Daly S, Geary MP, Kennelly MM, McAuliffe FM, O'Donoghue K, Hunter A, Morrison JJ, Burke G, Dicker P, et al.
Am J Obstet Gynecol. 2013 Dec; 209(6):539.e1-7. Epub 2013 Aug 30
Measurement of venous blood flow in the human fetus : a dream comes true, but now for some standardization
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Investigating abnormal bleeding on HRT or tamoxifen : the role of ultrasonography
No full textIn western countries hormone replacement therapy (HRT) is a widely used therapeutic and/or preventive medication in post-menopausal women. Its impact on the endometrium has been extensively investigated. The critical issue is whether and how to monitor the endometrium in women who are taking HRT. Transvaginal ultrasound is a potential candidate for this role. Evidence for the efficiency of transvaginal sonography (TVS) in this context is limited. The criteria used to define a normal or abnormal result in women taking HRT are based largely on data from post-menopausal women who are not taking this treatment. This extrapolation is probably reasonable as long as some degree of caution is used. The use of normative data from post-menopausal women for those taking selective oestrogen receptor modulators (SORMs) is not advised and should be utilized only in the context of research studies as insufficient data exist on which to base cut-off values to discriminate between normal and abnormal endometria
Re: First-trimester screening for pre-eclampsia: Moving from personalized risk prediction to prevention
Full text link3 simple diagnostic criteria (color of the cut tissue, vascularization, and sensitive innervation)
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The impact of HRT on endometrial thickness—do cut‐off values exist?
No full textPurpose
To assess the reference standards for endometrial thickness in patients in Hormonal Replacement Therapy according to the different regimens of therapy.
Methods
Eight centres participated in this study. Main criteria for inclusion in this study were a) at least nine months from menopause and b) at least six months of HRT. Bi-endometrial thickness was measured by transvaginal ultrasound (tvs) in patients on sequential or combined HRT regimens. Women following sequential regimen underwent TVS examination immediately after the withdrawal bleeding, always between 5 and 10 days from the last progesterone tablet. Hysteroscopy and biopsy were performed within 5 days from TVS in all patients with an endometrial thickness > 4.5 mm.
Results
589 patients met the entry criteria. Mean years of HRT treatment were 3.2 ± 2.2. In patients undergoing sequential HRT and combined HRT the mean (± sd) endometrial thickness were 3.5 ± 1.2 mm and 3.6 ± 2 mm. An endometrium > 4.5 mm was observed in 121 patients (20.5%). Hyperplasia, polyps and endocavitary fibroids were found in 15%, 24% and 8% of cases respectively. The positive predictive value of TVS examination was 47%. Endometrial thickness was the only variable significantly and independently associated to histologic abnormalities and endocavitary fibroids.
Conclusions
Sonographic endometrial thickness of 4.5 mm, provides a sensitive tool to select HRT patients who might benefit from hysteroscopy and biopsy
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