129 research outputs found

    Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation

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    Atrial fibrillation (AF) is the most common arrhythmia in clinical practise and its prevalence is increasing. Over the last 25 years, flecainide has been used extensively worldwide, and its capacity to reduce AF symptoms and provide long-term restoration of sinus rhythm (SR) has been well documented. The increased mortality seen in patients treated with flecainide in the Cardiac Arrhythmia Suppression Trial (CAST) study, published in 1991, still deters many clinicians from using flecainide, denying many new AF patients a valuable treatment option. There is now a body of evidence that clearly demonstrates that flecainide has a favourable safety profile in AF patients without significant left ventricular disease or coronary heart disease. As a result of this evidence, flecainide is now recommended as one of the first-line treatment options for restoring and maintaining SR in patients with AF under current treatment guidelines. The objective of this article is to review the literature pertaining to the pharmacological characteristics, safety and efficacy of flecainide, and to place this drug in the context of current therapeutic management strategies for AF

    Emerging curriculum for industry and human applications in Internet of Things

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    \ua9 2017 IEEE. The need of new curricula in the Internet of things (IoT) for MSc, PhD and engineering levels of education is described. The joint project on curricula development ALIOT, financed in the frame of Erasmus+ program, is discussed. The project ensures adaptation of academic programs in Ukraine and other countries to the needs of the labor market in the EU, thus influencing on the expansion of the opportunities for economic and labor diversity. The ALIOT covers hot domains of IoT applications such as health systems, intellectual transport systems, ecology and industry 4.0 systems, smart grid, smart buildings and city. The description of interdisciplinary multi-domain and transnational program of MSc and PhD levels is introduced with the mechanisms of intensive capacity building measures as well as the establishment of multi-domain IoT cluster network (MDICN) in Ukraine is given

    Task Force on Sudden Cardiac Death of the European Society of Cardiology

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    The European Society of Cardiology has convened a Task Force on Sudden Cardiac Death in order to provide a comprehensive, educational document on this important topic. The main document has been published in the European Heart Journal in August 2001. The Task Force has now summarized the most important clinical issues on sudden cardiac death and provided tables with recommendations for risk stratification and for prophylaxis of sudden cardiac death. The present recommendations are specifically intended to encourage the development and revision of national guidelines on prevention of sudden cardiac death. The common challenge for cardiologists, physicians of other medical specialties and health professionals throughout Europe is to realize the potential for sudden cardiac death prevention and to contribute to public health efforts to reduce its burden
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