1,721,042 research outputs found

    Secondo contributo alla flora vascolare dell’Umbria (Italia centrale).

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    In this work 13 new floristic records for Umbria region (central Italy) are reported. The survey was carried out from 2009 to 2015. Some species are of particular interest from a phytogeographical or conservational point of view

    Thyrotropin stimulates production of procoagulant and vasodilatative factors in human aortic endothelial cells

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    Thyroid diseases have been associated with pathophysiological changes in the vasculature that may result from altered thyroid hormone production or to direct effect of elevated thyrotropin (TSH) levels on smooth muscle cells. A direct effect of TSH on vascular endothelium has not been considered. In the present study a strain of human aortic endothelial cells has been stimulated with TSH, and vascular parameters correlated with the atherosclerotic process have been analyzed. Addition of TSH induced an increase of cyclic AMP (cAMP) concentration in human aortic endothelial cells. Furthermore it induced a decrease of endothelin (from 30 +/- 2.5 to 13 +/- 1 fmol/mL) and of tissue plasminogen activator secretion (from 2,800 +/- 200 to 1,600 +/- 150 ng/mL). On the other hand, it increased nitric oxide (from 148 +/- 8 to 211 +/- 12 muM). TSH did not affect plasminogen activator inhibitor 1. Similar results were obtained when immunoglobulin Gs (IgGs) from Graves' disease patients were used. In conclusion, our findings suggest that TSH and IgGs from Graves' disease patients could stimulate endothelial cells, increasing the secretion of procoagulant and vasodilatative factors, and that cAMP is involved in the transduction pathway. These findings are consistent with modifications of the fibrinolytic system reported in hypothyroidism and in Graves' disease. On the other hand, the increase of vascular resistance found in patients with hypothyroidism may be due to the altered thyroid hormone production and not to TSH directly, or to a different effect of TSH on peripheral vessels

    Wild Finnish Truffles

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    Truffle ascocarps were collected from a natural forest located in Lahti, Finland (100 km north to Helsinki ) by the help of a trained truffle dog called Siro in Autuman 2006 . By morphological identification , the truffles were identified as Tuber maculatum and Tuber scruposum . The truffle ascocarps were found in soil with relatively high pH value in coniferous forest . Our studies showed that both tuber species prefer the mixed forest with host- trees such as spruce and pine . Samples of the truffle fruit bodies are conserved in the collection of biological materials in the Juva Truffle Center . Further investigatio concerning truffle species (DNA) and soil properties will be performed in the coming seasons

    Nuovi dati distributivi per il genere Gagea (Liliaceae) in Umbria, Marche e Lazio [New distribution data on the genus Gagea (Liliaceae) in Umbria, Marche e Lazio (Central Italy)]

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    New distribution data on the genus Gagea (Liliaceae) in Umbria, Marche e Lazio (Central Italy). After years of extensive field research, new localities in Umbria, Marche and Latium are reported for eight species of the genus Gagea: G. bohemica (Zauschn.) Schult. & Schult.f., G. fragifera (Vill.) Ehr.Bayer & G.López, G. granatellii (Parl.) Parl., G. lutea (L.) Ker Gawl., G. minima (L.) Ker Gawl., G. pratensis (Pers.) Dumort., G. tisoniana Peruzzi, Bartolucci, Frignani & Minut., G. villosa (M.Bieb.) Sweet
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