209 research outputs found
Huntsville Times sleeve HT0003559
No full textCleve Maxfield, Madison electronics author, with vintage computers. / 122 Fox Hollow Drive, Madiso
The New Book of Chronicles in Eight Chapters [Compiled by the Dexter Correspondent James Dwight Maxfield of The Newport Times ]
No full textA parody of Maine politics circa 1879, written in the form of a chapter of the Bible, recounting the contentious four candidate1879 Maine gubernatorial race. A huge cast of characters and political parties are present. King Gasslon clearly refers to the Governor of Maine from 1879 to 1880 Alonzo Garcelon. Garcelon oversaw the Greenback controversy, when he investigated alleged voter fraud and determined that the Democrats and not the Republicans had won a majority in the legislature. Senator James Blaine arrived at the Capitol in Augusta with a hundred armed men to protest the results, and Garcelon called out the state militia. Intervervention by a group lead by Joshua Chamberlain helped to restore order. Garcelon\u27s term as Governor ended less than two months later.
The incident was profiled in the books Ballot Battles by Edward B. Foley, and Joshua Chamberlain: The Soldier and the Man by Edward Longacre. It was also detailed in a November 2020 article from Downeast Magazine by Brian Kevin called (online) What Happened When a Maine Governor Tried to Rig an Election and (in print) A Governor Tries to Steal an Election.
James Dwight Maxfield, the author, served on the staff of Daniel F. Davis, the winner of the race, and rightful successor to Garcelon [Source: September 16, 1884, Lewiston Evening Journal ]. The men of Daniel are one of the characters Maxfield references throughout the piece.
A truly interesting semi-first hand, yet satirical, account of a forgotten incident of Maine\u27s political and social history known to many at the time as the Twelve Days that shook Maine.https://digicom.bpl.lib.me.us/books_pubs/1368/thumbnail.jp
Collaborative Statistics Textbook
No full textThis 627-page Collaborative Statistics Textbook was written by Susan L. Dean and Barbara Illowsky and is provided by the Maxfield Foundation. This textbook is intended for introductory statistics classes and focuses on applications of statistical knowledge. Four main concepts are emphasized: thinking statistically, incorporating technology, working collaboratively, and writing thoughtfully. A table of contents and the following chapters are included: Preface; Additional Resources; Author Acknowledgements; Student Welcome Letter; Sampling and Data; Descriptive Statistics; Probability Topics; Discrete Random Variables; Continuous Random Variables; The Normal Distribution; The Central Limit Theorem; Confidence Intervals; Hypothesis Testing: Single Mean and Single Proportion; Hypothesis Testing: Two Means, Paired Data, Two Proportions; The Chi-Square Distribution; Linear Regression and Correlation; F Distribution and ANOVA; Appendix; Tables; Glossary; and Index. Homework, Labs, Practice Exams, Data Sets; Solution Sheets; and Formulas are also included.Â
A Comprehensive Outline of World History [electronic resource].
No full textThis free PDF textbook presents Jack E. Maxfield's "A Comprehensive Outline of World History" as originally organized, chronologically by era and across regions within an era. Each chapter covers a period of historical time (e.g. a century). Sections within chapters describe what was going on in every geographical region of the world; each section provides a reference for that region in the subsequent chapter, i.e. in the next time period. The reader can thus get a snapshot of the entire world at a point in time by reading one chapter, or can follow the history of a region through time by linking to sections in successive chapters.http://florida.theorangegrove.org/og/file/f796f14f-c573-1fcd-1cb1-d2a21d9b32b2/1/WorldHistory.pdfhttp://cnx.org/content/col10595/latest/TextbookJack E. MaxfieldAdobe PDFhttp://www.ogtp-cart.com/product.aspx?ISBN=978161610002511, 12, Community College, Higher EducationExpositiveThis free PDF textbook presents Jack E. Maxfield's "A Comprehensive Outline of World History" as originally organized, chronologically by era and across regions within an era. Each chapter covers a period of historical time (e.g. a century). Sections within chapters describe what was going on in every geographical region of the world; each section provides a reference for that region in the subsequent chapter, i.e. in the next time period. The reader can thus get a snapshot of the entire world at a point in time by reading one chapter, or can follow the history of a region through time by linking to sections in successive chapters.Electronic reproduction.University Press of Florida.Mode of access: Internet
The Midwest Quarterly; Vol. 24 No. 3
No full textin this issue. . .
WILLIAM F. SMITH, JR., reveals the depth of meaning, both for students of the American Indian and for those seeking better to know the human personality, in the historical novel, Seven Arrows. Now Chairman of the English Department at Saginaw Valley State College in Michigan, Smith has published extensively on topics dealing with American Indian literature.
Joining the parliamentary and the presidential types of democratic government, according to WALTERS. G. KOHN, is a new, French model, the presidential prerogative system. Author of many articles on politics in Liechtenstein and the rest of Western Europe, Kohn serves as Professor of Political Science at Illinois State University.
To SANFORD PINSKER, Huckleberry Finn was, like a Modernist poet, one who saw the world clearly, both the light and the dark, while Tom Sawyer viewed only the magic of life. Chairman of the English Department at Franklin and Marshall College in Pennsylvania, Pinsker has published widely and includes among his most recent works Critical Essays on Philip Roth. JACK FLAVIN is a librarian for the Springfield (Mass.) City Library.
GREG KUZMA\u27s latest book of poems is Everyday Life from the Spoon River Poetry Press (Peoria).
THOMAS P. LYNCH, undertaker for the village of Milford, Michigan, near Detroit, spends part of each year on his farm in West Moveen, County Clare, Ireland, near the mouth of the Shannon.
DAVID M. CICOTELLO\u27 s interview with William Kloefkorn helps us inaugurate what we hope can become at least an occasional feature in The Midwest Quarterly. Currently pursuing doctoral studies in English at the University of Nebraska (Lincoln), Cicotello has an interview with William Stafford forthcoming in College Composition and Communication.
CAROL A. MARTIN examines the treatment of Victorian women in the works of two novelists, George Eliot and Elizabeth Gaskell, and finds them both more realistic in their depiction of mothers and daughters than their contemporary male counterparts. Professor of English at Boise State University, Martin has read papers on the novelists treated here and has articles in numerous journals.
JAMES MAXFIELD traces the parallels between the real-life traumas of novelist William Maxwell and their literary manifestations and probes the development of character perceived in Maxwell\u27s early works. Author of critical studies on Midwestern novelists, detective fiction, and film, Maxfield is Professor of English at Whitman College in Washington.
TOM HANSEN teaches at Northern State College in Aberdeen, South Dakota. He has works in current issues of The Metro, Hard Pressed, Stony Hills, and other magazines.
JAMES E. GILBERT is Vice-President for Academic Affairs and Professor of Psychology at Pittsburg State University
Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation
No full textDeficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions. The level of VDR is reduced in lungs of patients with chronic obstructive pulmonary disease (COPD) which led us to hypothesize that deficiency of VDR leads to significant alterations in lung phenotype that are characteristics of COPD/emphysema associated with increased inflammatory response. We found that VDR knock-out (VDR(-/-)) mice had increased influx of inflammatory cells, phospho-acetylation of nuclear factor-kappaB (NF-κB) associated with increased proinflammatory mediators, and up-regulation of matrix metalloproteinases (MMPs) MMP-2, MMP-9, and MMP-12 in the lung. This was associated with emphysema and decline in lung function associated with lymphoid aggregates formation compared to WT mice. These findings suggest that deficiency of VDR in mouse lung can lead to an early onset of emphysema/COPD because of chronic inflammation, immune dysregulation, and lung destruction
Treatment of Niemann-Pick Type C Disease by Histone Deacetylase Inhibitors
No full textNiemann-Pick type C disease (NPC) is a devastating, recessive, inherited disorder that causes accumulation of cholesterol and other lipids in late endosomes and lysosomes. Mutations in 2 genes, NPC1 and NPC2, are responsible for the disease, which affects about 1 in 120,000 live births. About 95 % of patients have mutations in NPC1, a large polytopic membrane protein that is normally found in late endosomes. More than 200 missense mutations in NPC1 have been found in NPC patients. The disease is progressive, typically leading to death before the age of 20 years, although some affected individuals live well into adulthood. The disease affects peripheral organs, including the liver, spleen, and lungs, but the most severe symptoms are associated with neurological disease. There are some palliative treatments that slow progression of NPC disease. Recently, it was found that histone deacetylase (HDAC) inhibitors that are effective against HDACs 1, 2, and 3 can reduce the cholesterol accumulation in fibroblasts derived from NPC patients with mutations in NPC1. One example is vorinostat. As vorinostat is a Food and Drug Administration-approved drug for treatment of cutaneous T-cell lymphoma, this opens up the possibility that HDAC inhibitors could be repurposed for treatment of this rare disease. The mechanism of action of the HDAC inhibitors requires further study, but these drugs increase the level of the NPC1 protein. This may be due to post-translational stabilization of the NPC1 protein, allowing it to be transported out of the endoplasmic reticulum.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000326276300011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Clinical NeurologyNeurosciencesPharmacology & PharmacySCI(E)25REVIEW4688-6971
William Morris and Edward Carpenter: back to the land and the simple life, 1880-1910
No full textThis thesis focuses on the influence of William Morris and Edward Carpenter on
aspects of the back-to-the-land and simple-life movements between the years 1880-
1910. Specifically, it seeks to define and explore the convergence and divergence of
both writers' return-to-nature ideology, and considers their influence on the
development of particular groups, who represented some of the multiplicity of backto-
the-land ideas and experiments current during this period. The thesis is divided
into three main parts; the intellectual framework for the study is broad, and takes into
account the historical context, the cultural significance and the character of the
material in each section.
The first part of the thesis undertakes an expository evaluation of key texts
from Morris's and Carpenter's political journalism, lectures and imaginative writing,
examining how both writers developed an appropriate language to convey their
social and political ideals. The critical method employed uses detailed textual
analysis, identifying and discussing the individual qualities of Morris's and
Carpenter's back-to-the-land writing, and reflecting on the differing emphases of
their utopian rhetoric. The second part of the research explores the take-up of
Morris's and Carpenter's ethos in four diverse and little known late-nineteenthcentury
journals, concerned with simple-life issues and a return to the land, namely
Seed-time, The New Order, Land and Labor and Land and People. It employs the
thinking of Pierre Bourdieu and Mikhail Bakhtin to establish an appropriate balance
between critical theory and empirical study. Lastly using a historical and descriptive
method the thesis uses archival material to examine the nature and extent of both
writers' influence on two Cotswold back-to-the-land experiments - the Whiteway
Colony and the Chipping Campden Guild of Handicraft. These provide a particular
opportunity to consider and compare the practical outcomes of return-to-the-land and
simple-life ideologies.
The study extends scholarship in this area by significantly re-appraising the
relationship between Morris's and Carpenter's back-to-the-land writing, and reinstating
Carpenter as a germinal influence. It also increases our understanding of the
values and function of the journals in the study, and establishes an insight into the
wider cultural assimilation of both writers' ideals
Detecting and mapping the onset stages of soil salting in areas of incipient dryland salinity : an early warning case study from the Warrenbayne - Boho landcare district, north - east Victoria
No full textThis thesis was scanned from the print manuscript for digital preservation and is copyright the author.
Researchers can access this thesis by asking their local university, institution or public library to
make a request on their behalf. Monash staff and postgraduate students can use the link in the References field
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