77 research outputs found
Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in patients after acute myocardial infarction
No full textMasahiko Hara, Yasuhiko Sakata, Daisaku Nakatani, Shinichiro Suna, Masaya Usami, Sen Matsumoto, Toshimitsu Hamasaki, Yasuji Doi, Masami Nishino, Hiroshi Sato, Tetsuhisa Kitamura, Shinsuke Nanto, Masatsugu Hori, Issei Komuro, for the Osaka Acute Coronary Insufficiency Study (OACIS) Investigators, Low Levels of Serum n-3 Polyunsaturated Fatty Acids Are Associated With Worse Heart Failure-Free Survival in Patients After Acute Myocardial Infarction, Circulation Journal, 2013, Volume 77, Issue 1, Pages 153-162, Released December 25, 2012, [Advance publication] Released October 06, 2012, Online ISSN 1347-4820, Print ISSN 1346-9843, https://doi.org/10.1253/circj.CJ-12-0875, https://www.jstage.jst.go.jp/article/circj/77/1/77_CJ-12-0875/_article/-char/enBackground: Intake of long-chain n-3 polyunsaturated fatty acids (n-3 PUFA), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), is associated with a lower risk of atherosclerotic cardiovascular events, particularly acute myocardial infarction (AMI). However, limited data are available regarding the association between serum n-3 PUFA levels and heart failure (HF) events in survivors of AMI. Methods and Results: We evaluated whether serum DHA and EPA levels were associated with HF-free survival and HF hospitalization rates after AMI. A total of 712 patients were divided into 3 groups according to their tertile serum levels of DHA and EPA (Low, Middle, and High). Propensity-score-stratified Cox regression analysis revealed that DHA- and EPA-Low groups presented statistically significant worse HF-free survival (hazard ratio (HR) 1.68, 95% confidence interval (CI) 1.03-2.72, P=0.0358, and HR 1.69, 95% CI 1.05-2.72, P=0.0280, respectively), with the EPALow group having a higher risk of HF hospitalization (HR 2.40, 95% CI 1.21-4.75, P=0.0097) than the DHA-Low group (HR 1.72, 95% CI 0.86-3.45, P=0.1224). The relationship between a low DHA or EPA level and decreased HF-free survival was almost common to all subgroups; however, the effect of low serum EPA on HF hospitalization was prominent in male patients, and those with low levels of high-density lipoprotein cholesterol or without statin therapy. Conclusions: Low levels of circulating n-3 PUFA are associated with decreased HF-free survival in post-AMI patients
Laparoscopic anatomic resection of segment 7 of the liver using the intrahepatic Glissonean approach from the dorsal side (with video)
No full textStudies on the Chronic Gastritis Chapter III: On the Uropepsin
No full textThe author has determined the pepsin-like substance, so-called uropepsin, in the urine by the method of Bucher and Mirsky. Results obtained were as follow. The uropepsin decreased considerably in the stomach cancer, and increased in the gastric and the duodenal ulcers. In the chronic gastritis the uropepsin was moderate in amount, which was less than that in the healthy stomach. No relation has been observed between the gastric acidity and the uropepsin level; The uropepsin level was not correspond to the peptic secretory activity of the stomach. There were some cases showing high uropepsin level after gastrectomy on the duodenal ulcer. The author has concluded that the uropepsin production had been promoted by the operation which had given an influence to the adrenal gland as a kind of stress
Studies on the Chronic Gastritis Chapter I: Study on the Gastrectomy for the Chronic Gastritis
No full textForty-five cases of gastrectomies and 39 cases of exploratory laparotomies had been performed in 84 cases of the chronic gastritis. They were requested to write for their postoperative conditions and the author has made a comparative study on the results, in 37 cases of gastrectomies and in 30 cases of exploratory laparotomies, from the clinical symptomes and the resected specimens. The gastralgia as a chief complaint has been reduced from 37.8% to 16.2% by means of the gastrectomies. The results were; 1) good in 89.1% of the gastrectomized cases and in 86.6% of the exploratory cases. 2) effective in the patients had advanced atrophic gastritis. 3) excellent in the older patients, and fair in the younger. 4) no differences were encountered in between antrum gastritis and pyloric gastritis
Studies on the Metabolism of Leptospira Part Ⅱ On the respiratory metabolism of Leptospira hebdomadis
No full textIn order to investigate the enzyme activity of L. hebdomadis stock-cultured in author's department, the oxidation of some sugars, carbonic acids and amino acids by the resting organism cultured on vovine serum supplemented Korthof's media was studied. And the results were as follows. 1) It was found that L. hebdomadis was capable of aerobic metabolism as like as L. icterohaemorrhagiae. 2) In the light of sugar metabolism, the organism had the higher enzyme activity to hexose oxidation: but it had remarkably low to pentose oxidation. The oxidative activities on carbonic acids and amino acids was lower than that of true bacteria, though the activity on some substrates, i. e. aspartic acid, glutamic acid, pyruvic acid, succinic acid, and lactic acid, was fairly high. 3) The organism showed the transamination reactions between glutamic acid and aspartic acid, and also between glutamic acid and alanine. 4) Although the author caried out the experiment of additional effect of KCN, NaF, monoiodacetic acid, sodium arsenite, Mg(++) and Fe(++) in order to investigate the metabolic pathway of glucose, it could not establish the metabolic pathway so far as the results obtained
Studies on the Chronic Gastritis Chapter II: On the Gastric Juice and the Pepsin
No full textThe author has determined pepsin in the chronic gastritis by Bucher, Grossman, Ivy method and compared with it in the other stomach diseases. 1) The fasting pepsin level; 87.3 P. U.(Hb) in the gastric ulcer, 54.8 P. U.(Hb) in the stomach cancer, 102.0 P. U.(Hb) in the gastric ulcer, and 183.6 P. U.(Hb) (the highest in all) in the duodenal ulcer. Pepsin has been proved even in the case of achlorhydria in the chronic gastritis. 2) Gastric secretion by the use of its stimilants (Histamine, Insulin, Vagostigmin, Caffeine, and dried bonito extract) increased in the pepsin level in every case, and was marked especially by the vagus stimulant. Pepsin level was considerably elevated in some of the hypochlorhydria in the chronic gastritis and especially by the vagus stimulant. Acidity and pepsin level, in general, went side by side on the use of the stimulants excepting histamine, and those relation was definite in the caffeine and in the dried bonito extract. The elevation of the pepsin level was much higher than that of the acidity, in insulin and in vagostigmin
A Doppler Catheter Technique Using Fast Fourier Spectrum Analysis for the Assessment of Coronary Flow Dynamics
No full textImproved Adsorption Potential of SUGI (Cryptomeria japonica D. Don) Bark Carbonized after Steam-Treatment
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