2,367 research outputs found
Adapting Graham Greene
No full textGraham Greene was one of the most versatile writers of the 20th century, and he remains a figure of particular interest to those concerned with the relationship between literature and cinema. As well as being a skilled screenwriter in his own right, most famously with The Third Man, Greene's fiction has proved to be a perennially popular source for adaptation, appealing to the broadest range of filmmakers imaginable. In this engaging and accessibly written study, Richard J. Hand and Andrew Purssell introduce adaptation studies and its relation to Greene's works. They present new and incisive readings of key texts, including the various screen versions of Brighton Rock, The End of the Affair and The Quiet American, among others, and offer a critical examination of the industries in which Greene functioned as author, screenwriter, film critic and cultural figure. By closely exploring the various critical aspects of Greene and adaptation, and by encouraging readers to engage with the topics discussed through the inclusion of innovative exercises, Adapting Graham Greene makes a significant contribution to Graham Greene Studies and Adaptation Studies, as well as to Film and Literary Studies more generally
Functional neuroimaging demonstrates that ghrelin inhibits the central nervous system response to ingested lipid
No full textObjective: Gut-derived humoural factors activate central nervous system (CNS) mechanisms controlling energy intake and expenditure, and autonomic outflow. Ghrelin is secreted from the stomach and stimulates food intake and gastric emptying, but the relevant mechanisms are poorly understood. Nutrient-activated CNS systems can be studied in humans by physiological/pharmacological MRI (phMRI). This method has been used to examine the CNS responses to exogenous ghrelin. Design: phMRI was used to study the CNS responses in healthy people to a ghrelin bolus (0.3 nmol/kg, intravenous) in the post-prandial state, and an intravenous infusion of ghrelin (1.25 pmol/kg/min) alone and after intragastric lipid (dodecanoate, C12) in people who have fasted. Results: A ghrelin bolus decreased the blood oxygenation level dependent (BOLD) signal detected by phMRI in feeding-activated areas of the CNS in the post-prandial state. Infusion of ghrelin reversed the effect of C12 in delaying gastric emptying but had no effect on hunger. Intragastric C12 caused strong bilateral activation of a matrix of CNS areas, including the brain stem, hypothalamus and limbic areas which was attenuated by exogenous ghrelin. Ghrelin infusion alone had a small but significant stimulatory effect on CNS BOLD signals. Conclusion: Ghrelin inhibits activation of the hypothalamus and brain stem induced by ingested nutrients, suggesting a role in suppression of gut-derived satiety signals in humans.Richard B Jones, Shane McKie, Nerys Astbury, Tanya J Little, Stacey Tivey, Daniel J Lassman, John McLaughlin, Simon Luckman, Steve R Williams, Graham J Dockray, David G Thompso
Bibliography of the geology, paleontology, mineralogy, petrology, and mineral resources of Oregon
No full textby Chas. W. Henderson and J.B. Winstanley, with subject index by Graham J. Michael.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDLMaster and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDLdigitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHD
Energy barrier for 1,2-chlorine migration in α-methyl-αlpha-chlorobenzyl(chloro)carbene
No full textPT: J; CR: BONNEAU R, 1989, J AM CHEM SOC, V111, P5973 BONNEAU R, 1989, J PHYS CHEM-US, V93, P4802 GRAHAM WH, 1965, J AM CHEM SOC, V87, P4396 LIU MT, UNPUB LIU MTH, 1985, J CHEM SOC CHEM COMM, P982 LIU MTH, 1990, J AM CHEM SOC, V112, P3915 PLATZ MS, 1989, J AM CHEM SOC, V111, P6874 WARNER PM, 1984, TETRAHEDRON LETT, P4211; NR: 8; TC: 5; J9: J CHEM SOC CHEM COMMUN; PG: 3; GA: EL425Source type: Electronic(1
The DSM diagnostic criteria for Female Sexual Arousal Disorder
No full textThis article reviews and critiques the DSM-IV-TR diagnostic criteria for Female Sexual Arousal Disorder (FSAD). An overview of how the diagnostic criteria for FSAD have evolved over previous editions of the DSM is presented and research on prevalence and etiology of FSAD is briefly reviewed. Problems with the essential feature of the DSM-IV-TR diagnosis — “an inability to attain, or to maintain…an adequate lubrication-swelling response of sexual excitement” — are identified. The significant overlap between “arousal” and “desire” disorders is highlighted. Finally, specific recommendations for revision of the criteria for DSM-V are made, including use of a polythetic approach to the diagnosis and the addition of duration and severity criteria
Catalytic P-H activation by Ti and Zr catalysts
No full textCatalytic dehydrocoupling of phosphines was investigated using the anionic zirconocene trihydride salts [Cp*Zr-2(mu-H)(3)Li](3) (1a) or [Cp*Zr-2(mu-H)(3)K(thf)(4)] (1b), and the metallocycles [CpTi(NPtBu3)(CH2)(4)] (6) and [Cp*M(NPtBu3)(CH2)(4)] (M = Ti 20, Zr 21) as catalyst precursors. Dehydrocoupling of primary phosphines RPH2 (R = Ph, C6H2Me3, Cy, C10H7) gave both dehydrocoupled dimers RP(H)P(H)R or cyclic oligophosphines (RP)(n) (n = 4, 5) while reaction of tBu(3)C(6)H(2)PH(2) gave the phosphaindoline tBu(2)(Me2CCH2)C6H2PH (9). Stoichiometric reactions of these catalyst precursors with primary phosphines afforded [Cp*Zr-2((PR)(2))H][K(thf)(4)] (R = Ph 2, Cy 3, C6H2Me3 4), [Cp*Zr-2((PPh)(3))H] [K(thf)(4)] (5), [CpTi(NPtBu3)(PPh)(3)] (7) and [CpTi(NPtBu3)(mu-PHPh)](2) (8), while reaction of 6 with (C(6)H(2)tBu3)PH2 in the presence of PMe3 afforded [CpTi(NPtBu3)(PMe3)(p(C(6)H(2)tBu(3))] (10). The secondary phosphines Ph2PH and (PhHPCH2)(2)CH2 also undergo dehydrocoupling affording (Ph2P)(2) and (PhPCH2)(2)CH2. The bisphosphines (CH2PH2)(2) and C6H4(PH2)(2) are dehydrocoupled to give (PCH2CH2PH)(2) (12) and (C6H4P(PH))(2) (13) while prolonged reaction of 13 gave (C6H4P2)(8) (14). The analogous bisphosphine Me2C6H4(PH)(2) (17) was prepared and dehydrocoupling catalysis afforded (Me2C6H2P(PH))(2) (18) and subsequently [(Me2C6H2P2)(2)(mu-Me2C6H2P2)](2) (19). Stoichiometric reactions with these bisphosphines gave [Cp*Zr-2(H)(PH)(2)C6H4] [Li(thf)(4)] (22), [Cp*Ti(NPtBu3)(PH)(2)C6H4](2) (23) and [Cp*Ti(NPtBu3)(PH)(2)C6H4] (24). 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Synthesis of 3-chloro-3-methyl-d3-diazirine
No full textPT: J; CR: BURKHOLDER CD, 1980, J AM CHEM SOC, V102, P2847 GRAHAM WH, 1965, J AM CHEM SOC, V87, P4396 LIU MTH, 1974, CHEM ENG NEWS 0909, P3 ROBERTSON LC, 1972, J MOL SPECTROSC, V42, P403; NR: 4; TC: 2; J9: J ORG CHEM; PG: 1; GA: KN056Source type: Electronic(1
Reactivity and selectivity in intermolecular insertion reactions of chlorophenylcarbene
No full textPT: J; CR: DOYLE MP, 1987, CHEM DIAZIRINES, CH8 DOYLE MP, 1987, J ORG CHEM, V52, P1619 GOULD IR, 1985, TETRAHEDRON, V41, P1587 GRAHAM WH, 1965, J AM CHEM SOC, V87, P4396 KIRMSE W, 1964, CARBENE CHEM MOSS RA, 1985, REACTIVE INTERMEDIAT, V3, CH3 MOSS RA, 1986, J AM CHEM SOC, V108, P7028 PADWA A, 1969, J ORG CHEM, V34, P2728 SEYFERTH D, 1967, J ORGANOMET CHEM, V7, P405 SEYFERTH D, 1968, J AM CHEM SOC, V90, P2944 SEYFERTH D, 1970, J ORG CHEM, V35, P1989 SEYFERTH D, 1973, J AM CHEM SOC, V75, P6763 SOUNDARARAJAN N, IN PRESS J AM CHEM S STANG PJ, 1987, J AM CHEM SOC, V109, P5019 STEINBECK K, 1978, TETRAHEDRON LETT, P1103 STEINBECK K, 1981, ANGEW CHEM INT EDIT, V20, P773; NR: 16; TC: 18; J9: TETRAHEDRON LETT; PG: 4; GA: R2217Source type: Electronic(1
Southern portion of Graham Island, Queen Charlotte Islands, British Columbia.
No full textgeology, J.D. Mackenzie ; geography, British Admiralty and Department of the Naval Service of Canada, Department of Lands, British Columbia, J.D. MacKenzie ; C.O. Senecal, geographer and chief draughtsman.Scale 1:126,720. 2 miles to 1 in. (W 132 24'-W 131 55'/N 53 45'-N 53 08'). Contours shown by spot heights. Includes marginal notes and location map. Includes cross-sections and geological notes. Geology, published charts, township plans and surveys, conducted 1913-1914. To accompany Memoir by J.D. MacKenzie, Geology of Graham Island, British Columbia
Catalysis using colloidal-supported gold-based nanoparticles
No full textThe discovery of novel m aterials that can be active, selective and stable catalysts for the efficient transformation of organic molecules to useful products is of high importance. In recent years, there has been significant interest in the utilisation of supported gold-based nanoparticles that can be effective catalysts for a broad range of chemical processes. In this paper, we describe and discuss the utilisation of gold-based nanoparticles as efficient catalysts for a range of important reactions, with particular emphasis placed on our team recent research. © 2014 The Author(s)
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