5,332 research outputs found
The British ‘Bluesman’ Paul Oliver and the Nature of Transatlantic Blues Scholarship
No full textRecent revisionist studies have argued that much of what is known about music known as the blues’ has been 'invented' by the writing of enthusiasts far removed from the African American culture that created the music. Elijah Wald and Marybeth Hamilton in particular have attempted to sift through the clouds of romanticism, and tried to unveil more empirical histories that were previously obscured by the fallacious genre distinctions conjured up during the 1960s blues revival. While this revisionist scholarship has shed light on some previously ignored historical facts, writers have tended to concentrate on the romanticism of blues writing strictly from an American perspective, failing to acknowledge the genesis and influence of transatlantic scholarship, and therefore ignoring the work of the most prolific and influential blues scholar of the twentieth century, British writer Paul Oliver. By examining the core of Oliver’s research and writing during the 1950s and 1960s, this study aims to place Oliver in his rightful place at the centre of blues historiography. His scholarship allows a more detailed appreciation of the manner in which the blues was studied, through lyrics, recordings, oral histories, photography and African American literature. These historical sources were interpreted in accordance with the author’s attitudes to the commercial popular music, which allowed the ‘reconstruction’ of an African American ‘folk’ culture in which the blues became the antithesis of pop. Importantly, this study seeks to transcend dominant discourses of national cultural ownership or ethnocentrism, and demonstrate that representations of African American music and culture were constructed within a transatlantic context. The blues is music with roots in the African American experience within the United States; however, as Paul Oliver’s writing shows, its reception and representation were not limited by the same national, cultural or racial boundaries
sj-docx-1-tab-10.1177_1759720X221092374 – Supplemental material for Calcineurin inhibitors in systemic sclerosis – a systematic literature review
No full textSupplemental material, sj-docx-1-tab-10.1177_1759720X221092374 for Calcineurin inhibitors in systemic sclerosis – a systematic literature review by Nina N. Hofmann, Robert A. Ambühl, Suzana Jordan and Oliver Distler in Therapeutic Advances in Musculoskeletal Disease</p
Evidenzbasierte Therapie des Raynaud-Syndroms
Full text linkDas Raynaud-Syndrom ist mit einer Prävalenz von 3-5% ein häufiges klinisches Problem. Dennoch ist die Wirkung der meisten Therapiemöglichkeiten nur unzureichend durch kontrollierte Studien belegt. Zu den Therapien mit höherem Evidenzgrad gehört der Kalziumantagonist Nifedipin, für den in Metaanalysen sowohl bei primärem als auch bei sekundärem Raynaud-Syndrom eine verbesserte periphere Durchblutung sowie eine Abnahme der Frequenz und des Schweregrades der Raynaud-Attacken nachgewiesen werden konnte. Ähnliches gilt für intravenös appliziertes Iloprost in der Therapie des sekundären Raynaud-Syndroms bei systemischer Sklerose. Intravenös verabreichtes Iloprost verbessert darüber hinaus das Abheilen von Fingerkuppenulzera bei Patienten mit systemischer Sklerose. Vielversprechende Therapieansätze stellen Angiotensin-II-Rezeptor-1-Antagonisten (Losartan), die Kalziumantagonisten Felodipin und Amlodipin, Serotonin-Reuptake-Hemmer (Fluoxetin) und Phosphodiesterase-V-Hemmer (Sildenafil, Vardenafil) dar, die sich in kontrollierten Einzelstudien als wirksam erwiesen haben. Jedoch fehlen Erfahrungen mit größeren Patientenzahlen und längeren Anwendungszeiten, um diese Therapiemöglichkeiten abschließend zu beurteile
How Do We Identify and Manage Progressive CTD-ILD?-Update in Treatment and Guideline
No full textThe lung is a frequent target of autoimmune-mediated injury in patients with rheumatic diseases. Not infrequently, respiratory involvement may be the presenting manifestation of connective tissue diseases (CTDs). The prevalence of interstitial lung disease (ILD) in rheumatoid arthritis is about 20 to 30% of patients, while ILD may occur in 20 to 50% of patients with idiopathic inflammatory myositis, 40-50% or more of patients with systemic sclerosis, 2 to 5% of patients with systemic lupus erythematosus, 20 to 60% of patients with mixed connective tissue disease, and up to 25% of patients with Sjögren’s syndrome. Rheumatic disease-associated lung involvement is a major cause of morbidity and mortality in these patients. It shows a considerable heterogeneity in incidence and prevalence, clinical course, and the involved lung structure depending on the underlying rheumatic disease. Each rheumatic disease is associated with a characteristic pattern of their lung disease. The standard therapy has traditionally been immunosuppressant. With the evolvement of treatment, anti-fibrotic is now indicated for chronic fibrosing ILDs with a progressive phenotype, including autoimmune disease-associated ILD. By targeting the underlying mechanism of pulmonary fibrosis, it is shown that the annual rate of FVC decline can be reduced by more than 50%. In this lecture, Prof. Oliver Distler and Prof. Toby Maher will review the importance of timely treatment, the management practices and treatment guidelines for CTD-ILD
A Reading By Poet Mary Oliver
Full text linkMary Oliver\u27s poetry, with her lyrical connection to the natural world, has firmly established her in the highest realm of American poets. She is renowned for her evocative and precise imagery, which brings nature into clear focus, transforming the everyday world into a place of magic and discovery. As poet Stanley Kunitz has said, Mary Oliver\u27s poetry is fine and deep; it reads like a blessing. Her special gift is to connect us with our sources in the natural world, its beauties and terrors and mysteries and consolations. Please join Pulitzer Prize-winning poet Mary Oliver as she shares her joyous, accessible, and intimate observations of the natural world.
Mary Oliver is the celebrated author of more than a dozen books of poetry and prose. With her lyrical connection to the natural world, Oliver\u27s poetry has firmly established her in the highest realm of American poets. Oliver has been honored with the National Book Award for Poetry, the Pulitzer Prize for Poetry, and a Guggenheim Foundation Fellowship, among others
"Hi, fellas. come on in." Norman Carlson, the Federal Bureau of Prisons, and the Rise of Prison Fellowship
Full text linkThis is a pre-copyedited, author-produced version of an article accepted for publication in the Journal of Church and State following peer review. The version of record - Kendrick Oliver; “Hi, Fellas. Come on in.” Norman Carlson, the Federal Bureau of Prisons, and the Rise of Prison Fellowship, Journal of Church and State, Volume 55, Issue 4, 1 December 2013, Pages 740–757 - is available online at: https://doi.org/10.1093/jcs/css05
BA21570_Khanna_Online_supplementary_data – Supplemental material for Patient perception of disease burden in diffuse cutaneous systemic sclerosis
No full textSupplemental material, BA21570_Khanna_Online_supplementary_data for Patient perception of disease burden in diffuse cutaneous systemic sclerosis by Dinesh Khanna, Yannick Allanore, Christopher P Denton, Marco Matucci-Cerinic, Janet Pope, Barbara Hinzmann, Siobhan Davies, Janethe de Oliveira Pena and Oliver Distler in Journal of Scleroderma and Related Disorders</p
Biography of Mary Jane Oliver
No full textTypescript of a sketch biography about Mary Jane (Oliver) Barlow, who came came from England around 1851 and with her husband, Oswald Barlow, helped to settle Saint George. Author unknown, but copied on January 13, 1937 by Virginia M. Lee of the Federal Writers Project, WPA, at Ogden, Uta
Role of MicroRNAs in Fibrosis
Full text linkFibrosis is the leading cause of organ dysfunction in diseases such as systemic sclerosis, liver cirrhosis, cardiac fibrosis, progressive kidney disease, and idiopathic pulmonary fibrosis. The hallmark of fibrosis is tissue remodeling with excess deposition of extracellular matrix components, predominantly collagens. Different cell types, cytokines, growth factors, and enzymes interact in complex pathogenic networks with myofibroblasts playing a pivotal role. MicroRNAs are small non-coding RNAs acting as negative regulators of gene expression at the post-transcriptional level. MicroRNAs have been associated with many basic cellular processes as well as with a wide spectrum of diseases, most notably cancer. This review provides a comprehensive overview of microRNAs regulating profibrotic pathways and extracellular matrix synthesis. The potential of miRNA for targeted therapeutic approaches in fibrotic disorders is also discussed
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