208 research outputs found
Wo zhe yi nian
No full textby Fey Shiaw tong.Live recording.Prof. Rulan Chao Pian read "During my past year" by Fei Xiaotong.Electronic reproduction from Rulan Chao Pian Audio Cassette Collection.Read in Chinese.by Fey Shiaw tong
Identification of biochemical reaction networks: an observer based approach
No full textDynamic models present a fundamental tool in systems biology, but rely on kinetic parameters, such as association and dissociation constants. Their direct estimation from studies on isolated reactions is usually expensive, time-consuming or even infeasible for large models. As a consequence, they must be estimated from indirect measurements, usually in the form of time-series data. We describe an observer-based parameter estimation approach taking the specific structure of biochemical reaction networks into account. Considering reaction kinetics described by polynomial or rational functions, we propose a three step approach. In a first step, the estimation of not directly measured states is decoupled from the estimation of the parameters using a suitable model extension. In a second step, a specially suited nonlinear observer estimates the extended state. Based on the obtained state estimates, the parameter estimates are calculated in a straightforward way in the final step. The applicability of the approach is exemplified considering a simplified model of the circadian rhythm
Funny Feminism: Reading the Texts and Performances of Viola Spolin, Tina Fey and Amy Poehler, and Amy Schemer
No full textThis study examines the feminism of Viola Spolin, Tina Fey and Amy Poehler, and Amy
Schumer, all of whom, in some capacity, are involved in the contemporary practice and performance of feminist comedy. Using various feminist texts as tools, the author contextually and theoretically situates the women within particular feminist ideologies, reading their texts, representations, and performances as nuanced feminist assertions. Building upon her own experiences and sensations of being a fan, the author theorizes these comedic practitioners in relation to their audiences, their fans, influencing the ways in which young feminist relate to themselves, each other, their mentors, and their role models. Their articulations, in other words, affect the ways feminism is contemporarily conceived, and sometimes, humorously and contentiously advocated
A Tale of the Terminally Fey: A Modern Take on Collaborative Folklore
No full textWriting has long been seen as a solitary affair, but this was not always the case. Before widespread literacy, stories were told and retold through the power of speech. Whole communities came together to weave tales and myths. Recently that tradition has been making a return to mainstream media with the renaissance of tabletop role-playing games, which serve as a standard vehicle for group collaboration. A Tale of the Terminally Fey is an attempt to reconcile the collaborative, off-the-cuff nature of oral storytelling with traditional narratives. The author has adapted the transcripts of live sessions into the first chapter of a novel that would follow the characters through one of these storytelling campaigns
Tina Fey: "Quality" Comedy and the Body of the Female Comedy Author
No full textThis book chapter examines the television authorship of comedy producer-performer Tina Fey. It takes Fey’s comedy as case study for the examination of the ways in which American “quality” TV comedy of the early 21 st century accommodates thematisations of gender politics and popular feminist discourses. Fey’s work is particularly relevant for this investigation, since her celebrity and comedy mobilise popular discourses around female authorship, liberal feminism, performance, and body politics in the context of American prestige comedy. In the chapter I unpack media controversies around her star text and comedy – particularly as presented in her series "30 Rock" (2006-2013) – which originated in her mobilisation of a “feminist” comic persona and in this persona’s reflection on the gendered dualism of comedy performance and authorship. As I argue, a discursive dichotomy of “writer” versus “performer” of female-centred comedy, much influenced by
the postfeminist cultural paradigm, shapes and dominates Fey’s public image, helping to negotiate her presence in the higher echelons of American comedy
Parameter identification for biological models
No full textThis thesis concerns the identification of dynamic models in systems biology. and is structured into two parts. Both parts concern building dynamic models from observed data, but are quite different in perspective, rationale and mathematics. The first part considers the development of novel identification techniques that are particularly tailored to (molecular) biology and considers two approaches. The first approach reformulates the parameter estimation problem as a feasibility problem. This reformulation allows the invalidation of models by analysing entire parameter regions. The second approach utilises nonlinear observers and a transformation of the model equations into parameter free coordinates. The parameter free coordinates allow the design of a globally convergent observer, which in turn estimates the parameter values, and further, allows to identify modelling errors or unknown inputs/influences. Both approaches are bottom up approaches that require a mechanistic understanding of the underlying processes (in terms of a biochemical reaction network) leading to complex nonlinear models. The second part is an example of what can be done with classical, well developed tools from systems identification when applied to hitherto unattended problems.In particular, part two of my thesis develops a modelling framework for rat movements in an experimental setup that it widely used to study learning and memory.The approach is a top down approach that is data driven resulting in simple linear models
Parameter identification for biological models / Identification de param\ue8tres de mod\ue8les biologiques
No full textExperimental Determination of CCT Diagrams and Simulated HAZ Microstructures in Low-Alloy Pipeline Steel for H2 Transportation
No full textThis study investigates the suitability of low-alloy pipeline steels for hydrogen transportation, focusing on the development of weld microstructures. Previous research has been limited by a deficiency in the understanding of how different microstructural components respond to trapped hydrogen. By developing Continuous Cooling Transformation (CCT) diagrams through dilatometry analysis, this study explores the impact of t8/5-cooling times (the time between 800 °C and 500 °C) on the microstructure and mechanical properties of the HAZ compared to the base material. The findings provide valuable insights into how cooling times influence transformation temperatures and microstructure development, which, in turn, affect hydrogen diffusion and absorption. These findings establish a foundation for future investigations into hydrogen's impact on weld microstructures, including experimental studies, with the aim of optimizing welding practices and enhancing resistance to hydrogen-assisted cracking. Ultimately, this research contributes to improving the safety and reliability of hydrogen transportation systems in commonly used industrial pipeline steels
Thermophysically Simulated Weld HAZ and CCT Diagram of� High Strength Low Alloy Pipeline Steel
No full textKurzvorstellung der laufenden Projekte "Wasserstoffabhängige mechanische Eigenschaften der Schweißnahtgefüge niedriglegierter Stähle für Ferngasleitungen" und "Praktikable Prüfung geschweißter Ferngasleitungen aus niedrig-legierten Stählen für den sicheren Transport von Wasserstoff" mit kurzem Ergebnisstand und zukünftiger Versuchsplanung/Outloo
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