244 research outputs found
Application of lipid biomarkers in deciphering quaternary human evolution in the Indian subcontinent: An integrative review
No full textThis comprehensive review article presents an integrated application of lipid biomarkers to unravel the intricate narrative of Quaternary human evolution in the Indian subcontinent. The study highlights the empirical and experimental foundations laid by numerous investigations, contributing to our current knowledge of sedimentary deposits, ecofacts, and artifacts that preserve organic residues containing lipid biomarkers. The advancements in lipid analysis, with a specific emphasis on enhanced analytical tools and approaches to data acquisition and interpretation, have provided an intuitive paradigm for comprehending various archaeological investigations. Concise documentation is provided on the process of establishing protocols for extracting and isolating lipid biomarkers, as well as the instrumental developments that enable the detection, identification, and quantification of these biomarkers. The utilization of compound groups such as fatty acids, alcohols and triacylglycerides (TAGs) for dietary reconstruction and subsistence transition studies is explored. Molecular markers including n-alkanes, lignins, terpenoids, and the related parametric ratios have also been discussed, offering an elaborate understanding of vegetation shift, thereby suggesting environmental and climatic change. An overview of relevant studies conducted within the Indian subcontinent and worldwide underscores the application of suggested lipid markers and subsequent technological advancements in archaeological contexts. The work highlights the paucity of studies within the Indian subcontinent, underlining the imperative for more extensive research to provide profound insights and address lingering questions surrounding human history
FDI Spillovers, Innovation and the Role of Industrial Clusters: Evidence from Innovative Indian Manufacturing Firms
No full text© 2025, Elsevier B.V. The attached document (embargoed until 08/09/2026) is an author produced version of a paper published in Economic Modelling uploaded in accordance with the publisher’s self-archiving policy. The final published version (version of record) is available online at the link. Some minor differences between this version and the final published version may remain. We suggest you refer to the final published version should you wish to cite from it
Closed Form HJB Solution for Path Planning of a Robot Manipulator with Warehousing Applications
No full textReal-time optimal path planning for robotic manipulations in task space is a very fundamental and important problem. In this paper, the problem of generating robot trajectories in an obstacle-ridden environment is formulated under an optimal control framework using Hamilton-Jacobi-Bellman (HJB) equation. The novel contribution of this paper is that a closed form HJB control solution (a necessary and sufficient condition for global optimality of a control solution with respect to a cost function) has been achieved for generating real-time optimal trajectories for a robot manipulator. In contrast with the decoupled end-effector path planning and subsequent trajectory generation, the proposed scheme can exploit sensory input for real-time trajectory generation where the end-effector path as well as the joint trajectory is recomputed online while satisfying the real-time constraints. The stability and the performance of the proposed control framework is shown theoretically via Lyapunov approach and also verified experimentally using a 6 degrees of freedom (DOF) Universal Robot (UR) 10 robot manipulator. It is shown that a significant saving in cost metrics can be obtained over similar trajectory generation approaches from the state-of-the-art with obstacle-ridden environment and also has better performance in high speed tracking applications. Warehouse applications of the proposed scheme in case of static and dynamic targets with respect to the robot manipulator is also included.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Learning & Autonomous Contro
A High Gain Elliptical Slot Antenna for Lower C-band and X-band Application
No full textA novel design of printed CPW-fed planar elliptical slot antenna with transformed circular patch is presented here for dual-band application. The obtained impedance band finds application in lower C-band satellite communication and entire X-band with significant gain. Electromagnetic wave simulator HFSS® is used to simulate the structure and the study of parameter behaviour is carried out. The performance of the proposed antenna in terms of return loss, radiation pattern and gain are analysed. Furthermore, the same structure is designed and simulated with microstrip feed line. An imperial formula in terms of axial length and ellipticity ratio of the elliptical slot is formulated to find the lower edge frequency of impedance bandwidth
ROLE OF RETICULOCYTE HEMOGLOBIN CONTENT IN DIAGNOSIS OF IRON DEFICIENCY ANEMIA
No full textObjectives: Anemia is a global problem of immense health significance affecting persons of all ages and economic groups. Iron deficiency anemia (IDA) is the most common type of anemia met with in clinical practice. For IDA diagnosis, estimation and treatment, many indices such as serum iron (SI), total iron binding capacity (TIBC), serum ferritin (SF), and soluble transferrin receptor assay are used. But reticulocyte hemoglobin content (CHr) is called as the gold standard for diagnosing IDA as it is the most valuable screening tool for identifying IDA with a sensitivity of 94% and specificity 80% and differentiates IDA from anemia of systemic disease. The present study was undertaken to evaluate CHr as a most efficient marker in diagnosing IDA.
Methods: This prospective observational study was carried out in the Department of General Medicine of M.K.C.G. Medical College and hospital, Berhampur, Odisha, India, from October 2017 to October 2019. Sixty microcytic hypochromic patients of either sex >18 years of age admitted in the medicine ward fulfilling the inclusion and exclusion criteria were included in this study. After taking detailed history and clinical examination, laboratory investigations including complete blood count, SI, serum, ferritin, serum transferrin saturation, TIBC, CHr, and bone marrow aspiration with iron stain were done in all patients.
Results: In the study group of 60 patients, 10 (16.66%) patients had mild anemia, 17 (28.33%) had moderate anemia, and 33 (55%) had severe anemia. Mean hemoglobin of the patients was 6.86 g/dL and SD was 1.95 g/dL. Nineteen (31.66% patients) had TIBC in the range of 351–400 μg/dl. Mean±SD of serum TIBC was 333.91±67.26 μg/dL. Thirty-nine patients (65%) had transferrin saturation in the range of 0.1–10%. The mean±SD of the study group was 13.68±3.22%. Fifty (83.33%) patients had SF in the range of 0–100 μg/dL. Twenty-three patients (38.33%) had CHr concentration between 15.1 and 20 pg followed by 19 (31.66%) between 20.1 and 25 pg and 18 (30%) between 25.1 and 30 pg. The mean±SD of this study was 22.14 pg±3.92.
Conclusion: CHr is found to be a potential biomarker that can be used to differentiate IDA from other causes of anemia
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