36 research outputs found

    Innovative and Effective Methodology for Determining PE Learning Outcomes in Bulgarian School

    No full text
    The problem of physical education and sports, as an integral part of the learning process in the Bulgarian school, which has a significant impact on the overall formation of the student's personality, is extremely relevant and significant, especially in terms of its effective organization and reporting. As a purposeful and organized process, physical education and sports are normatively conditioned, that is it is planned, organized and reported according to established state rules and norms – such as mandatory and standardized tests of the Ministry of Education and Science (MES), for example, which in their entirety place emphasis on the physical capacity of students. This circumstance reflects on the goals and objectives set in the curricula for the subject of physical education in the Bulgarian school, which do not affect the age and individual characteristics of students and do not refer to clear and precise criteria for reporting the results.All this creates conditions for directing the efforts of physical education teachers to the implementation of activities that do not fully form the physical culture of students, on the one hand, and on the other, create conditions for its biased and incorrect reporting and evaluation.The purpose of this article is to prove the relevance of the problem of the need for more effective reporting of the results of physical education and sports in the Bulgarian school through the application of innovative methods included in a developed and tested author's theoretical model

    L'effet des statines sur l'activation des cellules endothéliales par les anticorps antiphospholipides

    No full text
    Le syndrome des anti-phospholipides est caractérisé par les taux élevés des anticorps anti-phospholipides (APLA) associé à une thrombophilie ou des pertes fœtales répétées. Plusieurs études ont montré que les APLA sont capables d'activer les cellules endothéliales in vitro. Les statines, non-seulement diminuent les taux de cholestérol, mais ont aussi été décrites comme ayant des propriétés anti-inflammatoires. Nous avons étudié, par analyse de cytométrie en flux, l'effet des statines sur l'expression des molécules d'adhésion leukocytaires par les cellules endothéliales stimulées pas les APLA ou le TNF et déterminé le mécanisme de cet effet. Nous avons observé que les statines augmentent l'effet des APLA ou du TNF sur l'expression des molécules d'adhésion. L'effet des statines à été bloqué par une co-incubation avec le mévalonate ou le geranylgeranyl pyrophosphate et mimé par GGTI-286, un inhibiteur de geranylgeranyl transférase. Nos résultats montrent que l'effet des APLA sur les cellules endothéliales in vitro est augmenté par les statines. L'effet des statines est dû à des modifications de protéines geranylgeranylées

    Preventive Activities the Teacher to Prevent Adolescent Aggression

    No full text
    The problem of aggressiveness of adolescents is one of the central socio-pedagogical problems that affects society at large, causes deep concern among teachers, parents, and causes an acute scientific and practical interest of foreign and native researchers. In connection with the spread of aggression in the adolescent environment, there is a need to consider its prevention and correction in school. Diagnostic research and prevention of adolescent aggression at school is an integral component of the activity of classroom teacher. The article deals with the essence of aggressiveness, especially aggressive behavior of teenagers at school, discusses the factors that influence the expression of aggression, specifically the destruction of the traditional models of education. It also points to the need to apply effective methods and techniques for preventing and correcting the aggressive behavior of adolescents in school by means of classroom teacher's activities. The material may be useful for classroom teachers, specialists of psychological services accompanying educational institutions

    Las prohibiciones de registro de la marca en la Unión Europea

    Get PDF
    Este trabajo de investigación se ha centrado en llevar a cabo un análisis de las prohibiciones de registro de la marca de la Unión Europea, las cuales coinciden tanto a nivel nacional como europeo. Para la investigación hemos analizado varias sentencias donde se puede ver como muchas multinacionales incurren en estas prohibiciones a la hora de llevar a cabo el registro, motivo por el cual se les deniega el registro de la marca. Además del estudio de las clases de prohibiciones de registro de la marca en la Unión Europea, hemos analizado otros aspectos de gran interés como el derecho de marca como derecho exclusivo de utilización, funciones y características o clases de marcas. Todo ello apoyándonos en opiniones de autores expertos en la materia
    corecore