107 research outputs found
sj-docx-1-jad-10.1177_10870547221085503 – Supplemental material for ADHD in Adults: A Systematic Review and Meta-Analysis of Prevalence Studies in Outpatient Psychiatric Clinics
No full textSupplemental material, sj-docx-1-jad-10.1177_10870547221085503 for ADHD in Adults: A Systematic Review and Meta-Analysis of Prevalence Studies in Outpatient Psychiatric Clinics by Dimitrios Adamis, Caroline Flynn, Margo Wrigley, Blánaid Gavin and Fiona McNicholas in Journal of Attention Disorders</p
Studies on epidemiology and co-morbidities of adult Attention Deficit Hyperactive disorder in (ADHD) in northwest area of Ireland
No full textThis thesis is an endeavour to examine epidemiology of Adult ADHD in people attending mental health services in northwest area of Ireland. In addition, it examined mental health comorbidities including personality disorders, functionality, and quality of life in adults newly diagnosed with ADHD in their adult life. Further the association of childhood symptoms as they measured with the retrospective scale Wender Utah Rating Scale (WURS) with specific mental health disorders in adulthood (including ADHD) was explored. Finally, a new scale was developed and psychometrically tested which allows for the clinician routinely to measure clinical outcomes from interventions at individual level as well as overall outcomes of the service. The major findings of those studies where that there is a considerable number of undiagnosed or misdiagnosed ADHD cases among people attending adult mental health services (prevalence 16.1%). A meta-analysis of four similar studies shows a pooled prevalence of 16.31%. Also, the number of comorbid mental disorders in people with ADHD was higher compared to those without ADHD, and those with ADHD had significantly higher rates of depression and recurrent depression compared to those without. In the same line regarding personality disorders (PDs) the majority of those with ADHD had at least one comorbid PD the most common being the Dependent PD, followed by Depressive PD. Additionally, in terms of functionality and quality of life, those diagnosed with ADHD had significantly poorer functionality and lower quality of life compared to those with similar symptomatology but without ADHD diagnosis. Moreover, it was found that there was an association between certain childhood behaviours classified by WURS and later diagnosis in adulthood with ADHD, personality disorders, and substance abuse. Finaly, the new ADHD Clinical Outcome Scale (ACOS) tested in a sample of 148 participants, and it was found with high internal consistency (83%), high Inter-rater reliability (87%), good concurrent validity with Weiss Functional Impairment Rating Scale, 48%, and Adult ADHD Quality of Life Questionnaire (57%) and it was sensitive to clinical changes.
The above results of the studies which included in this thesis, had a major impact on the design and development of a new adult ADHD service in national level, and influenced the guidelines proposed in the Model of Care from the National Clinical Programme for Adult ADHD. In addition, at the local level the place where this research was carried out was the first where an ADHD tertiary clinic developed under the auspices of the National Clinical Programme
Insulin-Like Growth Factor I and the Pathogenesis of Delirium: A Review of Current Evidence
No full textDelirium is a frequent complication in medically ill elderly patients that is associated with serious adverse outcomes including increased mortality. Delirium risk is linked to older age, dementia, and illness that involves activation of inflammatory responses. IGF-I is increasingly postulated as a key link between environmental influences on body metabolism with a range of neuronal activities and has been described as the master regulator of the connection between brain and bodily well-being. The relationships between IGF-I and ageing, cognitive impairment and inflammatory illness further support a possible role in delirium pathogenesis. Five studies of IGF-I in delirium were identified by a systematic review. These conflicting findings, with three of the five studies indicating an association between IGF-1 and delirium occurrence, may relate to the considerable methodological differences in these studies. The relevance of IGF-I and related factors to delirium pathogenesis can be clarified by future studies which account for these issues and other confounding factors. Such work can inform therapeutic trials of IGF-I and/or growth hormone administration
Previous studies reported that anger and hostility are often presented in the victims of a disaster. This study investigates the symptoms of anger and hostility after a wildfire disaster in a rural area of Greece. Cross sectional case control study of adult population (18-65 years old). Face to face interview. Data collected were demographic, Symptom Checklist 90-Revised for assessment of hostility, type and number of losses, trust in institutions personal and social attitudes. It was found that more of the victims of the wildfires reported symptoms of hostility compared to controls but this difference was disappeared when we adjust for other variables. Risk factors for development of hostility among the victims were mistrust in military forces and media, high levels of anxiety and distress, younger age and having higher education. It was concluded that anger and hostility after a disaster perhaps are not only related to disaster but other factors concerning demographic and personal characteristics may play an important role
Δυναμική προσαρμογή εικονικού ή επαυξημένου περιβάλλοντος βάσει βιοανάδρασης προερχόμενης από αισθητήρες
No full textThe Role of Insulin-Like Growth Factor 1 in Delirium: A Systematic Review and Meta-Analysis
No full textBackground: The relationship between delirium and low levels of insulin-like growth factor 1 (IGF-1) is contradictory and uncertain. We hypothesised that low levels of IGF-1 are a predisposing factor for delirium in medical and abdominal surgical cohorts, in contrast to other surgical cohorts. Aims: Systematic review and meta-analysis investigating the association between peripheral levels of IGF-1 and delirium in medical and surgical patients to explore if there are distinct patterns of associations by using subgroup meta-analysis. Methods: PubMed, Scopus, CINAHL, Cochrane, and Embase databases were searched. Inclusion criteria were prospective studies in medical and surgical populations and available data. The following were collected: the setting (surgical/medical), the type (orthopaedic surgery, abdominal, cardiovascular, or medical), the number of participants, mean age, the number of delirious patients, scale/criteria for delirium, IGF-1 levels, and MMSE. Results: Thirteen studies were included and analysed. Low levels of IGF-1 are significantly associated with delirium in abdominal surgical samples and medical samples but not in the other surgical samples. Age, cognition, and the setting (medical vs. surgical) do not have any significant effect on the differences in IGF-1 levels between those with and without delirium. Discussion: Delirium in acute medical and abdominal surgery is triggered by low IGF-1 which may reflect chronic conditions like frailty/cachexia/sarcopenia, while in other surgeries perhaps from an inflammatory process. Conclusions: Low peripheral levels of IGF-1 are a predisposing factor for delirium only in acute medical and abdominal surgery. More studies are needed to confirm and to explore further this finding
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MISAME
No full text"Metallika Glypta III", is the third release of a series of three works under the same title, was written in February 1972. Their processing and the final realization were made in the studio of the author.
The sculpture exhibition of Loukoupoulos (1972) was the starting point of "Metallika Glypta". The idea of using sounds taken exclusively from metal sculptures was a particularly challenging stimulus. The musical activity starts at the first moment when the sound material was collected. The ideas on the making of sounds were preconceived, they came one after the other.
Each successful essay highlights the emotion of the first creative success. The same emotion was found in later treatments and their inclusion in large units. The form of the work -fluent and evolving without stop- serves the integration of musical ideas in a composition that has not denied the original material. The feeling of metal is thus always present
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