1,235 research outputs found
Risk factors and outcomes after interruption of sedation in subarachnoid hemorrhage (ROUTINE-SAH)—a retrospective cohort study
No full textIntroductionAneurysmal subarachnoid hemorrhage (aSAH) often necessitates prolonged sedation to manage elevated intracranial pressure (ICP) and to prevent secondary brain injury. Optimal timing and biomarkers for predicting adverse events (AEs) during interruption of sedation (IS) after prolonged sedation are not well established. To guide sedation management in aSAH, we aimed to explore the frequency, risk factors, and outcomes of IS in aSAH.MethodsIn a retrospective cohort study, a total of 148 patients with aSAH from January 2015 to April 2020 were screened. In total, 30 patients accounting for 42 IS were included in the analysis. Adverse events (AEs) during IS were used as core outcome measures and were categorized into neurological and non-neurological AEs. Baseline characteristics, clinical parameters before IS, AEs, and functional outcomes were collected using health records. Statistical analysis used generalized linear mixed-effects models with regularization to identify candidate predictors with subsequent bootstrapping to test model stability. As an exploratory analysis, multivariate linear and logistic regression was used to analyze the association between IS and intensive care unit length of stay, duration of mechanical ventilation, and functional outcomes.ResultsThe mean age was 56.9 (SD 14.8) years, and a majority of the patients presented with poor-grade SAH (16/30, 53.3%). Neurological and non-neurological AEs occurred in 60.0% (18/30) of the patients. Timing, number of IS attempts, ICP burden, craniectomy status, level of consciousness, heart rate, cerebral perfusion pressure, oxygen saturation, fraction of inspired oxygen, and temperature were selected as candidate predictors. Through bootstrapping, elapsed time since disease onset (OR 0.85, 95% confidence interval (95% CI) 0.75–0.97), ICP burden (OR 1.24, 95% CI 1.02–1.52), craniectomy (OR 0.68, 95% CI 0.48–0.69), and oxygen saturation (OR, 0.80 0.72–0.89) were revealed as relevant biomarkers for neurological AEs, while none of the pre-selected predictors was robustly associated with non-neurological AEs.ConclusionIn aSAH, complications during the definite withdrawal of sedation are frequent but can potentially be predicted using clinical parameters available at the bedside. Prospective multicenter studies are essential to validate these results and further investigate the impact of IS complications
[Secondary prophylaxis of ischemic stroke]
No full textThe secondary prophylaxis of ischemic stroke provides an enormous therapeutic potential due to the high frequency of recurrent thrombembolic events and the exceptional importance of modifiable cardiovascular risk factors for the individual risk of stroke. In this respect, anti-thrombotic, interventional and surgical treatment options must be selected based on the respective etiology. Furthermore, meticulous optimization of risk factors is essential for effective long-term care. Close interdisciplinary and intersectoral collaboration is crucial, especially in the long-term treatment
sj-pdf-1-eso-10.1177_23969873231209616 – Supplemental material for Cost-effectiveness of endovascular treatment versus best medical management in basilar artery occlusion stroke: A U.S. healthcare perspective
No full textSupplemental material, sj-pdf-1-eso-10.1177_23969873231209616 for Cost-effectiveness of endovascular treatment versus best medical management in basilar artery occlusion stroke: A U.S. healthcare perspective by Dirk Mehrens, Matthias P Fabritius, Paul Reidler, Thomas Liebig, Saif Afat, Johanna M Ospel, Matthias F Fröhlich, Julian Schwarting, Jens Ricke, Konstantinos Dimitriadis, Mayank Goyal and Wolfgang G Kunz in European Stroke Journal</p
The Pixels and Sounds of Emotion: Dataset
No full textThis dataset was used in:
Makantasis, Konstantinos, Antonios Liapis, and Georgios N. Yannakakis. "The Pixels and Sounds of Emotion: General-Purpose Representations of Arousal in Games." IEEE Transactions on Affective Computing (2021).
If you use this dataset please cite the following papers:
@inproceedings{camilleri2017towards,
title={Towards general models of player affect},
author={Camilleri, Elizabeth and Yannakakis, Georgios N and Liapis, Antonios},
booktitle={2017 Seventh International Conference on Affective Computing and Intelligent Interaction (ACII)},
pages={333--339},
year={2017},
organization={IEEE}
}
@article{makantasis2021pixels,
title={The Pixels and Sounds of Emotion: General-Purpose Representations of Arousal in Games},
author={Makantasis, Konstantinos and Liapis, Antonios and Yannakakis, Georgios N},
journal={IEEE Transactions on Affective Computing},
year={2021},
publisher={IEEE}
}Part of this dataset was created and processed in the framework of the TAMED project (Grant Agreement 101003397) funded by the European Union's H2020 research and innovation programme
Acquiescent Spreaders: Occidentalism and Peripatetic Memory in Athens, Greece. COVID-19: Concepts of Sickness and Wellness
No full textIn this chapter, anthropologist and visual culture specialist Konstantinos Kalantzis explores Greek responses to the COVID19 pandemic and its global media coverage. He is particularly interested in questions of power and imagination as well as the problem of representing and visualizing “crisis”, with photographic meditations from a walk by the author/photographer
Alan Nadel, The Theatre of August Wilson
No full textAlan Nadel, The Theatre of August Wilson London: Methuen Drama, 2018. Pp. 224. ISBN: 9781472530486. Konstantinos Blatanis Published as part of Methuen Drama’s series of critical companions, this latest addition to the ever-growing scholarship on August Wilson’s work bears the signature of an author whose expertise on the playwright is significant in terms of both time and depth. Over the span of the past three decades, Alan Nadel has offered to this field a number of original and influenti..
The re-vocalization of logos?:thinking, doing and disseminating voice
No full textThis is the author accepted manuscript. The final version is available from the publisher via the link in this recor
Improving the speed and accuracy of indoor localization:
No full textAdvances in technology have enabled a large number of computing devices to communicate wirelessly. In addition, radio waves, which are the primary means of transmitting data in wireless communication, can be used to localize devices in the 2D and 3D space. As a result there has been an increasing number of applications that rely on the availability of device location. Many systems have been developed to provide location estimates indoors, where Global Positioning System (GPS) devices do not work. However, localization indoors faces many challenges. First, a localization system should use as little extra hardware as possible, should work on any wireless device with very little or no modification, and localization latency should be small. Also, wireless signals indoors suffer from environmental effects like reflection, diffraction and scattering, making signal characterization with respect to location difficult.
Moreover, many algorithms require detailed profiling of the environment, making the systems hard to deploy.
This thesis addresses some of the aforementioned issues for localization systems that rely on radio properties like Received Signal Strength (RSS).
The advantage of these systems is that they reuse the existing communication infrastructure, rather than necessitating the deployment of specialized hardware. Specifically, we improved the latency of a particular localization method that relies on Bayesian Networks (BNs). This method has the advantage of requiring a small size of training data, can localize many devices simultaneously, and some versions of BNs can localize without requiring the knowledge of the locations where signal strength properties are collected.
We proposed Markov Chain Monte Carlo (MCMC) algorithms and evaluated their performance by introducing a metric which we call relative accuracy.
We reduced latency by identifying MCMC methods that improve the relative accuracy to solutions returned by existing statistical packages in as little time as possible. In addition, we parallelized the MCMC process to improve latency when localizing devices whose number is on the order of hundreds. Finally, since wireless transmission is heavily affected by the physical environment indoors, we investigated the impact of using multiple antennas on the performance of various localization algorithms. We showed that deploying low-cost antennas at fixed locations can improve the accuracy and stability of localization algorithms indoors.Ph.D.Includes bibliographical references (p. 103-106)by Konstantinos Kleisouri
Aghios Konstantinos church in Athens. Conservation planning
No full textThis piece shows the conservation project made for Aghios Konstantinos church, Athens, Greece. Starting from the investigation of the urban development of the city, passing through the study of the architectural grammar of the building and eventually addressing to the material characterisation and pathologies of the church, this work tries to provide a strong analytical support for the conservation intervention. We investigated Athens urban development dividing the timeline in eight phases, from the Ancient Age until now. Aim of this task is to supply a strong understanding of why Aghios Konstantinos church was built in a particular point of the city, and which are its historic and artistic values that need to be preserved and passed on future generations. We narrowed the focus of our investigation lens afterwards. We studied the building concentrating on its architectural grammar. Precisely, the architectural style is both complex and traditional: Kaftantzoglou, the author, tried to merge byzantine elements with classical ones, in a modern eclectic-neo-classical shape. We examined material characterisation and investigation of damage using NORMAL tables, separating different materials and individuating typical pathologies for each of them in the main façade. Atmospheric agents and, mainly, humidity caused most decays. Interventions on the façade were planned strictly respecting minimum interventum, sustainability and reversibility. Finally, a survey of structural damage indoors and outdoors revealed stability problems in the vault, in the arches, and in the pillars below. Although the church was built only in the 19th century, it showed serious structural damages, mainly caused by two strong earthquakes that occurred in 1981 and in 1999. The consolidation project focused on the dome: we planned a Fiber Reinforced Polymer (FRP) hooping around it, calculating the strains on meridians and parallels and, eventually, applying a traction verification
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