676 research outputs found

    Acute onset of hypertensive encephalopathy in a dog with right adrenal pheochromocytoma and neoplastic invasion of the caudal vena cava: Case report and review of the literature

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    Background: Canine pheochromocytomas (PCCs) are rare tumors of the adrenal medulla. Clinical signs are often vague, resulting in intermittent catecholamine over secretion or neoplastic invasion of adjacent structures. Case Description: A 12-year-old Epagneul Breton dog with a 1-year history of chronic kidney disease, was examined for acute onset of severe neurological signs. Based on clinical and instrumental data, hypertensive encephalopathy was suspected. Cardiac and abdominal ultrasound were performed. Severe hypertensive cardiopathy and a right adrenal gland mass with invasion of the caudal vena cava were diagnosed. Computed tomography imaging confirmed the suspect of invasive malignant neoplasia. Emergency pharmacological therapy was started to reduce systemic pressure, improve clinical signs, and stabilize the dog in view of surgical resolution. After initial improvement, patient conditions abruptly worsened, and euthanasia was elected. Histology examination confirmed a right adrenal PCC, with caval invasion. Conclusion: To the authors' conclusions, acute hypertensive encephalopathy is a peculiar manifestation of PCCs. Ultrasound is a useful, and rapid test to suspect PCC as it can detect adrenal alterations, caval invasion, metastasis, and cardiac sequelae consistent with the condition. PCC can mimic multiple affections, and be misinterpreted, especially when a concurrent disease has already been diagnosed. Veterinarians need to be aware that comorbidities could mask clinical signs and delay diagnosis. Furthermore, this clinical case reminds us to include PCC also in the differential diagnosis of dogs with an acute onset of severe neurological signs

    Serum digoxin concentrations in dogs with atrial fibrillation under long term digoxin treatment

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    BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia in dogs, most frequently diagnosed as chronic AF associated with a structural heart disease. The therapeutic strategy, in these cases, is based on the heart rate control and digoxin is one of the most used drugs. AIM: The aim of this work was to study the serum digoxin concentration changes in dogs with AF under long-term treatment with digoxin. Furthermore, the remission of clinical signs and the correlation between digoxinemia and other clinical and laboratory variables were retrospectively evaluated. METHODS: The prospective study was conducted on seven large breed dogs from the time of reaching the definitive digoxin dosage. Digoxinemia was determined at month: 1, 3, 6, 9, 12, then twice a year. A post hoc statistical analysis investigated the influence of selected clinical and laboratory variables on the risk to develop spikes in digoxinemia. Clinical data, heart rate, digoxin dosage (mg/m(2)), and digoxinemia (ng/ml) at all available follow-ups were retrospectively evaluated from the medical records of 17 further dogs and a linear regression analysis was performed on the whole data set. The relation between the time of remission of AF clinical signs and variables was also investigated. RESULTS: An unexpected increase in digoxin serum concentration was recorded in three dogs after one year monitoring, in absence of digoxin dosage changes. No statistical significance of all the studied variables on the risk to develop spikes of digoxinemia was registered. Two dogs, reaching digoxinemia 4.46 and 5.24 ng/ml, showed symptoms that reversed after digoxin withdrawal. From retrospective data, 88% of dogs reached complete reverse of AF clinical signs in 2.1 months from digoxin treatment starting, regardless of digoxin initial dosage, digoxinemia, and heart rate. CONCLUSION: Digoxin in monotherapy remain a good option to treat AF in dogs, anyway digoxin toxicity could emerge during long-term therapy, similarly to what happen in human medicine. Life-threatening spikes of digoxinemia could occur, especially after 1-year treatment with digoxin. It is very important that practitioners be aware of this possibility and encourage the owners to monitor digoxinemia during long-term treatment to avoid dangerous and toxic effects

    Location-Based Discovery and Network Handover Management for Heterogeneous IEEE 802.11ah IoT Applications

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    This research was funded by the Flemish IDEAL-IoT project (FWO SBO, grant nr. S004017N). The author Serena Santi is funded by the Flemish FWO SB grant (nr. 1S82120N). The author Filip Lemic was supported by the EU MSCA grant (nr. 893760). The computational resources were provided by the VSC (Flemish Supercomputer Center), funded by FWO and the Flemish Government -department EWI

    Serena Hung: a published author at 18

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    Profile of Serena Hun

    CLINICAL INSIGHTS TO ADDRESS CANINE STRONGYLOIDOSIS IN DAILY PRACTICE

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    Canine strongyloidosis by Strongyloides stercoralis is a parasitic disease emerging in Europe, which represents both a veterinary clinical issue and a public health challenge because of the zoonotic potential. The disease, not yet frequent in Europe, could induce severe clinical signs in dogs; thus, an early diagnosis and appropriate treatment are desirable. The aim of the present work is to retrospectively investigate the clinical and paraclinical findings in sick dogs naturally infected by S. stercoralis, with particular attention to ultrasound (US) changes at the gastrointestinal level. Twelve dogs were included in the study. The diagnosis was made by means of larval morphological identification on faecal samples and PCR. Most dogs presented with gastrointestinal signs; diarrhea and weight loss were the most common presenting complaint. Only one dog showed respiratory signs, associated to a parasitic cutaneous nodule. Hypoproteinaemia, anaemia, leucocytosis and an increase in alpha2-globulin fraction at serum protein electrophoresis were common (>50%) but not constant findings. The most reported US picture was a fluid-filled, distended, atonic small intestine mostly associated with altered wall layering, while the wall thickness commonly associated with chronic enteritis was only rarely reported. These changes, associated with other clinical and paraclinical alterations, could increase the suspicion of canine strongyloidosis and may direct clinicians to include strongyloidosis in the differential diagnosis of dogs with diarrhea. The histological examination at the intestinal level, available in five dogs, revealed the presence of parasites from the full-thickness biopsy, but not from the endoscopic biopsy. The critical points of diagnosis in clinical practice are also discussed

    Erratum: Lack of immunity against rubella among Italian young adults. [BMC Infect Dis., 17, (2017) (199)] Doi: 10.1186/s12879-017-2295-y

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    After publication of this article [1], the authors noted that the given names and family names of all authors had been inverted, and are therefore incorrect in the original article. In the original article, the author names appear as the following: Gallone Maria Serena, Gallone Maria Filomena, Larocca Angela Maria Vittoria, Germinario Cinzia and Tafuri Silvio. However, this is incorrect, and the author names should appear as per the below: Maria Serena Gallone, Maria Filomena Gallone, Angela Maria Vittoria Larocca, Cinzia Germinario, Silvio Tafuri. The author names have been corrected in the author list and the citation for this Erratum

    Justice, markets, and the family: an interview with Serena Olsaretti

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    Serena Olsaretti (Naples, Italy, 1971) is a political philosopher at Pompeu Fabra University (UPF), where she holds a research professorship with the Catalan Institute of Research and Advanced Studies (ICREA). Before moving to Barcelona, she was University Senior Lecturer at the Faculty of Philosophy of Cambridge University. She obtained a BA, MPhil, and DPhil degree in political philosophy from Oxford University. Her DPhil thesis was supervised by G.A. Cohen. Olsaretti’s research interests range widely, including the ethics of markets, justice and the family, feminist philosophy, theories of responsibility, and theories of well-being. She is the author of Liberty, desert and the market (2004), and the editor of Desert and justice (2003), Preferences and well-being (2006), and the Oxford handbook of distributive justice (forthcoming). Her work has appeared in various journals, including Analysis, Economics & Philosophy, Philosophy & Public Affairs, and Proceedings of the Aristotelian Society. Olsaretti is one of the editors of Law, Ethics, and Philosophy. She is the principal investigator of Family justice: an analysis of the normative significance of procreation and parenthood in a just society, a research project funded by a European Research Council (ERC) consolidator grant. The Erasmus Journal for Philosophy and Economics (EJPE) interviewed Olsaretti about becoming a political philosopher, her work on the ethics of markets and justice and the family, the ERC-project that she directs, her views on teaching, and her advice for political philosophy graduates aspiring to an academic career.This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation programme (Grant Agreement Number: 648610)

    Giurisprudenza romana nei papiri. Tracce per una ricerca

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    The volume presents a collection of essays devoted to circulation and transmission of Roman legal knowledge in Late Antiquity, focusing on the description, edition and commentary of legal fragments, on papyrus and parchment, from III to V c. AD; this period, between the classical age of Roman legal jurisprudence and the great enterprise of the Digest of Justinian, is usually considered of decadence in the traditional legal scholarship. The papyrus and parchment fragments, mostly found in archaeological excavation in the Eastern Part of the Roman Empire or kept in Western Libraries for centuries, contain texts different in topics and lengths: some are copies of works of classical legal literature (e.g., Ulpian), some others are Greek or Latin-Greek legal commentaries; a few of them bear text which are not known from other sources, therefore is not possible to guess if they are original works or commentaries in somebody else work; there are excerpts from different authors and works, interlinear and marginal glosses of considerable length. The same variety can be seen in their book formats (from fine parchments books to re-used papyrus leaves, from pocket books to wide margin pages, suitable to host long annotations) and scripts (from Latin legal uncial to cursive scripts; a considerable bilingual and digraphical evidence is here discussed, too). All this diversity is a significant witness of the lively word of Roman legal scholarship in Late Antiquity. Scholars from different Italian and foreign universities (Bari, Naples, Parma, Pavia, Rome, Siena, Zurich) present in this book the results of their investigations in the frame of the PRIN 2009 project ‘Legal literature in Late Antiquity (III-V c. AD). History and Geography’. Ulrico Agnati (Parma) e Serena Ammirati (Roma Tre-Pavia) present a re-edition and commentary of P.Oxy. XVII 2089, whose text is about marital legacies. Author and title of the work are unknown. Sergio Alessandrì offer a new exegesis of PSI XIV 1449, from book 32 of Ulpian, Ad edictum; Andrea Lovato discusses the contents of P.Fay. 10 and P.Berol. inv. 11533, a papyrus fragment about imperial dispositions on the legacy of the soldiers; and of Cod. Vind. 1b, which bears Ulpian Institutions; the essay of Federico Battaglia (Zurich) focuses on the structure and the definitions of PSI XIII 1348; to Valerio Marotta (Pavia) we owe a new commentary on P.Berol. inv. 6757, known as Fragmentum de iudiciis; Stefania Pietrini (Siena)’s paper is about the meaning of the marginal glosses preserved through P.Ant. III 152, on dowry and the related legal actions; Jolanda Ruggiero (Roma, Sapienza) presents the wellknown Fragments with the Sententiae of Paul, Leiden, BPL 2589. Fragments different in content are nonetheless very important to reconstruct the legal thinking of Late Antiquity: Maria Chiara Scappaticcio (Naples) edits and comments the legal glosses in P.Ryl. III 477, a papyrus collection of Cicero’s speeches; Serena Ammirati offers a survey of bilingual Greek-Latin glossaries and their graphic and textual interaction with legal fragments; Dario Mantovani (Pavia)’s reflections about the origin of Digest offer a new insight on the continuity in the transmission of Roman classical legal scholarship, which helps to frame all the fragments discussed in the book

    Justice, markets, and the family: an interview with Serena Olsaretti

    No full text
    Serena Olsaretti (Naples, Italy, 1971) is a political philosopher at Pompeu Fabra University (UPF), where she holds a research professorship with the Catalan Institute of Research and Advanced Studies (ICREA). Before moving to Barcelona, she was University Senior Lecturer at the Faculty of Philosophy of Cambridge University. She obtained a BA, MPhil, and DPhil degree in political philosophy from Oxford University. Her DPhil thesis was supervised by G.A. Cohen. Olsaretti’s research interests range widely, including the ethics of markets, justice and the family, feminist philosophy, theories of responsibility, and theories of well-being. She is the author of Liberty, desert and the market (2004), and the editor of Desert and justice (2003), Preferences and well-being (2006), and the Oxford handbook of distributive justice (forthcoming). Her work has appeared in various journals, including Analysis, Economics & Philosophy, Philosophy & Public Affairs, and Proceedings of the Aristotelian Society. Olsaretti is one of the editors of Law, Ethics, and Philosophy. She is the principal investigator of Family justice: an analysis of the normative significance of procreation and parenthood in a just society, a research project funded by a European Research Council (ERC) consolidator grant. The Erasmus Journal for Philosophy and Economics (EJPE) interviewed Olsaretti about becoming a political philosopher, her work on the ethics of markets and justice and the family, the ERC-project that she directs, her views on teaching, and her advice for political philosophy graduates aspiring to an academic career

    Introducion

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    The paper is Introduction to: Music of the twenty-first century disporas: research and problems, edited by the author and Giovanni Giuriati. It contains a contribution to some nodal questions about music and migration studies, applied to the Italian situation. In particular: 1. Who are we talking about; 2. Ethnomusicology and migration studies; Music: from migrants to the new “us”. The themes touched by the articles of the book are particularly considered and presented
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