19 research outputs found
Correction: Neural correlates of automatic emotion regulation and their association with suicidal ideation in adolescents during the first 90-days of residential care
No full textCorrection to: Translational Psychiatry 10.1038/s41398-023-02723-9, published online 23 January 2024
In this article, the affiliation details for Author Sahil Bajaj were incorrectly given as “Department of Cancer Systems Imaging, MD Anderson Center, South Campus Research Bldg, Houston, TX, USA”
but should have been “Department of Cancer Systems Imaging, MD Anderson Cancer Center, Houston, TX, USA”
The original article has been corrected
Publication rates from the All India Ophthalmic Conference 2010 compared to 2000: Are we improving?
No full textPurpose: To determine the publication rates of free papers and posters presented at the All India Ophthalmic Conference (AIOC) 2010 in peer-reviewed journals up to December 2015 and compare this with publication rates from AIOC2000 published previously. Methods: A thorough literature search was conducted using PubMed, Google Scholar, and the general Google search engine by two independent investigators. The title of the paper, keywords and author names were used to “match” the AIOC free-paper with the published paper. In addition, the “purpose,” “methods,” and “outcome measures” between the two were studied to determine the “match.” Results: A total of 58 out of 394 free-papers (14.7%) from AIOC2010 were published till December 2015 compared to 16.5% from AIOC2000. Out of these, 52 (90%) were published in PubMed indexed journals. Maximum publications were seen in pediatric ophthalmology (50%) followed by glaucoma (24.4%) and cornea (23.8%). Fifteen out of 272 posters (5.5%) were published; orbit/oculoplastics had the highest poster publications (13%). Excluding papers in nonindexed journals and those by authors with international affiliations, the publication rate was approximately 12%. Conclusion: The publication rate of free papers from AIOC2010 has marginally reduced compared to AIOC2000. Various causes for this such as lack of adequate training, motivation, and lack of incentives for research in the Indian scenario have been explored, and measures to improve this paradigm have been discussed. It will be prudent to repeat this exercise every decade to compare publication rates between periodic AIOC, stimulate young minds for quality research and educate policy makers toward the need for developing dedicated research departments across the country
Final Results from a Phase 2 Randomized, Placebo-Controlled Clinical Trial of RBX2660: A Microbiota-Based Drug for the Prevention of Recurrent Clostridioides difficile Infection
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Reimagined Chat Application
No full textReimagined Chat Application
Social media web application copy alongside the lines of Signal, Facebook, and Twitter. This will include functionality of posting, commenting, and sharing other user’s posts, user authentication, notifications, and private messaging. Using React we will able to develop our website, as well as using Node.js to handle package management. Users will be able to custom tailor a “post” to be accessible from other devices. A post will be described as a text or image upload. The author of the post as well as other users of the web application will be able to “comment” on existing posts. Comment defined as text or image response. Users will be able to “share” an existing post. Share is defined as posting a link or iframe instance of the other post
Clinical and functional outcomes of proximal femoral nailing in proximal femur fractures: a prospective study of 100 cases
Get PDFBackground: Intertrochanteric fractures are common in elderly osteoporotic patients and carry high morbidity and mortality if not treated adequately. Proximal femoral nailing (PFN) has been developed to overcome limitations of extramedullary fixation devices. Objectives were to evaluate functional and radiological outcomes of PFN in proximal femur fractures.
Methods: A prospective study of 100 patients with intertrochanteric femur fractures was conducted between March 2022 and July 2024. Patients were treated with PFN and followed up for 6-18 months. Functional outcome was assessed using the Harris hip score (HHS).
Results: The mean patient age was 648. years (28-95 years). Left-sided fractures (57%) were more common than right (43%). 68% fractures were unstable (Evan’s classification). Average interval from injury to surgery was 42 days, mean operative time 85 minutes. At one-year follow-up, 66% had excellent, 19% good, 10% fair, and 5% poor outcomes (mean HHS: 8882.). Complications occurred in 15% cases. No non-union was observed.
Conclusions: PFN is a reliable fixation method for intertrochanteric fractures, offering stable fixation, early mobilization, and favorable functional outcomes with minimal complications
Association Between Aggression and Differential Functional Activity of Neural Regions Implicated in Retaliation
No full textObjective: The goal of the current study was to determine the extent to which atypical neural responsiveness during retaliation is associated with observed aggression in youth in residential care. Method: This functional magnetic resonance imaging study involved 83 adolescents (56 male and 27 female; mean age, 16.18 years) in residential care performing a retaliation task. Of the 83 adolescents, 42 displayed aggressive behavior within the first 3 months of residential care, whereas 41 did not. During the retaliation task, participants were offered either fair or unfair divisions of 1, 3, punish the partner (retaliation phase). Results: The study's main findings were that aggressive adolescent showed the following: reduced down-regulation of activity within regions involved in representing the expected value of choice options (left ventromedial prefrontal cortex and left posterior cingulate cortex) as a function of offer unfairness and retaliation level; and reduced recruitment of regions implicated in response control (right inferior frontal gyrus and bilateral anterior insular cortex) and associated fronto-parietal regions as a function of retaliation level. The aggressive adolescents were also significantly more likely to have been aggressive prior to residential care and showed a strong trend for increased retaliation on the task. Conclusion: We suggest that individuals with a greater propensity for aggression show reduced representation of the negative consequences of retaliation and associated reduced recruitment of regions potentially involved in over-ruling these negative consequences to engage in retaliation. Diversity & Inclusion Statement: We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. We worked to ensure sex balance in the selection of non-human subjects. We actively worked to promote sex and gender balance in our author group. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work. While citing references scientifically relevant for this work, we also actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our reference list. While citing references scientifically relevant for this work, we also actively worked to promote sex and gender balance in our reference list. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group.</p
Efficacy and Health-Related Quality of Life Impact of Fecal Microbiota, Live-jslm: A Post Hoc Analysis of PUNCH CD3 Patients at First Recurrence of Clostridioides difficile Infection
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Formation of Mn-rich interfacial phases in Co2FexMn1-xSi thin films
No full textWe report the formation of Mn-rich regions at the interface of Co2FexMn1-xSi
thin films grown on GaAs substrates by molecular beam epitaxy (MBE). Scanning
transmission electron microscopy (STEM) with electron energy loss (EEL)
spectrum imaging reveals that each interfacial region: (1) is 1-2 nm wide, (2)
occurs irrespective of the Fe/Mn composition ratio and in both Co-rich and
Co-poor films, and (3) displaces both Co and Fe indiscriminately. We also
observe a Mn-depleted region in each film directly above each Mn-rich
interfacial layer, roughly 3 nm in width in the x = 0 and x = 0.3 films, and 1
nm in the x = 0.7 (less Mn) film. We posit that growth energetics favor Mn
diffusion to the interface even when there is no significant Ga interdiffusion
into the epitaxial film. Element-specific X-ray magnetic circular dichroism
(XMCD) measurements show larger Co, Fe, and Mn orbital to spin magnetic moment
ratios compared to bulk values across the Co2FexMn1-xSi compositional range.
The values lie between reported values for pure bulk and nanostructured Co, Fe,
and Mn materials, corroborating the non-uniform, layered nature of the material
on the nanoscale. Finally, SQUID magnetometry demonstrates that the films
deviate from the Slater-Pauling rule for uniform films of both the expected and
the measured composition. The results inform a need for care and increased
scrutiny when forming Mn-based magnetic thin films on III-V semiconductors like
GaAs, particularly when films are on the order of 5 nm or when interface
composition is critical to spin transport or other device applications.We acknowledge support from the National Science Foundation (NSF), USA through NSF-CAREER Award No. DMR-2047251. ICTS-CNME at UCM is acknowledged for offering access to STEM microscopy and expertise. ICMAB author acknowledges Spain’s Agencia Estatal de Investigación Severo Ochoa Program for Centers of Excellence in R&D (CEX2019-000917-S). The work at Washington University was supported by the NSF through awards # DMR-1806147 and DMR-2145797. A portion of the STEM experiments were performed at the Center for Nanophase Materials Sciences (CNMS), which is a US Department of Energy, Office of Science User Facility at Oak Ridge National Laboratory.With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2019-000917-S).Peer reviewe
Japanese language teaching in Malaysia and New Zealand: Recent history, current practice and curriculum
No full textComparisons of curriculum have been shown to be useful in terms of finding new ideas to raise the standard of education in one country and to enhance global competitiveness (Adamson & Morris, 2007). The purpose of the research reported in this thesis was to examine Japanese language education in Malaysia and New Zealand. The study compared the approach to Japanese language learning and teaching in both countries and also compared the curriculum and syllabus for both countries. This study employed three methods: semi-structured interview, autoethnography, and document analysis. Semi-structured interviews were conducted to find out the recent history and current practice of Japanese Language teaching in Malaysia and New Zealand. Four participants, one from Malaysia and three from New Zealand were involved in the interviews. Autoethnography was also infused in the research which permitted the author to share her knowledge and experiences as an experienced Japanese language teacher in Malaysia. The analysis of the curriculum and syllabus documents were carried out to look at the content of both countries‟ Japanese Language Curriculum to investigate its underpinning approach to language teaching, and to analyze the similarities and differences between the Malaysian and New Zealand Japanese Language Curricula.
The results show that both Japanese language curricula shared many similarities in terms of their types of syllabus, language learning aims and language areas focused in the curricula content. This indicates that Malaysia and New Zealand, like other countries in the world, follow international trends in language teaching.
Both countries‟ Japanese language syllabi have strong characteristics of Skills-Based and Outcomes-Based Syllabi. The curricula emphasize the acquisition of four very important language skills: listening, writing, reading and speaking. Both curricula promote teachers autonomy in decision-making and designing or planning programs. However, in comparison, New Zealand shows more teacher-autonomy than Malaysia. The findings also indicate that, although Japanese Language Curriculum in both Malaysia and New Zealand follows the global trends in language teaching, each also reflects its nation‟s visions and the needs of its people: Malaysian Japanese Language Curriculum was established to enable students to recognize and embrace the values that had brought Japan to its economic level now. While, Japanese language education in New Zealand starts because of the government‟s desire to trade and do business with Japan, a new economic power at the time
Risks to the clinician of risk management: Recalled and anticipated consequences of decision-making
Get PDF© 2025 Challinor, Bhandari, Boyle, Gabbay, Wilson, Saini and Nathan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.BACKGROUND: Despite extensive literature studying how we make decisions in the face of uncertainty, the empirical study of real-world clinical decision-making in mental health practice remains limited. Decisions in clinical settings are not just made on the basis of clinical factors. A key non-clinical influence on decision making is the clinician’s concerns about the ‘threat’ to themselves from a future adverse incident and the subsequent retrospective scrutiny of their decision-making. A better understanding of non-clinical processes is essential to inform better ways of guiding effective decision-making. More specifically, delineating the nature of this ‘threat’ process will also inform approaches to patient safety. AIMS: The objective of the current study was to delineate consequences recalled and anticipated by mental health clinicians making decisions under uncertainty. METHODS: This was an analysis of data arising from six focus group discussions with professionals involved in decisions to admit patients to psychiatric hospitals (consultant psychiatrists, approved mental health practitioners, crisis resolution home treatment teams, and liaison psychiatry practitioners) in one National Health Service Trust, UK. The data were thematically analyzed to identify the nature of ‘threat’ processes that arise in clinical decision-making. RESULTS: Themes identified included (i) the location of the effect of the anticipated/recalled consequence(s), (ii) the location of the origin of the consequence, and (iii) the nature of the consequence. The recalled and anticipated consequences of decision-making were overwhelmingly, but not exclusively, negative. The consequences were largely perceived to be directed towards the self (i.e., the clinician) and were considered to originate from external scrutiny by peers, organizational leadership, and the patient safety system/processes. CONCLUSIONS: The process of making decisions to admit patients to hospital consistently involved the decision-maker’s concern with the future consequences for them, either from a prior or future adverse event. The findings of this study, alongside other evidence of the complexity of decision-making, have implications for improving and studying clinical decision-making (and, by extension, patient care and outcomes), patient safety responses, and professional well-being.This article was supported by The National Institute for Health and Care Research Applied Research Collaboration North West Coast (NIHR ARC NWC
