224 research outputs found
Intravenous Dexamethasone Pulse Therapy For Extensive Alopecia Areata
No full textPatient with extensive alopecia areata (>30% scalp involvement) were given 32mg of dexamethasone in 200 ml of 5% dextrose intravenously on three consecutive days (total 96mg) every four weeks. Response was quantified as 1 to 25%, 25% to 50%, 50 to 75% and 75 to 100% of terminal hair growth by mapping and serial photographs. They were examined monthly for side effects of steroids. Six patients (5 male and 1 female) with a mean age of 32 years were recruited. They had alopecia areata for a period ranging from 3 months to 2.5 years. All the six cases did not show further worsening of alopecia after 3 pulses. However, two of them showed less than 25% hair growth after 4 pulses and did not turn up for follow up. In 2 cases, 25 to 50% growth was observed an 50 to 75% growth was seen in 2 patients (one of them with ophiasic pattern) after 6 pulses. The results were cosmetically acceptable for three of them. No adverse effect to steroids was encountered and the patients are still under follow up. The preliminary results show that dexamethasone pulse therapy is safe and effective for extensive alopecia areata
Successful Treatment Of Basal Cell Carcinoma Encroaching The Eyelid With CryofreeZe And Plastic Repair
No full text
Pruritus Gravidarum
No full textPruritus is a common symptom during pregnancy in 3-14% of all pregnancies. Pregnant women are as susceptible as non-pregnant women to ordinary pruritic skin disorders, but there are certain disorders, peculiar to pregnancy called as specific dermatoses of pregnancy. All these specific dermatoses of pregnancy are associated with primary skin lesions except pruritus gravidarum, which was only secondary skin lesions like excoriation marks. The incidence of pruritus gravidarum varies from 0.02 to2.4%. Several reports have shown a significantly increased incidence of prematurity, antepartum foetal distress and postpartum haemorrhage among these cases. Hence, a careful monitoring of pregnancy is advised in all such cases. Hence, a careful monitoring of pregnancy is advised in all such cases
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