831 research outputs found

    C. C. Mehta

    No full text
    On the life and works of Chandravadan Chimanlal Mehta, b. 1901, Gujarati author

    Circulating stem cells and cardiovascular outcomes: from basic science to the clinic

    No full text
    The cardiovascular and haematopoietic systems have fundamental inter-relationships during development, as well as in health and disease of the adult organism. Although haematopoietic stem cells (HSCs) emerge from a specialized haemogenic endothelium in the embryo, persistence of haemangioblasts in adulthood is debated. Rather, the vast majority of circulating stem cells (CSCs) is composed of bone marrow-derived HSCs and the downstream haematopoietic stem/progenitors (HSPCs). A fraction of these cells, known as endothelial progenitor cells (EPCs), has endothelial specification and vascular tropism. In general, the levels of HSCs, HSPCs, and EPCs are considered indicative of the endogenous regenerative capacity of the organism as a whole and, particularly, of the cardiovascular system. In the last two decades, the research on CSCs has focused on their physiologic role in tissue/organ homoeostasis, their potential application in cell therapies, and their use as clinical biomarkers. In this review, we provide background information on the biology of CSCs and discuss in detail the clinical implications of changing CSC levels in patients with cardiovascular risk factors or established cardiovascular disease. Of particular interest is the mounting evidence available in the literature on the close relationships between reduced levels of CSCs and adverse cardiovascular outcomes in different cohorts of patients. We also discuss potential mechanisms that explain this association. Beyond CSCs' ability to participate in cardiovascular repair, levels of CSCs need to be interpreted in the context of the broader connections between haematopoiesis and cardiovascular function, including the role of clonal haematopoiesis and inflammatory myelopoiesis

    Mobilities in Religious Knowledge: Phiroz Mehta and the Logics of Transreligiosity in 1970s–80s South London

    No full text
    This paper examines transreligiosity in the context of the transmission of South Asian concepts of spirituality to the UK in the 20th century. Between the 1920s and 1990s, Indian teacher and author Phiroz Mehta (1902–1994) crossed borders in a colonial and postcolonial shuttling between India and the UK but also transgressed conceptual and practice borders of religion, teaching Indian religious concepts to post-Christian spiritual seekers in 1970s–80s South London. Mehta cultivated an elasticity between many religious and philosophical traditions, recognising the post-institutional fatigue of subjects who sought alternative forms of ‘belonging without believing’. Privileging the domestic space for teaching, as well as transitory ‘camp’ gatherings in the UK and Germany, Mehta often operated in the social margins, combining teachings from Hinduism, Buddhism, and Christianity with Zoroastrianism, Judaism (specifically Kabbalah), and Daoism. He offered his tutees the freedom to practice religion in whatever way they chose by drawing on a broad range of traditions concurrently to create a transreligiosity. This paper examines Panagiotopoulos and Roussou’s ‘transgressional webs of practising individualised forms of alternative spirituality’ in relation to Mehta’s followers in the 1970s-1980s and asks how transreligiosity relates to other theoretical analyses, such as religious exoticism, bricolage, religious appropriation, cultural re-articulation or assemblage. This paper focuses on qualitative interviews with original members of the Mehta community conducted between 2021 and 2022.</p

    Design and development of a mechatronic training simulator for adult ECMO

    No full text
    Widespread adoption of Extracorporeal Membrane Oxygenation (ECMO) in adults has been limited by unfamiliarity with the procedure, including cannulation and safe handling of the ECMO equipment. We present the design and development of a mechatronic training simulator for ECMO that can help medical professionals acquire the needed skills, gain familiarity, and reduce errors by practicing before performing the procedure on real patients. The trainer is designed as an ultrasound-compatible, wholesome simulator with realistic components such as synthetic blood vessels, cannulation pads, and a color-changing blood simulant to simulate oxygenation and deoxygenation. The simulator is integrated with a mathematical model of human physiology to simulate real-time patient vitals and training scenarios, and to control the trainer hardware. We present results related to successful cannulation under ultrasound scanning and a simple patient scenario of hypovolemia.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-05-01The student, Iti Mehta, accepted the attached license on 2019-04-24 at 10:58.The student, Iti Mehta, submitted this Thesis for approval on 2019-04-24 at 11:11.This Thesis was approved for publication on 2019-04-24 at 12:45.DSpace SAF Submission Ingestion Package generated from Vireo submission #13873 on 2019-08-22 at 15:08:02Made available in DSpace on 2019-08-23T20:36:09Z (GMT). No. of bitstreams: 2 MEHTA-THESIS-2019.pdf: 84393765 bytes, checksum: 74f0edf247057995595372eb8076e513 (MD5) LICENSE.txt: 4206 bytes, checksum: 30fb64a86cfc352d6579ccb023b2a936 (MD5) Previous issue date: 2019-04-24Embargo set by: Seth Robbins for item 112203 Lift date: 2021-08-23T20:36:18Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 112203 on 2021-08-24T09:15:24Z

    Optimal Bioeconomic Management Strategies for Prevention and Control of Invasive Alien Species

    No full text
    Paper removed by author. Please see the current version, available online January 8, 2007: Mehta, S.V. et al. Optimal detection and control strategies for invasive species management. Ecological Economics (2007), doi:10.1016/j.ecolecon.2006.10.024Environmental Economics and Policy,

    Design and implementation of a phase locked loop for high-speed serial links

    No full text
    The student, Rushabh Mehta, accepted the attached license on 2016-04-25 at 13:40.The student, Rushabh Mehta, submitted this Thesis for approval on 2016-04-25 at 13:46.This Thesis was approved for publication on 2016-04-27 at 14:52.DSpace SAF Submission Ingestion Package generated from Vireo submission #9475 on 2016-07-07 at 13:50:45Made available in DSpace on 2016-07-07T20:27:59Z (GMT). No. of bitstreams: 2 MEHTA-THESIS-2016.pdf: 13984347 bytes, checksum: 4ecb06c5c270bc1beffb061eeae85eef (MD5) LICENSE.txt: 4210 bytes, checksum: e6aea67d4e02d64f06671bb40ada2274 (MD5) Previous issue date: 2016-04-27Recent advances in the semiconductor industry and process technology scaling have increased the demand for fast, robust computing. The thirst for high-processing, low power ICs is ever increasing. This has pushed the demand for high data rates in wireless and wireline communication systems in the multi-Gbps range. With higher data rates, the I/O links need to scale proportionally. However, the I/O channel bandwidth has not scaled appropriately making it the biggest bottleneck in high-speed links. Parallel links have not been able to match this increasing system performance due to issues such as crosstalk, timing skew and packaging costs. Thus there is a need for high-speed serial links. For high-speed transmission of data, there arises a need for high-speed on chip clocking circuits making the use of Phase-Locked Loops (PLLs) imperative. This thesis includes an overview of high-speed links along with the need for PLLs. An in-depth understanding of PLL theory, loop dynamics and behavioral and transistor level simulation follows. Performance metrics such as phase noise, random jitter and deterministic jitter are discussed. Finally, this thesis concludes with an insight into All Digital Phase-Locked Loops (ADPLLs).Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2018-05-01Embargo set by: Seth Robbins for item 93174 Lift date: 2018-07-07T20:28:14Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 93174 Lift date: 2018-07-07T20:35:34Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 93174 on 2018-07-08T09:15:20Z

    Visual outcomes of bilateral congenital and developmental cataracts in young children in south India and causes of poor outcome.

    No full text
    CONTEXT: Bilateral pediatric cataracts are important cause of visual impairment in children. AIM: To study the outcome of bilateral pediatric cataract surgery in young children. SETTING AND DESIGN: Retrospective case series in a tertiary center. MATERIALS AND METHODS: Records of pediatric cataracts operated between January 2001 and December 2003, with a minimum follow-up of 3 months, were reviewed retrospectively. STATISTICAL METHODS: Independent sample t-test, Fisher's exact test, and logistic regression using SPSS (Statistical Package for Social Science, Chicago, USA) version 12. RESULTS: 215/257 (83.7%) patients had a minimum follow-up of 3 months. The mean age of presentation to the hospital was 53 months (range: 0-168 months). Congenital cataract was present in 107 patients (58.2%) and developmental cataract in 77 patients (41.8%). The mean age at surgery was 55.2 months (range: 1-168 months). Out of 430 eyes, 269 (62.6%) had an intraocular lens implanted. The mean duration of follow-up was 13.1 months (range: 3-38 months). Pre-operatively, 102 patients (47.3%) had visual acuity 6/18. The most common early post-operative complication was fibrinous uveitis in 57 eyes (13.3%) and the most common delayed post-operative complication was posterior capsular opacification in 118 eyes (27.4%). The most important prognostic factor for poor outcome was congenital cataract (odds ratio [OR]: 26.3; 95% confidence interval [CI], 4.4-158.5) and total cataract (OR: 4.8; 95% CI, 1.3-17). CONCLUSION: Nearly half of the eyes had visual acuity >6/18. The outcome was poorer in congenital cataracts, especially those operated after >1 year of age

    Analyzing Advancement in Crowdfunding Research and Envisioning its Future: A Bibliometric Approach

    No full text
    Published online 24 July 2023. Published in print 1 August 2023.Academy of Management Annual Meeting Proceedings includes abstracts of all papers and symposia presented at the annual conference, plus 6-page abridged versions of the “Best Papers” accepted for inclusion in the program (approximately 10%). Papers published in the Proceedings are abridged because presenting papers at their full length could preclude subsequent journal publication. Please contact the author(s) directly for the full papers.Crowdfunding represents an emerging alternative means of marshaling resources which may prove to be a game-changer in the entrepreneurial finance landscape. Although the rapid growth in this field has yielded a multidisciplinary body of work, the scaffolding of this vast body of work is still largely unknown in the scholarly domain. We conduct a bibliometric analysis of 534 crowdfunding articles to uncover the intellectual landscape of crowdfunding research. Our comprehensive co-citation analysis reveals two generations of crowdfunding research, identifies the most researched themes in area, and highlights its theoretical and disciplinary anchors. In addition, our bibliographic cartography traces the shifts in areas of interest of scholars within the heterogeneous field. Overall, our critical analysis of the most influential conversations in crowdfunding research helps reveals gaps in the extant literature which act as fertile directions for its future inquiry

    Orthogonality Relations and Cherednik Identities for Multivariable Baker-Akhiezer Functions

    No full text
    Author Manuscript 27 Feb 2013We establish orthogonality relations for the Baker–Akhiezer (BA) eigenfunctions of the Macdonald difference operators. We also obtain a version of Cherednik–Macdonald–Mehta integral for these functions. As a corollary, we give a simple derivation of the norm identity and Cherednik–Macdonald–Mehta integral for Macdonald polynomials. In the appendix written by the first author, we prove a summation formula for BA functions. We also consider more general identities of Cherednik type, which we use to introduce and construct more general, twisted BA functions. This leads to a construction of new quantum integrable models of Macdonald–Ruijsenaars type.National Science Foundation (U.S.) (Grant DMS-1000113
    corecore